News

The Chromium is here!

January 9, 2019

Dear Doctor

Our new Chromium has arrived!

The formula 9 times stronger, with 50mcg of elemental trivalent chromium per capsule (6mcg in the old chromium), and with high active beet root, standardized to 10,000ppm nitrate.

The new Chromium is also trivalent:  the ligand on each of the chromium ion ports is a molecule of nicotinic acid (in other words, niacin), in contrast to the nucleotide sugars from brewers’ yeast.

The supplemental facts on the label lists only the weight of the elemental chromium (50mcg), rather than the whole Chromium polynicotinate molecule, which is 500mcg.

The High Active Beet Root is also very powerful: it is standardized to offer a minimum of 10,000ppm plant nitrate. Our bodies convert plant nitrate into nitric oxide, an important nutrient that relaxes blood vessel muscles, opening up circulation. And of course, the high active beet root offers betalains, a unique polyphenolic molecule in beet root with very strong antioxidant, antimicrobial, and anti-inflammatory properties.

Chromium Label Jpeg

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

In this fascinating website you can watch the numbers of births and the number of deaths growth in real time.  See Current World Population.  With the increasing numbers of people reaching sennescense and the mounting pandemic of chronic degenerative diseases, we need a sea-change in how we feed ourselves, to one that brings healthy longevity.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Inflammation and Aging

January 2, 2019

Dear Friends,

Let’s continue our discussion on achieving longevity: What are the reason(s) behind the design of the No 7 New Longevity?

We defined longevity as a healthy state, free from  chronic illnesses.

The global numbers for chronic illnesses are alarming: chronic diseases are responsible for about 35 million deaths each year (United Nations, Ageing, 2017; Living Well, Dying Well, Chronic Illnesses, 2018, p. 119).

In the United States, 85% of people who are over 65 years of age suffer from one or two chronic illnesses, and nearly a quarter of children that are under 17 years old suffer one or more chronic conditions, with almost half of young to mature adults (18 to 64 years old) having one or more chronic illnesses (2018, Living Well, Dying Well, p. 120). That means that about a half of our population is constantly dealing with chronic conditions. On one hand, our life span has increased, but on the other hand, healthy longevity seems very far off the radar for people here and the world.

Did you realize that we actually have known that inflammation is a slowly debilitating killer since the late 1800s? Already in 1913, Dr. Arnold Lorand seminal work, Health and Longevity through Rational Diet, summarized the connection between inflammation and disease:

The majority of the diseases with which mankind is afflicted usually creep in through the accumulated effects of successive slight irritation, by the operation of apparently insignificant factors which are just sufficient to take part in some chemical reaction. (p. 115)

Calder et al. (2017) characterize aging as an increase in the concentration of inflammatory markers in the blood stream, a phenomenon that has been termed “inflammageing”(see Franceschi & Campisi, 2014; Franceschi et al., 2007; Franceschi et al., 2000).*

Key to longevity and anti-aging is the approach of calming inflammation, micro and macro inflammation, seen as the intrinsic biological aging clock (Luo et al., 2011). Along with inflammation, the ageing of the immune system, called immunosenescence, is an age-related decline of the immune system that leads to an increased frequency and severity of infectious diseases and certain cancers (Solana & Pawelec, 2004; Clements & Carding, 2016; Bauer & Fuente, 2014).

Immunosenescence is brought about by a continuous chronic antigenic (toxins inducing) immune response which then overloads the ability of the immune system to keep up with the demands for naïve cells, the component of cells that enable the body to fight off new, unrecognized infections or diseases (Candore et al., 2006; Calder et al., 2018).*

Once chronic inflammation is activated, it becomes a system-wide condition that leads to higher mortality rates from different illnesses (e.g., Bozzetto et al., 2018; AHA, 2017; Clements & Carding, 2016; Morrisette-Thomas et al., 2014). A study on 1018 Italian old persons demonstrated that higher levels of certain inflammation-related mediators such as IL- 6, IL-1ra ,TNA-a, TNF- a receptor II (TNFAR2) were associated with higher number of chronic illnesses, such as hypertension, diabetes, ischemic heart disease, stroke, cancer, Parkinson’s, hip fractures, joint diseases, anemia, kidney disease, and cognitive impairment (Fabbri et al., 2015).*

Longevity is a balanced state of pro- and anti-inflammatory mediators. By protecting the body against the harmful effects of inflammation with high levels of anti-inflammatory molecules, long-life with better health is attainable. For example, Le Couteur et al. (2016) explain the profound effects nutrition has on ageing and longevity, with animal studies showing longevity is achieved with a specific diet that is similar to the dietary traditions of the long-lived people on the island of Okinawa – a predominantly plant based diet.*

Many scientists have come to realize that health, longevity, and anti-aging are fundamentally dependent upon the correct nutritional strategy that facilitates and educates the body’s defense, repair, adaptation, and renewal functions (Calder et al., 2017; Mykytyn, 2005). *

In fact, scientific research insists upon the daily consumption of plant-based foods, probiotics and their fermented metabolites, plenty of fiber, and particular nutriceuticals to achieve and sustain longevity: the healthy systemic functions of the body (Seidelmann et al., 2018; Devi & Sekhar, 2018; Filosa et al, 2018; Donoiu et al., 2018; Iskar & Antonyak, 2018; Smith & Hsu, 2018; Holscher, 2017).*

The No7 Longevity is designed with what science considers the best nutritional molecules that support the body’s ability to to defend, repair, adapt and renew.

We will continue this conversation!

References

American Heart Association. (2017, March 09). Unhealthy diets linked to more than 400,000 cardiovascular deaths [AHA/ASA Newsroom]. Retrieved from Article

Bardell, D. (2018). Living with chronic illness: Better health through lifestyle medicine.  In Stevens-Long, J., Bardell, D., Living Well, Dying Well. Fielding University Press.

Bauer, M. E., & De la Fuente, M. (2014). Oxidative stress, inflammaging, and immunosenescence. In Inflammation, Advancing Age and Nutrition (pp. 39-47). https://doi.org/10.1016/B978-0-12-397803-5.00004-6

Bozzetto, L., Costabile, G., Della Pepa, G., Ciciola, P., Vetrani, C., Vitale, M., … & Annuzzi, G. (2018). Dietary fibre as a unifying remedy for the whole spectrum of obesity-associated cardiovascular risk. Nutrients10(7), 943. DOI:10.3390/nu10070943

Calder, P. C., Bosco, N., Bourdet-Sicard, R., Capuron, L., Delzenne, N., Doré, J., … & Visioli, F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing research reviews40, 95-119. Article

Candore, G., Colonna-Romano, G., Balistreri, C. R., Carlo, D. D., Grimaldi, M. P., Listì, F., … & Caruso, C. (2006). Biology of longevity: role of the innate immune system. Rejuvenation research9(1), 143-148. Abstract

Clements, S. J., & Carding, S. R. (2016). Can Nutritional Intervention Counteract Immunosenescence in the Elderly?. In Molecular Basis of Nutrition and Aging (pp. 375-391). https://doi.org/10.1016/B978-0-12-801816-3.00028-5

Donoiu, I., Militaru, C., Obleagă, O., Hunter, J. M., Neamţu, J., Biţă, A., … & Rogoveanu, O. C. (2018). Effects of Boron-Containing Compounds on Cardiovascular Disease Risk Factors–A Review. Journal of Trace Elements in Medicine and Biology. Abstract

Fabbri, E., An, Y., Zoli, M., Simonsick, E. M., Guralnik, J. M., Bandinelli, S., … & Ferrucci, L. (2014). Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences70(1), 63-70. https://doi.org/10.1093/gerona/glu127

Filosa, S., Di Meo, F., & Crispi, S. (2018). Polyphenols-gut microbiota interplay and brain neuromodulation. Neural regeneration research13(12), 2055. Article

Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences69(Suppl_1), S4-S9. Article

Franceschi, C., Capri, M., Monti, D., Giunta, S., Olivieri, F., Sevini, F., … & Cevenini, E. (2007). Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mechanisms of ageing and development128(1), 92-105. https://doi.org/10.1016/j.mad.2006.11.016

Franceschi, C., Bonafè, M., Valensin, S., Olivieri, F., De Luca, M., Ottaviani, E., & De Benedictis, G. (2000). Inflamm‐aging: an evolutionary perspective on immunosenescence. Annals of the New York Academy of Sciences908(1), 244-254. Abstract

Holscher, H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes8(2), 172-184. https://doi.org/10.1080/19490976.2017.1290756

Le Couteur, D. G., Solon-Biet, S., Wahl, D., Cogger, V. C., Willcox, B. J., Willcox, D. C., … & Simpson, S. J. (2016). New Horizons: Dietary protein, ageing and the Okinawan ratio. Age and ageing45(4), 443-447. Article

Lorand, A., (1013). Health and Longevity through a Rational Diet.

Luo, C., Urgard, E., Vooder, T., & Metspalu, A. (2011). The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging. Medical hypotheses77(2), 174-178. https://doi.org/10.1016/j.mehy.2011.04.002

Morrisette-Thomas, V., Cohen, A. A., Fülöp, T., Riesco, É., Legault, V., Li, Q., … & Ferrucci, L. (2014). Inflamm-aging does not simply reflect increases in pro-inflammatory markers. Mechanisms of ageing and development139, 49-57. https://doi.org/10.1016/j.mad.2014.06.005

Mykytyn, C. E. (2006). Anti-aging medicine: A patient/practitioner movement to redefine aging. Social Science & Medicine62(3), 643-653. https://doi.org/10.1016/j.socscimed.2005.06.021

Seidelmann, S. B., Claggett, B., Cheng, S., Henglin, M., Shah, A., Steffen, L. M., … & Solomon, S. D. (2018). Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. The Lancet Public Health3(9), e419-e428. Article

Solana R. & Pawelec, G. (2004). Immunosenescence. NeuroImmune Biology, 4, 9-21.

Untied Nations, Ageing (2017),  http://www.un.org/en/sections/issues-depth/ageing/ n

 

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

In this fascinating website you can watch the numbers of births and the number of deaths growth in real time.  See Current World Population.  With the increasing numbers of people reaching sennescense and the mounting pandemic of chronic degenerative diseases, we need a sea-change in how we feed ourselves, to one that brings healthy longevity.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

A Healthy Longevity

December 31, 2018

Dear Friends

What is longevity?  What brings on the glow of a robust health in both younger and older people? According to the US National Institute of Aging (NIA), longevity is about measured strategies to extend the healthy functioning of our body (Nadon et al., 2008) – these strategies aim to prevent diseases, especially chronic illnesses like cardiovascular and cancer, among others (Caprara, 2018).*

Globally, while the average life span has increased in both developed and developing nations, in the next 30 years the aging population will double to 22%, or about 2 billion people. Since there are about 7.7 billion people in the world, this means that almost a quarter of the world will be over 60 years old (United Nations, Ageing, 2017).*

Old age causes a variety of biological and cognitive degenerations, yet the decline does not have to be debilitating. Just the opposite, with the correct approach toward prevention, healthy longevity can be achieved (Jin et al., 2015). The World health Organization (WHO) has focused their efforts on addressing non-communicable diseases (NCDs), or chronic illnesses, such as cancer, ischemic heart diseases, stroke, type 2 diabetes, Alzheimer’s disease and more, as a preventative approach and a path toward longevity (WHO, 2014; see also Lim et al., 2012 global assessment of both infectious and NCDs diseases).

Historically, in the developed world, longevity was thought of as an anti-aging approach that emphasized looks and energy rather than the whole health. Skin care, makeup, supplements, hormones, and medicines were created to hide age and stimulate our bodies into producing more energy and higher hormonal levels. Merchandise was fused with procedures to tighten or erase wrinkles and skin discolorations, sucking or adding fat, depending on the area treated, to name a few treatments (e.g., Ganceviciene et al., 2012). Mostly, the anti-aging movement was aimed to make women look younger and men more virile.*

The New Longevity represents a comprehensive approach to health and long life (Jin et al., 2015). This new approach to longevity (or healthy ‘anti-aging’) does not solely focus on how we look but how our bodies function healthily from youth to old age (Fontana et al., 2014).

[To be continued in 2019!]

No. 7 Pyramid photo
What is in the mix?

Phytonutrients– Organic strawberry, raspberry, blueberry, tart cherry, elderberry, cranberry, apple extract, pineapple, beet, kale leaves, spinach leaves, broccoli florets.

BioImmersions Probiotic Super Blend:  The proprietary blend includes: Probiotics-Bifidobacterium longum, Lactobacillus casei, Lactobacillus acidophilus, Lactobacillus bulgaricus, Streptococcus thermophilus; Prebiotics-Inulin from Chicory root; Supernatant-nutritional metabolites from each of the probiotic organisms, and their ORNs- Oligoribonucleotides, also called microRNAs. 30 billion CFU per tsp (5 grams).

Nutriceuticals– Fructo Borate, Vitamin B12, Vitamin D3, Folate, Chromium.

Suggested Dose:  Take one teaspoon a day mixed in a small glass of juice, such as pineapple or apple. You can mix with water, only if you are courageous, there are no sweetners, natural flavors, or any additives.  Take a look at the wonderful combination of natural organic ingredients.  A daily booster any time of the day or night.

Later this week in our Forward Thinking newsletter we will continue to discuss the new scientific thinking and research on longevity and health.

References

Caprara, G. (2018). Diet and longevity: The effects of traditional eating habits on human lifespan extension. Mediterranean Journal of Nutrition and Metabolism, (Preprint), 1-34. Abstract

Calder, P. C., Bosco, N., Bourdet-Sicard, R., Capuron, L., Delzenne, N., Doré, J., … & Visioli, F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing research reviews40, 95-119. Article

Devi, S. A., & Sekhar, S. R. (2018). Antiaging Interventions: An Insight into Polyphenols and Brain Aging. In Molecular Basis and Emerging Strategies for Anti-aging Interventions(pp. 281-295). Springer, Singapore. Abstract

Donoiu, I., Militaru, C., Obleagă, O., Hunter, J. M., Neamţu, J., Biţă, A., … & Rogoveanu, O. C. (2018). Effects of Boron-Containing Compounds on Cardiovascular Disease Risk Factors–A Review. Journal of Trace Elements in Medicine and Biology. Abstract

Filosa, S., Di Meo, F., & Crispi, S. (2018). Polyphenols-gut microbiota interplay and brain neuromodulation. Neural regeneration research13(12), 2055. Article

Fontana, L., Kennedy, B. K., Longo, V. D., Seals, D., & Melov, S. (2014). Medical research: treat ageing. Nature News511(7510), 405. Article

Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology4(3), 308-319. Article

Holscher, H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes8(2), 172-184. https://doi.org/10.1080/19490976.2017.1290756

Jin, K., Simpkins, J. W., Ji, X., Leis, M., & Stambler, I. (2015). The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population. Aging and disease6(1), 1. Article

Le Couteur, D. G., Solon-Biet, S., Wahl, D., Cogger, V. C., Willcox, B. J., Willcox, D. C., … & Simpson, S. J. (2016). New Horizons: Dietary protein, ageing and the Okinawan ratio. Age and ageing45(4), 443-447. Article

Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., … & Aryee, M. (2012). A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The lancet380(9859), 2224-2260. https://doi.org/10.1016/S0140-6736(12)61766-8

Mykytyn, C. E. (2006). Anti-aging medicine: A patient/practitioner movement to redefine aging. Social Science & Medicine62(3), 643-653. https://doi.org/10.1016/j.socscimed.2005.06.021

Nadon, N. L., Strong, R., Miller, R. A., Nelson, J., Javors, M., Sharp, Z. D., … & Harrison, D. E. (2008). Design of aging intervention studies: the NIA interventions testing program. Age30(4), 187-199. https://link.springer.com/article/10.1007/s11357-008-9048-1

Seidelmann, S. B., Claggett, B., Cheng, S., Henglin, M., Shah, A., Steffen, L. M., … & Solomon, S. D. (2018). Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. The Lancet Public Health3(9), e419-e428. Article

World Health Organization [WHO]. (2014). Twelfth general programme of work: Not merely the absence of disease. Article

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

In this fascinating website you can watch the numbers of births and the number of deaths growth in real time.  See Current World Population.  With the increasing numbers of people reaching sennescense and the mounting pandemic of chronic degenerative diseases, we need a sea-change in how we feed ourselves, to one that brings healthy longevity.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

The No. 7 Systemic Booster:  The New Longevity is here!

Dr. Dohrea Bardell’s chapter on chronic illness in Living Well, Dying Well (2018) emphasizes the global epidemic of chronic diseases, it has become the new norm (see Green Facts). Hence, No 7 is advanced with ingredients that are more important than ever.  We will discuss the how next week.

The No. 7 Systemic Booster: The New longevity is designed to boost healthy functionality in every system of our body. The formula is elegant and powerful, providing special phytonutrients, probiotics, nutraceuticals and plant fiber to lower inflammation, to detox, to build up the immune system, to support the gut’s eco-system, and to turn on our longevity genes.

No7_ 8.15.18
Suggested Dose:  Take one teaspoon a day mixed in a small glass of juice, such as pineapple or apple. You can mix with water, only if you are courageous, there are no sweetners, natural flavors, or any additives.  Take a look at the wonderful combination of natural organic ingredients.  A daily booster any time of the day or night.

What is in the mix?

Phytonutrients– Organic strawberry, raspberry, blueberry, tart cherry, elderberry, cranberry, apple extract, pineapple, beet, kale leaves, spinach leaves, broccoli florets.

BioImmersions Probiotic Super Blend:  The proprietary blend includes: Probiotics-Bifidobacterium longum, Lactobacillus casei, Lactobacillus acidophilus, Lactobacillus bulgaricus, Streptococcus thermophilus; Prebiotics-Inulin from Chicory root; Supernatant-nutritional metabolites from each of the probiotic organisms, and their ORNs- Oligoribonucleotides, also called microRNAs. 30 billion CFU per gram.

Nutriceuticals– Fructo Borate, Vitamin B12, Vitamin D3, Folate, Chromium.

References

Bardell, D. (2018). Living with chronic illness: Better health through lifestyle medicine. In Stevens-Long, J., Bardell, D., Living Well, Dying Well.  Fielding University Press.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The data in Living Well Dying Well (2018) present an alarming picture:

Today, chronic diseases are the world’s biggest killers, responsible for an estimated 35 million deaths each year. That’s 60% of all deaths globally. Among those over 65 in the United States, 85% suffer from one or two chronic diseases…. Chronic diseases are no longer isolated in the aging population.  Among children under 17, nearly a quarter have one or more chronic diseases,and nearly half of adults aged 18 to 64 have one or more chronic illnesses, with 20% of this adult group coping with two or more such condition. (p. 119-120)

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

Our famous High ORAC Synbiotic is now 10 times more potent. What’s new?

HO PhotoFirst, we added our new advanced Probiotic Super Blend, naturally occuring whole probiotics with their Supernatant and ORNs (oligoribonucleotides). The five pedigreed lactic acid bacterial strains in our Supernatant Synbiotic are excellent as post antibiotic care.

We also added the supernatant of each of these five effective probiotics: The supernatant includes their healing metabolites, enzymes, vitamins, lactic acid, bacterocins, biosurfactants, bile salt hydrolase, and so much more.

The full-spectrum antioxidant activity component of High ORAC Synbiotic is a property of its new proprietary blend of fruit, berries and bioflavonoids.  A blend that successfully reduces the five major categories of free radicals- the hydroxyl, peroxyl, peroxynitrite, singlet oxygen, and superoxide anion.  It is standardized to a minimum total ORAC score of 40,000 umol Trolox equivalent (TE) per gram as measured by the ORAC 5.0 assay. That is 10 times more potent!

One capsule a day will do nicely.

Food Science

Studies are showing that dietary polyphenols contribute to the maintenance of intestinal health by preserving the gut microbial balance through the stimulation of the growth of beneficial bacteria such as Lactobacilli and Bifidobacteria while inhibiting that of pathogenic bacteria.

Dueñas et al.’s (2015) study, A survey of modulation of gut microbiota by dietary polyphenols, showed that the beneficial effects attributed to dietary polyphenols appear to be due more to phenolic metabolites formed in the gastrointestinal tract, mainly derived from the action of gut bacteria than to the original forms found in food.

This all occurs in the colon where the growth of good bacterial friends is enhanced by polyphenols while at the same time the beneficial attributes of the polyphenols are made possible by their reduction into shorter chain lengths by the enzymes of these good bacteria.  Making their antioxidant, antimicrobial, anti-inflammtory, healthy aging, cell signaling effects more bioavailable throughout the body.

Duda-Chodak et al. (2015) present possible pathways of polyphenol metabolism by intestinal bacteria and describe the diet-derived bioactive metabolites produced by gut microbiota, with a particular emphasis on polyphenols and their potential impact on human health.

We will talk much more about this in coming Forward Thinking newsletters.

References

Dueñas, M., Muñoz-González, I., Cueva, C., Jiménez-Girón, A., Sánchez-Patán, F., Santos-Buelga, C., … & Bartolomé, B. (2015). A survey of modulation of gut microbiota by dietary polyphenols. BioMed research international2015. https://www.hindawi.com/journals/bmri/2015/850902/

Duda-Chodak, A., Tarko, T., Satora, P., & Sroka, P. (2015). Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review. European journal of nutrition54(3), 325-341. https://link.springer.com/article/10.1007/s00394-015-0852-y

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Game Changers  will introduce the world of elite athletes, special ops soldiers, visionary scientists, cultural icons and everyday heroes.  Each on a mission to create a seismic shift in the way we eat and live.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved