Dear Friends

Chronic Disease is the new norm.  We see it all around us:  obesity, metabolic syndrome, fatty liver, diabetes, CVD, cancer, COPD, asthma, Alzheimer’s, Parkinson’s, autism, IBD, IBS,  auto immune disease, arthritis, UTI, and many more.

Doctors, you are our heroes on the frontline in the battle for your patients’ health, and for helping them to prevent their occurrence in the first place.

Key finding in research for the root cause of these chronic illnesses: a continual low-grade inflammation (LGI), termed by scientists as “inflammageing” (Franceschi & Campisi, 2014).

Therapeutic Food Supplements were designed with powerful plant polyphenols, pedigreed probiotic strains  (with their metabolites and microRNAs), and key nutraceuticals to supports the reduction of LGI.  The results are easily measured:  lowering inflammatory markers.

Summary of the Therapeutic Food Offering:

Polyphenol products:  Garlic (antimicrobial, blood pressure regulation), Blueberry Extract (brain and nerve regeneration), Glucosinolates & Sulforaphanes (liver support), Chlorella (absorption of heavy metals and toxins), Be Regular (fiber from ancient seeds – a must have), and Phyto Power (DNA integrity).

Probiotic Products: Supernatant Synbiotic, and Original Synbiotic. Both powerfully effective for GI health

Probiotic + Polyphenols: High ORAC Synbiotic (post antibiotic therapy), Beta Glucan Synbiotic (Cardiovascular and GI support), No. 7 Systemic Booster (designed to combat the root cause of chronic illnesses), and Cranberry Pomegranate Synbiotic (UTI, and prostate support).

Nutraceuticals:  Fructo Borate Complex (bone and joints), Chromium (blood sugar control), Energy (plant ultra minerals), No. 7 (B12, Folate, chromium, D3, and Fructo Borate), Weight-Less (7 keto).

Nutraceuticals + Polyphenols:  Energy (increase ATP levels), Weight-less (weight loss and blood sugar control), and Chromium with high active Beet Root (blood sugar control, increase circulation), No 7 Systemic Booster.

All of our plant materials are eco-farmed, or wild-crafted, selected for their exceptional high-actives, many of which we standardize.  There are no excipients in our Therapeutic Food Supplement (e.g. flowing agents, sweeteners, natural flavors, emulsifiers, etc.).  We are purists in this regard, wanting to give you absolutely the strongest possible natural product for you restoring health.

References:

  • Boivin et al. (2009). Antiproliferative and antioxidant activities of common vegetables: A comparative Study. Food Chemistry; 112(20): 374-380. Article
  • Calder, P. C., Bosco, N., Bourdet-Sicard, R., Capuron, L., Delzenne, N., Doré, J., … & Visioli, F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing research reviews40, 95-119. Article
  • Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences69(Suppl_1), S4-S9. Article

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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BioImmersion Therapeutic Food Supplements are certainly a strong tool to facilitate the healing of our bodies; a healthy diet and a clean environment are its necessary partners.  How do we create a healthy environment? A healthy biosphere?  Biomimicry Institute provides some enlightened answers.

 

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

Anderson et al.  (2011) demonstrated the powerful anti-obesity effects of rose hip in their research entitled, Rose hip exerts antidiabetic effects via a mechanism involving downregulation of the hepatic lipogenic program.

Two different parts of the 2011 research provided a window into rose hip’s weight lowering power.

In Study A, labeled the preventative study, 20 mice were divided into two groups, the control group and the rose hip fed group. Both groups were fed the high-fat diet during the 20 week trial but  the rose hip group showed a markedly lower body weight gain compared to the control group: 7.1 grams vs. 17.1 grams.

In Study B, labeled the intervention study, 10 mice were divided into two groups, the control group and the rose hip fed group. Both groups were fed the same low-fat diet during their 10 week trial but the control group kept gaining body weight while the rose hip group immediately started to lose weight. By at the end of the study, the difference in the body weight of the two groups was pronounced with the rose hip group average weight being 28.6 grams and the control being 38.5 grams.


Rose Hip Obesity Graph

Anderson et al. (2011) summarized that high doses of rose hip are capable of both preventing and reversing the increase in body weight.  Another dramatic beneficial aspect of rose hip supplementation:  Hepatic lipids were reduced by >50%  following the rose hip intake as a result of down-regulation of the hepatic lipogenic program. The researchers theorized that this may represent a major mechanism underlying the improvement in insulin sensitivity and glucose tolerance.  Finally, they concluded that their results show great promise for the use of more moderate doses of rose hip to improve glucose tolerance and lower body weight in humans.

Phyto Power is a polyphenolic powerhouse comprised of several species of wildcrafted Rose hips, Blueberries, and Dandelions, harvested in the wilds of Alaska at the peak of their phytonutrient potential.

Recommended dose:  2 capsules daily

References:

  • Andersson, U., Henriksson, E., Strom, K., Alenfall, J., Goransson, O., Holm, C. (2011). Rose hip exerts antidiabetic effects via a mechanism involving downregulation of the hepatic lipogenic program. Am J Physiol Endocrinol Metab, 300, E111–121.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Type 2 diabetes is strongly associated with obesity; 90% of all patients with type 2 diabetes are overweight or obese.  Both type 2 diabetes (T2D) and obesity are also strongly associated with nonalcoholic fatty liver disease (NAFLD), the most common liver disease worldwide.  More than 70% of subjects with T2D and/or obesity are affected with NAFLD (Anderson et al., 2011).

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

Alzheimer’s has moved up to the number three cause of death in the United States just under cancer and heart disease (NIH- National Institute of Aging, 2019).

Julien et al. (2009) compared the concentration of SIRT1 in the brains of AD patients and controls. In the first group of 19 patients and 22 controls,  a significant reduction of SIRT1 in the parietal cortex of AD patients was found.  Further analyses in a second cohort of 36 subjects confirmed that cortical SIRT1 was decreased in AD but not in individuals with mild cognitive impairments.  A significant relationship between SIRT1 levels and global cognition scores proximate to death was also found. Collectively, their results indicate that loss of SIRT1 is closely associated with the accumulation of amyloid-beta and tau in the cerebral cortex of persons with AD.  Furthermore, autopsies of Alzheimer’s victims reveal that loss of sirtuin enzyme activity is closely associated with the accumulation of the plaques and tangles.

Plants (fruits, berries, veggies, and greens) contain key phytonutrients, namely polyphenols. In research, an increasing number of polyphenols are being found to turn on a family of our anti-aging genes called sirtuins.  Sirtuins, particularly SIRT1 expression, is shown to reduce and eliminate amyloid-B and tangles, two protein derangements that are symptomatic of Alzheimer’s.   High heat cooked meats and fats create a molecule called advanced glycation end products (AGEs) which when present in the blood turn off the sirtuin gene expression, thereby turning off the expression of these anti-aging genes (Julien et al., 2009).

The Therapeutic Food Supplements  boost our body with key plant polyphenols that turn on the sirtuins.  Each of the four products is designed to supply ample amounts of phytonutrients and in particular polyphenols such as resveratrol, quercetin, and catechins to  enhance brain function.

For preventing cognitive decline and beginning stages of dementia, add to your protocol the High ORAC Synbiotic  with standardized high levels of  resveratrol and quercetin.

For a progressive decline and Alzheimer’s, add to the High ORAC a more robust protocol of powerful polyphenols to regenerate neurons in the brain:

References:

  • Grabowska, W., Sikora, E., & Bielak-Zmijewska, A. (2017). Sirtuins, a promising target in slowing down the ageing process. Biogerontology,18(4), 447-476.
  • Julien, C., Tremblay, C., Emond, V., Lebbadi, M., Salem Jr, N., Bennett, D. A., & Calon, F. (2009). Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease. Journal of Neuropathology & Experimental Neurology, 68(1), 48-58.
  • Uribarri, Jaime, Sandra Woodruff, Susan Goodman, Weijing Cai, Xue Chen, Renata Pyzik, Angie Yong, Gary E. Striker, and Helen Vlassara. (2010). “Advanced glycation end products in foods and a practical guide to their reduction in the diet.” Journal of the American Dietetic Association110, no. 6: 911-916.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Our diet is a major factor in whether we succumb to Alzheimers or not.  Eating primarily a whole-foods plant-based diet with meat and fat being more like a condiment puts the odds highly in one’s favor on not becoming its victim (Uribarri et al., 2010).

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Doctor

Aging is characterized by a condition of rising levels of free radicals that generates increasing cellular senescence.

Only recently has aging itself been viewed as a treatable condition, with an etiology related to excessive ROS levels that lead to cellular senescence, a process by which cells enter a permanent state of cell cycle arrest. Although senescent cells lost their proliferative capacity, they still are able to secrete a range of proinflammatory molecules through the senescence associated secretory phenotype (SASP).

Patients with coronary artery disease show increased expression of the proinflammatory molecules MCP-1, IL-6, IL-1β and tumor necrosis factor α (TNF-α), all of which are secreted by senescent cells through the SASP.

In Serino and Salazar’s 2019 review, Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease, they discuss molecular mechanisms by which polyphenols improve anti-oxidant capacity, mitochondrial function and autophagy, while reducing oxidative stress, inflammation and cellular senescence in vascular smooth muscle cells (VSMCs) and endothelial cells (ECs). They also  discuss the therapeutic potential of polyphenols in reducing the effects of the SASP and the  incidence of CVD.

The following Therapeutic Food protocol makes sense in light of Serino and Salazar’s research. (See also Food Science below)

Therapeutic Food Support:

Suggestions:  Add one tsp No. 7 to your smoothy, or to your shot glass of diluted juice add one tsp No. 7 and swig down the Glucosinolate capsule and 2 capsule of Phyto Power.   Try it for a couple of months and see how you feel.

Food Science:

Lai et al. (2015) reported that total fruit intake (g/day) derived from a 217-item Food Frequency Questionnaire was obtained from 30,458 women (aged 35–69 years) at baseline from 1995–1998., the richest sources of phenolic compounds, correlated with improved cardiovascular health with an estimated 6–7% reduction in deaths from CVDs for every 80 g portion. This study concluded that total fruit intake rather than intake of a specific type of fruit is protective against CVD. In terms of specific types of fruits, commonly researched varieties include berries, such as blackberries, raspberries, black raspberries and blueberries, grapes, citrus fruit, pomegranates, strawberries and apples. These fruits are rich in polyphenols like flavanols, flavonols, anthocyanins, procyanidins, sterols, carotenoids, and hydroycinnamic acids.

The Therapeutic Food Supplement protocol above provides a rich diversity of high active fruits and vegetables.

References:

  • Serino, A., & Salazar, G. (2019). Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease. Nutrients,11(1),
  • Lai, H. T. M., Threapleton, D. E., Day, A. J., Williamson, G., Cade, J. E., & Burley, V. J. (2015). Fruit intake and cardiovascular disease mortality in the UK Women’s Cohort Study. European journal of epidemiology, 30(9), 1035-1048.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Kaiser Permantente has published a remarkable nutritional update for their 15,000 physicians who care for their 10 million members.  Kaiser is now telling doctors that healthy eating may best be achieved with a plant-based diet, defined as a regiment that “encourages whole, plant-based foods and discourages meats, dairy and eggs as well as all refined and processed junk food (Tuso, 2013).”

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Doctor

Over the next week or two we will focus on Heart Disease, still the No. 1 killer in the developed world. (WHO, 2016).

No.1 Cause of Death

The No. 1 killer in the industrial world is Heart Disease.  How can Therapeutic Food help to prevent HD?

In industrialized countries isolated systolic hypertension (ISH) increases steeply with age. Many Americans over the age of 60 have ISH, which is increasingly recognized as a cardiovascular risk. Several studies have shown the strong association between ISH and stroke, kidney failure, cardiovascular morbidity and mortality (Gasowski et al, 2002; Vaccarino et al, 2001).
Reversing or stabilizing the increased arterial stiffness associated with age and disease by targeting any or all of its causes provides of a number of promising new approaches to treatment of systolic hypertension and its sequel, the main causes of mortality and morbidity (Greenwald SE, 2007).

Therapeutic Food supplements magnify the protective benefits of key phytonutrients that support the reduction of ISH.

Therapeutic Food protocol to support protection from ISH:

  • Phyto Power, wild crafted– 2 capsules BID.
  • Be Regular– 2 heaping tbl taken as a meal replacement three times weekly.
  • No. 7 Systemic Booster– 1 tsp at breakfast
  • Beta Glucan High Potency Synbiotic– 1 heaping tbl BID before 2 largest meals.
  • Chromium, Bio-organic with Beet– 1 capsule BID.

Food Science:  In this email we’ll focus on the Phyto Power

Phyto Power copy

Research has shown that the catechin family of flavonoids provide protective phytonutrients particularily from catechin, epicatechins and epigallocatechin gallate.

Endothelial dysfunction, a prognostically relevant key event in atherosclerosis, is characterized by a decreased bioactivity of nitric oxide (NO) and impaired flow-mediated vasodilation (FMD).  Schroeter et al., (2006) showed in healthy male adults that the ingestion of flavanol-rich cocoa was associated with acute elevations in levels of circulating NO species, an enhanced FMD response of conduit arteries, and an augmented microcirculation.

Nagao et al., (2007) observed, in a protocol sample of 240 subjects, that green tea extract high in catechins reduces body fat and cardiovascular risks including a decrease in systolic blood pressure. Low-density lipoprotein cholesterol was also decreased to a greater extent in the catechin group.

Lorenz et al., (2007) investigated the effect of milk in preventing the beneficial effects of tea relative to vascular protection, and found that casein in milk binds to catechins inhibiting their beneficial functioning as antioxidants.  Their conclusion was that milk counteracts the favourable health effects of tea on vascular function.

The wilds of Alaska provide an amazing environment for powerful plants and berries— fertile volcanic ash soil, and a harsh environment that challenges plants to put out high levels of phenols (e.g. flavonoids) to protect themselves.

Notice the different between an Alaskan rosehip and the typical Europe rosehip (dog-rose) in terms of their phytonutrient load.

Flavonoids

  • Quercetin- 10.50 (Alaskan rosehip) verses 1.05 (European rosehip) in mg/g.
  • Hyperoside- 3.03 verses 4.30
  • Kaempferol- 1.62 verses 0.00
  • Isoquercitin- 0.78 verses 3.51
  • Naringenin- 0.26 verses 0.15
  • Rutin- 0.16 verses 0.67
  • Nothofagrin- 0.26 verses 0.07
  • Luteolin- 0.02 verses 0.01
  • Biochanin A- 0.02 verses 0.00

Catechins

  • Catechin- 72.5 verses 35.70
  • Epicatechin- 67.50 verses 33.70
  • gallocatechin- 0.93 verses 0.86
  • epicatechin gallate- 0.45 verses 0.15
  • catechin gallate- 0.25 verses 0.02.

Organic Acids

  • Ellagic acid- 48.30 verses 5.25
  • Gallic acid- 7.85 verses 0.14
  • p- Coumaric acid- 1.54 verses 0.16
  • Protocatachuic acid- 0.97 verses 0.18
  • Caffeic acid- 0.38 verses 0.00
  • Chlorogenic acid- 0.30 verses 0.05.
  • Salicylic acid- 0.22 verses 0.14
  • Fefulic acid- 0.06 verses 0.09

Vitamins

  • Vitamin C- 25.00 verses 10.00
  • Vitamin B3- 1.09 verses 0.19
  • Vitamin B2- 0.08 verses 0.11
  • Vitamin B1- 0.03 verses 0.01
  • Vitamin B6- 0.01 verses 0.00.

Carotenoids

  • Lycopene- 4.89 verses 2.98
  • b-Carotene- 1.15 verses1.53
  • Lutein- 0.21 verses 0.00
  • Zeaxanthin- 0.17 verses 0.19.

Phyto Power’s Alakan Rosehip provides high amount of catechins.  Two capsules gives one the equivalent of two squares of dark chocolate in catechins without the sugar.

References:

  • Dower et al. (2015). Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized double-blind, placebo-controlled, crossover trial. Am J Clin Nutr; 101(5): 914-21.
  • Engler at al. (2004). Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. J Am Coll Nutr; 23:197-204.
  • Greenwald SE. (2007). Ageing of the conduit arteries. J Pathol; 211(2): 157-172.
  • Lorenz et al. 2007. Addition of milk prevents vascular protective effects of tea. European Heart Journal; 28(2): 2219-2223.
  • Nagao et al. (2007). A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity; 15: 1473-1483.
  • Schroeter et al. (2006). Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. PNAS; 103:1024-1029.
  • Tuso et al. (2013) Nutritional Update for Physicians: Plant-Based Diets.
  • WHO (World Health Organization) Cancer Statistics, Sept. (2016).

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Kaiser Permantente has published a remarkable nutritional update for their 15,000 physicians who care for their 10 million members.  Kaiser is now telling doctors that healthy eating may best be achieved with a plant-based diet, defined as a regiment that “encourages whole, plant-based foods and discourages meats, dairy and eggs as well as all refined and processed junk food (Tuso, 2013).”

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©2005 – 2019 BioImmersion Inc. All Rights Reserved