News

Dear Friends

Parkinson’s is a neurological disease characterized by mitochondrial dysfunction and oxidative stress in the dopaminergic neurons of the mid brain, causing them to die, resulting in motor dysfunction.

Parkinson’s (PD) has been positively associated with two groups of pesticides, those that impair mitochondrial function and those that increase oxidative stress.  Two such pesticides are paraquat, which causes oxidative stress, and rotenone, which inhibits mitochondrial complex I, both induce loss of nigral dopaminergic neurons and behavioral changes associated with human PD.

Epidemiological findings suggest that the consumption of berries rich in anthocyanins and proanthocyanidins may reduce PD risk.  Strathearn et al. (2014) demonstrated powerful protective effects of blueberry extract in protecting the neurons from the oxidative damage of the pesticides.  In their study, they investigated whether extracts rich in anthocyanins, proanthocyanidins, or other polyphenols, suppress the neurotoxic effects of rotenone in a primary cell culture model of PD.

Extracts rich in anthocyanins and proanthocyanidins exhibited greater neuroprotective activity than extracts rich in other polyphenols, and a number of individual anthocyanins interfered with rotenone neurotoxicity.  The blueberry and grape seed extracts rescued rotenone-induced defects in mitochondrial respiration in a dopaminergic cell line.

Dr. Mary Ann Lila, one of the study’s team of scientists, and the director of North Carolina State University’s Plants for Human Health Institute stated:

Blueberries have both of these natural chemicals (anthocyanins and proanthocyanidins) in high concentrations, so they pack a more powerful, one-two punch.  They can have synergistic benefits that surpass many other fruits when it comes to protection against brain cell death, which in turn may reduce the risk of contracting Parkinson’s.(Moore, 2014)

A cup a day is a good routine for health, according to Lila, and it provides abundant amounts of vitamins A and C, fiber, manganese and phytonutrients, which have antioxidant and anti-inflammatory properties.  Blueberries are also a “brain food”, and have been shown to increase powers of concentration and slow cognitive degeneration.

Our  Blueberry Extract (1 capsule) has a cup and a quarter of blueberries, while the Phyto Power (2 capsules) has 200mg of four species of wild harvested blueberries plus 400 mg of rosehips with their powerful collection of flavonoids including proanthocyanidins.

We will focus on these cognitive benefits in our next Forward Thinking.

References

Moore, J. (2014). Blueberries reduce risk of Parkinson’s, boost brain function finds new study. Plants for human health institute, NC State. Article

Strathearn, K. E., Yousef, G. G., Grace, M. H., Roy, S. L., Tambe, M. A., Ferruzzi, M. G., … & Rochet, J. C. (2014). Neuroprotective effects of anthocyanin-and proanthocyanidin-rich extracts in cellular models of Parkinson׳ s disease. Brain research, 1555, 60-77. Article

Tanner, C. M., Kamel, F., Ross, G. W., Hoppin, J. A., Goldman, S. M., Korell, M., … & Comyns, K. (2011). Rotenone, paraquat, and Parkinson’s disease. Environmental health perspectives, 119(6), 866-872. Article

Best,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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It is estimated that one million people suffer from Parkinson’s in the U.S., and although the disease itself is not fatal, complications arising from it can be, and the CDC states that these co-morbidities result in it being the 14th leading cause of death in the country (National Parkinson Foundation).

 

©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

Last week one of our doctors reported the following successful protocol for a new patient with a declining condition of Parkinson’s Disease (PD).  The patient could barely walk.

After analysis, the doctor added these three products:

After two months the patient is now walking 4 miles a day.  And was having increasingly long stretches where she was feeling very well.

Gao et al., (2012) found that daily intake of dietary flavonoids lowers the risk of developing Parkinson disease in a large cohort of 49,281 men and 80,336 women that were followed for 20-22 years.  In general, high amounts of flavonoids, such as anthocyanins, quercetin, epicatechin, and proanthocyanidins were found to be protective. People who eat less blueberries and strawberries are more likely to develop PD. During that time 438 men and 367 women developed Parkinson Disease. Other studies show that blueberry and strawberry extracts increase dopamine release alleviating oxidative stress and suppressing neuroinflammation (Balk et al., 2006).

A number of factors play into the risk reduction or even a turnaround into better health: researchers have known for a long time that more fiber and lower animal fats reduce the risk of PD (Renoudet et al, 2012). The combination of fiber, probiotics (to produce L-dopa), and polyphenols in the Beta Glucan and No 7 all play part in the healthy functioning of our nervous system.

Our protocols add the Phyto Power and Blueberry Extract for a powerful addition of polyphenols. We’ll discuss these two products in our next email.

References

Balk, E., Chung, M., Raman, G., Tatsioni, A., Chew, P., Ip, S., … & Lau, J. (2006). B vitamins and berries and age-related neurodegenerative disorders. Evid Rep Technol Assess (Full Rep), 134, 1-161.

Gao, X., Cassidy, A., Schwarzschild, M. A., Rimm, E. B., & Ascherio, A. (2012). Habitual intake of dietary flavonoids and risk of Parkinson disease. Neurology, 78(15), 1138-1145.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320056/

Renoudet, V. V., Costa-Mallen, P., & Hopkins, E. (2012). A diet low in animal fat and rich in N-hexacosanol and fisetin is effective in reducing symptoms of Parkinson’s disease. Journal of medicinal food, 15(8), 758-761.

Best,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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The ultimate serious drink, the No 7 Longevity is bursting with a vital assortment of green leafy and hardy vegetables, fruits and berries concentrates, the BioImmersion Super Blend of naturally occurring whole probiotics with their supernatant and ORNS, fiber, and purposely selected nutriceuticals. The No 7 is defiantly powerful.*

 

©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

The scientific field of Longevity studies the forces that create chronic disease globally and the method that can reverse and prevent these illnesses.  We created potent formulas based on their studies and findings.

Immunosenescence and inflammageing are two key causative forces that are linked with the diseases of our time—metabolic syndrome, obesity, diabetes, heart disease, cancer, neurological disease, and other NCDs (Calder et al., 2017).

Franceschi (2014) has coined the term, Inflammageing:  As we age the concentration of pro inflammatory molecules increase in our blood stream—including acute phase proteins (CRP and serum amyloid A), cytokines (TNF-α, IL-1β, IL-6, IL-8), and adhesion molecules (sICAM-1 and sVCAM-1) amongst others.  The key to reversing chronic diseases and attaining a healthy life and longevity is to have plenty of anti-inflammatory molecules aboard and this can be attained through a specific diet and supplementation.

Immunosenescence:  One common characteristic of ageing is a decline in innate and acquired immune function, called immunosenescence, which increases ones susceptibility to infection.  The preserving of a healthy and strong immune system can be prolonged through a healthy anti-inflammatory food supplementation that turns on our endogenous antioxidant producing genes and networks; as well as to providing the kinds of fiberous and polyphenol rich foods that promote the development of a healthy, life- supporting gut microbiome.

BioImmersion’s Therapeutic Food Supplements are designed to mitigate micro-macro inflammation, the chronic low-grade inflammation (LGI) that is linked to our toughest chronic illnesses. Each formula is built with potent ingredients, concentrated foods that are highly researched as well as probiotics with their supernatant and ORNs (Holscher, 2017).

Call or email us to continue this conversation.

References:

Calder, P. C., Bosco, N., Bourdet-Sicard, R., Capuron, L., Delzenne, N., Doré, J., … & Visioli, F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing research reviews40, 95-119. Article

Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences69(Suppl_1), S4-S9. Article

Holscher, H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes8(2), 172-184. https://doi.org/10.1080/19490976.2017.1290756

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

 

Green Facts:

Globe_Home 3

The ultimate serious drink, the No 7 Longevity is bursting with a vital assortment of green leafy and hardy vegetables, fruits and berries concentrates, the BioImmersion Super Blend of naturally occurring whole probiotics with their supernatant and ORNS, fiber, and purposely selected nutriceuticals. The No 7 is defiantly powerful.*

 

©2005 – 2019 BioImmersion Inc. All Rights Reserved

What is the New Longevity

February 15, 2019
Dear Friends

What is the New Longevity?

We have powerfully upgraded some of our key products according to the research on the new longevity.

On Feb. 22nd, Friday morning, I will teaching with Drs. Artemis Morris and Dohrea Bardell the science behind the New Longevity at the IHS Convention in Manhattan.  Come join us for a breakfast and a great conversation. Learn about this newer branch of research on how to prevent and even reverse chronic illnesses.

The Integrative Healthcare Synposium (IHS) is in its 15th year, and is the only event where multi-disciplinary practitioners come together as a cohesive community.  Attendees gather each year to connect, learn, celebrate, and return to their practices with insights and techniques they can immediatly incorporate into their practices.  It’s from Feb. 21-23.

We will serve breakfast for the doctors on Friday morning at 7:15 to 8:00 am.

 What_is_the_New_Longevity?

If you can’t make it there, I am happy to set up a zoom meeting with you, where you can enjoy the presentation from your office or home.  Just call us 425-451-3112 to set it up.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The ultimate serious drink, the No 7 Longevity is bursting with a vital assortment of green leafy and hardy vegetables, fruits and berries concentrates, the BioImmersion Super Blend of naturally occurring whole probiotics with their supernatant and ORNS, fiber, and purposely selected nutriceuticals. The No 7 is defiantly powerful.*

 

©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Doctor

The proprietary mix of plant minerals and apple extract in our new product ENERGY was used in a double blind research by Joy et al. (2016). The research demonstrated that the mix increases energy and enhances performance during exercise. The mix also helped relax sore muscles from over exercising. We suggest one capsule a day or when you need extra energy.

ENERGY

The Research

Twenty-five healthy, resistance-trained, male subjects completed this double-blind study.  All subjects were prohibited from using any supplements not provided in the study except for a multivitamin or protein powder food substitute, which they were not permitted to use within 2 hours before or after resistance training sessions.

Each subject was required to be capable of lifting 1.5 times their bodyweight in the squat and deadlift and 1 times bodyweight in the bench press.  At baseline, the placebo group (PLA) was able to squat 1.71, bench press 1.45, and dead lift 2.17 times their bodyweight; and the treatment (TRT) was able to squat 1.66, bench press 1.31, and deadlift 1.93 times their bodyweight.

Subjects were randomly assigned to either the PLA or TRT groups.  The TRT got 1 serving of 150mg of the proprietary blend of Energy, which is one capsule. And, the PLA group got the placebo.  The single capsule dose was given 45 minute prior to training on training days or at a similar time of day on rest days.

The resistance training program, weeks 1-8, consisted of one muscle hypertrophy-oriented workout, one power-oriented workout, and one strength-oriented workout featuring cycle ergometer Wingates following strength training.

The back squat, bench press, and deadlift exercises were performed on each day along with several other multi- and single-joint exercises.  Participants rested 48-72 hours between each training day.  During the overreach phase (weeks 9 and 10), participants performed high volume workouts on Monday through Thursday with a strength-oriented workout or performance testing conducted on Friday for weeks 9 and 10, respectively.

The taper phase (weeks 11 and 12) consisted of one power day on Mondays then strength and power days on both Wednesdays and Fridays performed at low volume for back squat, bench press, and deadlift only.

The Results

Energy appeared to beneficially augment strength and power adaptations to resistance training and attenuate power loss during overreaching (over exercising).  Squat and deadlift IRM both increased to a greater degree in TRT than in PLA,  Peak power in the vertical jump seemed to increase as a result of training and supplementation, and vertical jump peak power and peak velocity did not decline following overreaching.  Strength endurance was preserved during overreaching in TRT compared to PLA. The proprietary blend of ancient peat and apple extracts may be better suited to resist performance decrements, as a decline in performance was only observed in the PLA group in the present study

Reference

Joy, J. M., Vogel, R. M., Moon, J. R., Falcone, P. H., Mosman, M. M., Pietrzkowski, Z., … & Kim, M. P. (2016). Ancient peat and apple extracts supplementation may improve strength and power adaptations in resistance trained men. BMC complementary and alternative medicine, 16(1), 224. https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1222-x

Sincerely yours,

Seann

Green Facts:

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Dr. Dohrea Bardell’s new book, Living Well – Dying Well (2018, chapter 8), has plenty of advice on increasing energy and stamina. The foundation is a whole food, plant-based diet that keeps our bodies protected and energized.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved