Cruciferous Sprouts

Dear Doctor

Aging is characterized by a condition of rising levels of free radicals that generates increasing cellular senescence.

Only recently has aging itself been viewed as a treatable condition, with an etiology related to excessive ROS levels that lead to cellular senescence, a process by which cells enter a permanent state of cell cycle arrest. Although senescent cells lost their proliferative capacity, they still are able to secrete a range of proinflammatory molecules through the senescence associated secretory phenotype (SASP).

Patients with coronary artery disease show increased expression of the proinflammatory molecules MCP-1, IL-6, IL-1β and tumor necrosis factor α (TNF-α), all of which are secreted by senescent cells through the SASP.

In Serino and Salazar’s 2019 review, Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease, they discuss molecular mechanisms by which polyphenols improve anti-oxidant capacity, mitochondrial function and autophagy, while reducing oxidative stress, inflammation and cellular senescence in vascular smooth muscle cells (VSMCs) and endothelial cells (ECs). They also  discuss the therapeutic potential of polyphenols in reducing the effects of the SASP and the  incidence of CVD.

The following Therapeutic Food protocol makes sense in light of Serino and Salazar’s research. (See also Food Science below)

Therapeutic Food Support:

Suggestions:  Add one tsp No. 7 to your smoothy, or to your shot glass of diluted juice add one tsp No. 7 and swig down the Glucosinolate capsule and 2 capsule of Phyto Power.   Try it for a couple of months and see how you feel.

Food Science:

Lai et al. (2015) reported that total fruit intake (g/day) derived from a 217-item Food Frequency Questionnaire was obtained from 30,458 women (aged 35–69 years) at baseline from 1995–1998., the richest sources of phenolic compounds, correlated with improved cardiovascular health with an estimated 6–7% reduction in deaths from CVDs for every 80 g portion. This study concluded that total fruit intake rather than intake of a specific type of fruit is protective against CVD. In terms of specific types of fruits, commonly researched varieties include berries, such as blackberries, raspberries, black raspberries and blueberries, grapes, citrus fruit, pomegranates, strawberries and apples. These fruits are rich in polyphenols like flavanols, flavonols, anthocyanins, procyanidins, sterols, carotenoids, and hydroycinnamic acids.

The Therapeutic Food Supplement protocol above provides a rich diversity of high active fruits and vegetables.

References:

  • Serino, A., & Salazar, G. (2019). Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease. Nutrients,11(1),
  • Lai, H. T. M., Threapleton, D. E., Day, A. J., Williamson, G., Cade, J. E., & Burley, V. J. (2015). Fruit intake and cardiovascular disease mortality in the UK Women’s Cohort Study. European journal of epidemiology, 30(9), 1035-1048.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Kaiser Permantente has published a remarkable nutritional update for their 15,000 physicians who care for their 10 million members.  Kaiser is now telling doctors that healthy eating may best be achieved with a plant-based diet, defined as a regiment that “encourages whole, plant-based foods and discourages meats, dairy and eggs as well as all refined and processed junk food (Tuso, 2013).”

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Doctor

The ageing of our society presents an increasing number of older patients, individuals who are dealing with a whole host of chronic diseases, including cancer, ischemic heart disease, stroke, type 2 diabetes, Alzheimer’s disease, and others (Jin et al. 2015).

Researchers are finding that unchecked chronic low-grade inflammation (LGI) is a major etiological driver.  According to the WHO, Harvard, the Mayo Clinic, NIH, and other research institutions,  dietary factors play a major role in the reduction of these morbidities (Calder et al., 2017).

The No. 7 Systemic Booster:  The New Longevity is a very powerful anti-inflammatory, the root cause of chronic illnesses.

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The daily dose is one tsp a day.  It has a bitter chocolate taste (there is no chocolate in it). Therefore mix a tsp of No. 7 with your favorite healthy juice.  Make it a jiggers shot, or mix in a large glass and sip slowly.  It is delicious and you will feel its energy giving power.

A powerful combination is to make your drink and then take one capsule of the Energy and one capsule of the Glucosinolate and Sulforaphane for liver support.

ENERGY

 

G and S

 

References:

  • Calder, P. C., Bosco, N., Bourdet-Sicard, R., Capuron, L., Delzenne, N., Doré, J., … & Visioli, F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing research reviews40, 95-119. Article
  • Jin, K., Simpkins, J. W., Ji, X., Leis, M., & Stambler, I. (2015). The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population. Aging and disease6(1), 1. Article

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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The No 7 Longevity encompasses a great deal of research into better health. The scientific community has much more to discover, yet many of the findings do show a clear path toward health that is not riddled by chronic conditions that can be supported by a plant-based diet of whole foods, a cleaner home and office environments, exercise, toxic free personal and home cleaning products, organic or pesticides & herbicides free foods, and clean, researched based supplementations (see Living Well – Dying Well , Chapter 8).

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

We are excited to announce our new and incredibly potent: organic broccoli cruciferous sprout. Our Glucosinolates & Sulforaphanes is a powerhouse, providing a four fold increase in the phase 2 enzymes inducing and cancer preventing molecules for which it is named.

G and S

Notice that the label above guarantees a Glucosinolate level of 15,000 ppm, a Glucoraphanin level of 10,000 ppm and a Sulforaphane potential of 4,000 ppm.  However, as you can see in the Certificate of Analysis below, the actual levels of these three most important ingredients are much higher, with the Glucosinolates at 21,359 ppm, the Glucoraphanins at 19,407 ppm, and the Sulforaphane yield at 8,733 ppm.  Our old beloved Cruciferous Sprouts product offered a 1500 ppm sulforaphane potential yield.

Organic Broc Sprout CofA

Recommended dose:  one to two capsules daily. Excellent before bed for liver detox.

Sulforaphane (SF) is a phytochemical that displays both anticarcinogenic and anticancer activity. SF modulates many cancer‐related events, including susceptibility to carcinogens, cell death, cell cycle, angiogenesis, invasion and metastasis.   Zhang and Tang (2007) review its discovery and development as a cancer chemopreventive agent.

The preponderance of evidence available from in vitro, animal, and human studies supports the association of sulforaphane with phase II enzyme inductions.  Broccoli sprouts are the richest source of glucoraphanin which is the direct precursor to sulforaphane.  Since broccoli sulforaphane is one of the most potent inducers of phase II enzymes, exploration into broccoli’s impact on other areas of human health, such as cardiovasucular health and upper airway immunity, has been suggested (James et al., 2012).

In Qidong, China, a region where exposures to food-and air-borne carcinogens has been considerable, clinical trials indicate that interventions with well characterized preparations of broccoli sprouts may enhance the detoxication of aflatoxins and air-borne toxins, which may in turn attenuate their associated health risks including cancer in exposed individuals (Kensler et al., 2012).

We will continue to discuss this powerhouse product in our next email.

References:

  • James, D., Devaraj, S., Bellur, P., Lakkanna, S., Vicini, J., & Boddupalli, S. (2012). Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli. Nutrition reviews, 70(11), 654-665.
  • Kensler, T. W., Egner, P. A., Agyeman, A. S., Visvanathan, K., Groopman, J. D., Chen, J. G., … & Talalay, P. (2012). Keap1–nrf2 signaling: a target for cancer prevention by sulforaphane. In Natural Products in Cancer Prevention and Therapy(pp. 163-177). Springer, Berlin, Heidelberg.
  • Zhang, Y., & Tang, L. (2007). Discovery and development of sulforaphane as a cancer chemopreventive phytochemical. Acta pharmacologica Sinica, 28(9), 1343-1354.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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The Environmental Working Group is a most important organization to get to know.  Their mission is to empower people to live healthier lives in a healthier environment. With breakthrough research and education, they drive consumer choice and civic action.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

What’s new at BioImmersion?

September 18, 2018

Dear Friends

What’s new at BioImmersion?   Plenty!  And, we are very excited to share the good news this week.  First, we are almost done updating all the labels.  Thank you, Hovie Hawk, our amazing website and label art designer who we think has done a beautiful job! Secondly, we continually seek out and incorporate into our formulas more powerful plant materials and bio-available nutriceuticals. Our proprietary blends of naturally occuring, whole probiotics, complete with their supernatant and ORNs are better than ever. We have been working in the last two years with our scientists and researchers to advance and update our formulations according to the latest scientific findings.

As ususal, we are not trendy or commercial – we hold firm to scientific research and formulate accordingly.

Here is a glimpse of four advanced formulas.  I’ll expand on them in the coming weeks.

(1)  GLUCOSINOLATES & SULFORAPHANES:  Organic Broccoli Sprouts

  • This product advances the Cruciferous Sprout Complex, with six times  the potency of sulforaphane potential.
  • Glucosinolate is the precursor molecule to glucoraphanin which is the precursor to sulforaphanes.
  • Sulforaphes enhance detoxication of aflatoxins, the most dangerous of mold toxins, and air-borne pollutions, and is a major inducer of phanse 2 detoxication enzymes for liver detox.

G and S


(2)  ENERGY:  Plant Ultra Minerals with Apple Extract

  • Our proprietary blend of ancient plant minerals and apple extract has been clinically testedto increase ATP levels by enhancing mitochondrial ATP production.
  • Resistance training with healthy males saw increases in their strength and endurance while taking this product.
  • Supplementation with our Energyblend of ancient peat minerals and apple extract enhanced resistance training-induced skeletal muscle hypertrophy without affecting fat mass or blood chemistry of rhese healthy males.

ENERGY

 

(3)  No. 7 Systemic Booster:  The New Longevity

  • The new longevity: In research, aging is linked to a variety of chronic illnesses that occur due to a continual inflammatory state in the body, which accelerates stem cells’ deterioration and ultimately lessens our ability to regenerate. 
  • The No 7 combination of Polyphenols (from high active berries, fruit, veggies, and greens), Fibers, Prebiotic, B12, Fructo Borate, Folate, Chromium, and the new blend of naturally occurring whole Probiotics with their Supernatant and ORNs offer potent calming nutrients and rejuvination.
  • The No 7 boosts many systems in the body: the GI Tract, Urogenital, Osteo-skeletal, Cardiovascular, Brain and Neurological, Detoxification, Metabolic, Digestive, and Energy.

No7_ 8.15.18

 

(4)  High ORAC Synbiotic:  Post Antibiotic Care

  • The High ORAC is 10 times more potent with Total ORAC of 40,000ppm! The advanced formula’s Polyphenols re-energize our bodies by boosting nitric oxide levels in the blood; stimulate antioxidant activity while reducing ROS; improve cellular oxygen consumption.
  • The new naturally occuring whole probiotics with Supernatant and ORNs create a more acidic ph balance in the gut, allowing a better growth of good organisms while creating an antimircrobial effect that protects the GI tract membrane from opportinistic pathogen- e.g., Candida.
  • Since antibiotics often unbalance the microbiome (GI Tract) resulting in overgrowth of yeast in the gut and vagina, we have chosen plant extracts that have antimicrobial properties, and together with the probiotic, reduce pathogenic populations, calm the GI, and restore normal balance to the microbiome.

HOS _9.15.18

 

References:

  • Zhang, Y., Kensler, T. W., Cho, C. G., Posner, G. H., & Talalay, P. (1994). Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proceedings of the National Academy of Sciences, 91(8), 3147-3150.
  • Zhang, Y., & Tang, L. (2007). Discovery and development of sulforaphane as a cancer chemopreventive phytochemical. Acta pharmacologica Sinica, 28(9), 1343-1354.
  • Don James, Sridevi Devaraj, Prasad Bellur, Shantala Lakkanna, John Vicini and Sekhar Boddupalli, Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced‐glucoraphanin broccoli, Nutrition Reviews, 70, 11, (654-665), (2012).
  • Joy, J. M., Falcone, P. H., Vogel, R. M., Mosman, M. M., Kim, M. P., & Moon, J. R. (2015). Supplementation with a proprietary blend of ancient peat and apple extract may improve body composition without affecting hematology in resistance-trained men. Applied Physiology, Nutrition, and Metabolism, 40(11), 1171-1177.
  • Joy, J. M., Vogel, R. M., Moon, J. R., Falcone, P. H., Mosman, M. M., Pietrzkowski, Z., … & Kim, M. P. (2016). Ancient peat and apple extracts supplementation may improve strength and power adaptations in resistance trained men. BMC complementary and alternative medicine, 16(1), 224.
  • Moco, S., Martin, F. P. J., & Rezzi, S. (2012). Metabolomics view on gut microbiome modulation by polyphenol-rich foods. Journal of proteome research11(10), 4781-4790.http://pubs.acs.org/doi/abs/10.1021/pr300581s.
  • Duda-Chodak, A., Tarko, T., Satora, P., & Sroka, P. (2015). Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review. European journal of nutrition54(3), 325-341. https://link.springer.com/article/10.1007/s00394-015-0852-y
  • Federico, A., Morgillo, F., Tuccillo, C., Ciardiello, F., & Loguercio, C. (2007). Chronic inflammation and oxidative stress in human carcinogenesis. International Journal of Cancer, 121(11), 2381-2386.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Federico et al. in their research paper, Federico, A., Morgillo, F., Tuccillo, C., Ciardiello, F., & Loguercio, C. (2007). Chronic inflammation and oxidative stress in human carcinogenesis.  International Journal of Cancer, 121(11), 2381-2386, state that a wide array of chronic inflammatory conditions predispose susceptible cells to neoplastic transformation.

Inflammatory condition occurs when the generation of free radicals and active inter-mediates in a system exceeds the system’s ability to neutralize and eliminate them.  Reactive intermediates of oxygen and nitrogen may directly oxidze DNA, or may interfere with DNA repair.

The above link takes you to this review which focuses on some of these intricate events by discussing the relationships occurring among oxidative/nitrosative/metabolic stress, inflammation and cancer.

You can see now when contemplating on the features and benefits of our products outlined above that they have major applications for this chronic inflammation condition and its down stream consequences.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Plants Heal

February 13, 2018

Dear Friends

Plants heal. A plant based diet centered around vegetable, fruits, grains, legumes, nuts, and seeds is now being promoted by Kaiser Permanente (the largest of Americas health care providers), the WHO (The World Health Organization), and Harvard Medical School.
Noncommunicable diseases (chronic diseases) are on the rise. According to our Dr. Dohrea Bardell, statistics on “our aging population project” that 6 out of 10 people will live with 1 to 5 different chronic illnesses. But that is not all, chronic diseases also affect our younger (0-18) and working-age (from 18-64) populations.
Plant based diets (vegetarian and vegan) have shown in research to prevent and even reverse noncommunicable diseases (NCDs) such as Metabolic Syndrome, Obesity, Diabetes, Heart Disease, Cancer and additionally Arthritis, and Neurological Disorders. More on that will be published in the joint project with Dr. Judy Stevens-Long and Dr. Dohrea Bardell later this year.

The following four BioImmersion products provide the essence of what these dietary regimes must give your body to support your body attaining health in old age.

Garlic: 1 capsule each day. Garlic is shown to not only fight colds/flu but to support the body against a variety of cancers.
Cruciferous Sprouts– 2 capsules a day before bed to support the liver’s ability to detox (phase II detox). Cruciferous vegetables are touted as the best preventative foods against cancer.
Phyto Power– 1-2 capsules daily taken in the morning to provide the brain with the best food for better thinking, regeneration of nerves, and prevent aging brain. The potent polyphenols also protect against a variety of cancers (blueberries and rose hips), offer anti inflammatory properties, and liver support (dandelion).

Beta Gluten High Potency Synbiotic– one heaping tablespoon taken before breakfast or dinner. One of the most potent probiotic product with 65 billion strong probiotic organisms, and our famous beta glucans with red beet root to lower cholesterol and support liver function. The beta glucans also are shown to support  prevention of variety of cancers.

As you can see, we revere plants and their power to heal our bodies.

Cancer Support

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

 

Green Facts:

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Choosing a healthy diet: Research studies link the emerging global pattern of metabolic syndrome and weight gain to the prevalence of Westernized diet of daily meats, dairy, eggs, simple and processed carbohydrates, and too much sugar (Chai et al., 2017; Azadbakht & Esmaillzadeh, 2009; Lutsey et al., 2008). Although there are conflicting views on dietary guidelines, many scientists and health organizations agree that a focus on whole food plant-based diet is the healthiest guideline for metabolic syndrome and weight loss (Yokoyama et al., 2017; Satija et al., 2017; Kahleova et al., 2017; Hever et al., 2017; Turner et al., 2017; UN Report, 2016; Wang et al., 2015; Tilman & Clark, 2014; WHO/FAO, 2003).*

 

The Plates, Pyramids, Planet report, compiled in collaboration with the Food Climate Research Network (FCRN) at the University of Oxford, concludes that a plant-based diet has many advantages for health and the environment (UN Report, 2016).*

The type and nature of carbohydrates that improve our metabolic health (obesity, cardiovascular, and diabetes) are comprised of whole plants with fiber (Wright et al., 2017). Whereas low carbs diets with high fat content is shown to increase metabolic syndrome (Lamont et al., 2017; UN Report, 2016).*

A diet that is 80-90% whole food plant-based is highly recommeded by many health organizations and medical universities around the world.


 

©2005 – 2018 BioImmersion Inc. All Rights Reserved