Cold and Flu Support

Dear Doctor

Novel strategies for controlling influenza are needed, especially for susceptible subpopulations such as those with chronic disease, or with chronic exposure to airborne pollutants.

Muller et al (2016) and Noah et al (2014) showed us, in their respective randomized double-blind trials, that eating broccoli sprouts can reduce viral loads for influenza, decrease virus-induced inflammation, and boost your antiviral natural killer cell activity.  The active molecule within broccoli sprouts that accomplishes this is sulforaphane.

Our Glucosinolates & Sulforaphanes is a powerhouse, providing a four-fold increase in the phase 2 enzymes inducing and cancer preventing molecules for which it is named.

GS FMore Powerful:  Notice that the label above guarantees a Glucosinolate level of 15,000 ppm, a Glucoraphanin level of 10,000 ppm and a Sulforaphane potential of 4,000 ppm. However, as you can see in the Certificate of Analysis below, the actual levels of these three most important ingredients are much higher, with the Glucosinolates at 21,359 ppm, the Glucoraphanins at 19,407 ppm, and the Sulforaphane yield at 8,733 ppm.  Our old beloved our Glucosinolates & Sulforaphanes product offered a 1500 ppm sulforaphane potential yield.

Organic Broc Sprout CofA

Recommended dose:  one to two capsules a day. Preferably on empty stomach AM/PM.

Sulforaphane (SF) is a phytochemical that displays both anticarcinogenic and anticancer activity. SF modulates many cancer‐related events, including susceptibility to carcinogens, cell death, cell cycle, angiogenesis, invasion and metastasis.   Zhang and Tang (2007) review its discovery and development as a cancer chemopreventive agent.

The preponderance of evidence available from in vitro, animal, and human studies supports the association of sulforaphane with phase II enzyme inductions.  Broccoli sprouts are the richest source of glucoraphanin which is the direct precursor to sulforaphane.  Since broccoli sulforaphane is one of the most potent inducers of phase II enzymes, exploration into broccoli’s impact on other areas of human health, such as cardiovasucular health and upper airway immunity, has been suggested (James et al., 2012).

In Qidong, China, a region where exposures to food-and air-borne carcinogens has been considerable, clinical trials indicate that interventions with well characterized preparations of broccoli sprouts may enhance the detoxication of aflatoxins and air-borne toxins, which may in turn attenuate their associated health risks including cancer in exposed individuals (Kensler et al., 2012).

References

  • James, D., Devaraj, S., Bellur, P., Lakkanna, S., Vicini, J., & Boddupalli, S. (2012). Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli. Nutrition reviews, 70(11), 654-665.
  • Kensler, T. W., Egner, P. A., Agyeman, A. S., Visvanathan, K., Groopman, J. D., Chen, J. G., … & Talalay, P. (2012). Keap1–nrf2 signaling: a target for cancer prevention by sulforaphane. In Natural Products in Cancer Prevention and Therapy(pp. 163-177). Springer, Berlin, Heidelberg.
  • Müller, L., Meyer, M., Bauer, R. N., Zhou, H., Zhang, H., Jones, S., … & Jaspers, I. (2016). Effect of broccoli sprouts and live attenuated influenza virus on peripheral blood natural killer cells: a randomized, double-blind study. PloS one, 11(1), e0147742.
  • Noah, T. L., Zhang, H., Zhou, H., Glista-Baker, E., Müller, L., Bauer, R. N., … & Robinette, C. (2014). Effect of broccoli sprouts on nasal response to live attenuated influenza virus in smokers: a randomized, double-blind study. PloS one, 9(6), e98671.
  • Zhang, Y., & Tang, L. (2007). Discovery and development of sulforaphane as a cancer chemopreventive phytochemical. Acta pharmacologica Sinica, 28(9), 1343-1354.

To Your Health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Transformation to healthy diets by 2050 will require substantial dietary shifts. Global consumption of fruits, vegetables, nuts and legumes will have to double, and consumption of foods such as red meat and sugar will have to be reduced by more than 50%. A diet rich in plant-based foods and with fewer animal source foods confers both improved health and environmental benefits. (Walter Willett MD, Harvard T.H. Chan School of Public Health, 2019)
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Dear Doctor

Why Polyphenols? Because they have molecules that act like generals – organizing and directing the body to repair, heal, protect, and so much more!

In this research article, we will look at how polyphenols improve cardiovascular health.

Lai et al. (2015) reported that total fruit intake (g/day) derived from a 217-item Food Frequency Questionnaire was obtained from 30,458 women (aged 35–69 years) at baseline from 1995–1998., the richest sources of phenolic compounds, correlated with improved cardiovascular health with an estimated 6–7% reduction in deaths from CVDs for every 80 g portion. This study concluded that total fruit intake rather than intake of a specific type of fruit is protective against CVD. In terms of specific types of fruits, commonly researched varieties include berries, such as blackberries, raspberries, black raspberries and blueberries, grapes, citrus fruit, pomegranates, strawberries and apples. These fruits are rich in polyphenols like flavanols, flavonols, anthocyanins, procyanidins, sterols, carotenoids, and hydroycinnamic acids.

Phyto Power- DNA & Cellular Health as a dietary supplement offers several species of especially potent wild-crafted, Alaskan Blueberries, Rosehips, and Dandelions, offering powerful hermetic benefits of polyphenols for DNA and cellular health.

Take two capsules daily.

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The wilds of Alaska provide an amazing environment for powerful plants and berries— fertile volcanic ash soil, and a harsh environment that challenges plants to put out high levels of phenols (e.g. flavonoids) to protect themselves.

To give you an idea on the impact a region has on the concentration of medically useful actives in its produce notice the different between an Alaskan rosehip and the typical European rosehip (the dog-rose) in terms of their phytonutrient load.  All of our fruits and vegetables used in our Therapeutic Food Supplement are sourced with this degree of thoughtfulness for high actives.

Flavonoids

  • Quercetin- 10.50 (Alaskan rosehip) verses 1.05 (European rosehip) in mg/g.
  • Hyperoside- 3.03 verses 4.30
  • Kaempferol- 1.62 verses 0.00
  • Isoquercitin- 0.78 verses 3.51
  • Naringenin- 0.26 verses 0.15
  • Rutin- 0.16 verses 0.67
  • Nothofagrin- 0.26 verses 0.07
  • Luteolin- 0.02 verses 0.01
  • Biochanin A- 0.02 verses 0.00

Catechins

  • Catechin- 72.5 verses 35.70
  • Epicatechin- 67.50 verses 33.70
  • gallocatechin- 0.93 verses 0.86
  • epicatechin gallate- 0.45 verses 0.15
  • catechin gallate- 0.25 verses 0.02.

Organic Acids

  • Ellagic acid- 48.30 verses 5.25
  • Gallic acid- 7.85 verses 0.14
  • p- Coumaric acid- 1.54 verses 0.16
  • Protocatachuic acid- 0.97 verses 0.18
  • Caffeic acid- 0.38 verses 0.00
  • Chlorogenic acid- 0.30 verses 0.05.
  • Salicylic acid- 0.22 verses 0.14
  • Fefulic acid- 0.06 verses 0.09

Vitamins

  • Vitamin C- 25.00 verses 10.00
  • Vitamin B3- 1.09 verses 0.19
  • Vitamin B2- 0.08 verses 0.11
  • Vitamin B1- 0.03 verses 0.01
  • Vitamin B6- 0.01 verses 0.00.

Carotenoids

  • Lycopene- 4.89 verses 2.98
  • b-Carotene- 1.15 verses1.53
  • Lutein- 0.21 verses 0.00
  • Zeaxanthin- 0.17 verses 0.19.

Phyto Power’s Alakan Rosehip provides high amount of catechins.  Two capsules gives one the equivalent of two squares of dark chocolate in catechins without the sugar.

 

References

  • Dower et al. (2015). Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized double-blind, placebo-controlled, crossover trial. Am J Clin Nutr; 101(5): 914-21.
  • Engler at al. (2004). Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. J Am Coll Nutr; 23:197-204.
  • Greenwald SE. (2007). Ageing of the conduit arteries. J Pathol; 211(2): 157-172.
  • Lai, H. T. M., Threapleton, D. E., Day, A. J., Williamson, G., Cade, J. E., & Burley, V. J. (2015). Fruit intake and cardiovascular disease mortality in the UK Women’s Cohort Study. European journal of epidemiology, 30(9), 1035-1048.
  • Lorenz et al. 2007. Addition of milk prevents vascular protective effects of tea. European Heart Journal; 28(2): 2219-2223.
  • Nagao et al. (2007). A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity; 15: 1473-1483.
  • Schroeter et al. (2006). Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. PNAS; 103:1024-1029.
  • Serino, A., & Salazar, G. (2019). Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease. Nutrients,11(1),
  • Tuso et al. (2013) Nutritional Update for Physicians: Plant-Based Diets.
  • WHO (World Health Organization) Cancer Statistics, Sept. (2016).

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Game Changer, produced by James Cameron et al., is a revolutionary new documentary about meat, protein and strength.

It is an absolute must see. You’ll find it on Netflix.

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©2005 – 2020 BioImmersion Inc. All Rights Reserved

Dear Doctor

Cognitive decline is a serious issue. And estimate of 16 million people live with cognitive impairment.  Over 5.1 million Americans live with Alzheimer’s disease (CDC, 2014; 2011). In 2019, Marcum et al.’s survey found that most people are aware of the risks associated with getting dementia but do not know what to do.

James Joseph and Shukitt-Hale have studied blueberries and brain health for many years (e.g., 2010). Their research studies have confirmed that a daily supplementation of blueberries reverse age-related deficits in different groups of aged rats (2019). Both Travica et al. (2019) and Dodd et al. (2019) found blueberry supplementation in adults and children improve cognition performance, and in particular, improve short – and long-term memory.

Wilhelmina Kalt has also led many research teams to study the power of blueberries (e.g., 2013). In a recent article, her team (2019) reviewed current research on the health benefits of blueberries and concluded that it is widely agreed that regular consumption of blueberries can be unconditionally recommended.

Blueberries contain large amounts of phytochemicals, and in particular, blueberries are abundant with anthocyanin pigments, which according to Kalt et al. (2019) makes the greatest impact on brain health.

Our Blueberry Extract is highly concentrated: 80 kilos make 1 kilo of extract – a powerhouse of anthocyanins for brain health. Furthermore, the Blueberry Extract is pure: 100% free of any fillers, excipients or flowing agents.

1-2 capsules twice daily for two weeks to start an intensive program, and 1 capsule a day as a maintenance.

Order Now: Blueberry-Extract

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References:

  • Centers for Disease Control and Prevention. (2017). Cognitive impairment: a call for action now 2011.
  • Dodd, G. F., Williams, C. M., Butler, L. T., & Spencer, J. P. (2019). Acute effects of flavonoid-rich blueberry on cognitive and vascular function in healthy older adults. Nutrition and Healthy Aging, (Preprint), 1-14.Article
  • Kalt, W., Cassidy, A., Howard, L. R., Krikorian, R., Stull, A. J., Tremblay, F., & Zamora-Ros, R. (2019). Recent Research on the Health Benefits of Blueberries and Their Anthocyanins. Advances in Nutrition.Article
  • Kalt, W., Lawand, C., Ryan, D. A., McDonald, J. E., Donner, H., & Forney, C. F. (2003). Oxygen radical absorbing capacity, anthocyanin and phenolic content of highbush blueberries (Vaccinium corymbosum L.) during ripening and storage. Journal of the American Society for Horticultural Science128(6), 917-923. Article
  • Krikorian, R., Shidler, M. D., Nash, T. A., Kalt, W., Vinqvist-Tymchuk, M. R., Shukitt-Hale, B., & Joseph, J. A. (2010). Blueberry supplementation improves memory in older adults. Journal of agricultural and food chemistry58(7), 3996-4000.Article
  • Marcum, Z. A., Hohl, S. D., Gray, S. L., Barthold, D., Crane, P. K., & Larson, E. B. (2019). Brain health and dementia prevention: A mixed-method analysis. American journal of health behavior43(2), 300-310.Abstract
  • Shukitt-Hale, B., Thangthaeng, N., Miller, M. G., Poulose, S. M., Carey, A. N., & Fisher, D. R. (2019). Blueberries Improve Neuroinflammation and Cognition differentially Depending on Individual Cognitive baseline Status. The Journals of Gerontology: Series A74(7), 977-983.Abstract
  • Travica, N., D’Cunha, N. M., Naumovski, N., Kent, K., Mellor, D. D., Firth, J., … & Marx, W. (2019). The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials. Brain, behavior, and immunity.Abstract

Best to you,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Transformation to healthy diets by 2050 will require substantial dietary shifts.  Global consumption of fruits, vegetables, nuts and legumes will have to double, and consumption of foods such as red meat and sugar will have to be reduced by more than 50%. A diet rich in plant-based foods and with fewer animal source foods confers both improved health and environmental benefits.  (Walter Willett MD, Harvard T.H. Chan School of Public Health, 2019)

COVID’s Wake Up Call

April 26, 2020

Dear Doctors

The good news is the wake up call from COVID-19:  We must fundamentally change the way we are relating to and treating Mother Earth.

Last week as we celebrated Earth Day we were reminded of the quote by Chief Seattle:

Whatever befalls the earth, befalls the children of the earth.  If we spit upon the ground we spit upon ourselves… The earth does not belong to us; we belong to the earth.

We have spit on the ground with our air pollution, factory farms, monocultural agriculture, overly indulgent diets,  too much stress and the list goes on. We created a situation where out-of-control virulent pathogens can emerge and meet with our weakened immune systems, resulting in our COVID-19 Pandemic.

The ultimate cure is to clean up our environment and faulty life style habits: use clean energy, practice eco-agriculture, eliminate factory farms, and eat a primarily organic plant based diet.  In the following two photos, the first from India and the second from China we can clearly see that the COVID-19 quarantine has brought about an amazing cleaning of air pollution.

India Pollution copy

China air pollution cleaned

Therapeutic Food Supplements are plant-based and formulated according to scientific research to provide the exact nutrients that powerfully support our immune system and strengthen our health.

References:

  • Mackenzie, J. S., & Smith, D. W. (2020). COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don’t. Microbiology Australia, 41(1), 45-50.
  • Subramaniam, B. (2020). Earth Day Reflections: Hope Amid the Pandemic. ACS Sustainable Chemistry & Engineering, 8(15), 5817.

Best to you,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Environmental Working Group (EWG) mission is to empower people to live healthier lives in a healthier environment.  With breakthrough research and education, we drive consumer choice and civic action.

Dear Doctor

The Covid-19 (Coronavirus) enters the respiratory track primarily through the nose. (Dr. Martin S. Hirsch, senior physician, Infectious Diseases, Mass General Hospital).

Once inside the body, it begins its journey of destruction, first infecting the nasal sinus on its way to the respiratory tree. Covid-19 moves fast into the air sacs of the lungs causing pneumonia for the affected person, unless it is stopped by the host’s immune system.  Younger patients have a more vigorous immune response compared to older patients.  No matter how healthy and active you are, your risk for getting pneumonia increases with age, although we are learning that younger people can suffer as much as older people.

Bottom line, we need a balanced and competent immune system response no matter how old or young we are.  A capable immune system quickly identifies and kills this viral intruder. As important, the immune system also needs to effectively manage its inflammatory response, so that it doesn’t overwhelm the lungs with collateral damage from using too much of its inflammatory weaponry. Balancing our immune response is key in the healing process of this flu.

How do we balance the immune system so it is healthy and appropriately responds to any viral invaders?

First, we need to pay attention to building a healthy mucous barrier against pathogens.  70% of our immune system resides around the outer walls of our intestines in the gastro-intestinal lymphoid tissues (GALT). The mucous membrane of our sinuses, lungs, and gastrointestinal tract are all connected to the blood system which carries immune system cells (e.g., natural killer cells, lymphocytes etc).

Probiotic organisms convert undigested soluble fibers (e.g., inulin, beta glucan, and pectin) into short chain fatty acids like butyric acid to energize the colon’s lining to healthily regenerate its cells and tighten up the junction (space) between the cells with the membrane. That is one of our goals – achieving a smooth and healthy mucosal barrier.

When these junctions are too wide, the loose space between the cells allows particles to get through and cause a chronic immune response. And as we know, immune response of any kind causes inflammation, and a chronic ongoing reaction weakens the immune system.

Second, Probiotic organisms love plant polyphenols and break their molecular chains so the phenolic molecules can be absorbed into the systemic circulation and turn on the repair and regenerative power of our cells. That is our second goal – to turn on the repair mechanism in our bodies, lower inflammation, and bring our system into balance (homeostasis).

For a measured combination of polyphenols and probiotics we suggest the High ORAC Synbiotic

HO F

And the No. 7 Systemic Booster

No.7 FTo add weaponry that is known as the Russian Penicillin due to its anti-microbial abilities, we suggest:   Garlic as a foundational supplements to support the immune system.

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If you are prone to respiratory conditions add the Fructo Borate Complex.

FB FReferences

  • Abbas, H. M. K., Kong, X., Wu, J., Ali, M., & Dong, W. (2019). Antimicrobial Potential of Genes from Garlic (Allium sativum L.). In Studies on Garlic. IntechOpen
  • Biagi, E., Candela, M., Turroni, S., Garagnani, P., Franceschi, C., & Brigidi, P. (2013). Ageing and gut microbes: perspectives for health maintenance and longevity. Pharmacological Research, 69(1), 11-20.
  • Boor, P. P., De Ruiter, P. E., Asmawidjaja, P. S., Lubberts, E., van der Laan, L. J., & Kwekkeboom, J. (2017). JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa. Translational Research, 188, 67-79.
  • Catarino, M. D., Silva, A., & Cardoso, S. M. (2017). Fucaceae: A source of bioactive phlorotannins. International journal of molecular sciences, 18(6), 1327.
  • Ding, S., Jiang, H., & Fang, J. (2018). Regulation of Immune Function by Polyphenols. Journal of immunology research, 2018. https://doi.org/10.1155/2018/1264074
  • Hunter, J. M., Nemzer, B. V., Rangavajla, N., Biţă, A., Rogoveanu, O. C., Neamţu, J., … & Mogoşanu, G. D. (2019). The Fructoborates: Part of a Family of Naturally Occurring Sugar–Borate Complexes—Biochemistry, Physiology, and Impact on Human Health: a Review. Biological trace element research, 188(1), 11-25.
  • Lamarche, B., Paradis, M. È., & Couture, P. (2010). Study of the acute impact of polyphenols from brown seaweeds on glucose control in healthy men and women. The FASEB Journal, 24(1 Supplement), 209-4.
  • Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S., & Manson, J. J. (2020). COVID-19: consider cytokine storm syndromes and immunosuppression. The Lancet.
  • Ritchie, A. I., & Singanayagam, A. (2020). Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?. The Lancet.
  • Salehi, B., Zucca, P., Orhan, I. E., Azzini, E., Adetunji, C. O., Mohammed, S. A., … & Armstrong, L. (2019). Allicin and health: A comprehensive review. Trends in Food Science & Technology.
  • Singanayagam, A., Glanville, N., Girkin, J. L., Ching, Y. M., Marcellini, A., Porter, J. D., … & Zhu, J. (2018). Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations. Nature communications, 9(1), 1-16.
  • Takemura, M., Matsumoto, H., Niimi, A., Ueda, T., Matsuoka, H., Yamaguchi, M., … & Nakamura, T. (2006). High sensitivity C-reactive protein in asthma.European Respiratory Journal, 27(5), 908-91
  • Thomas, B. J., Porritt, R. A., Hertzog, P. J., Bardin, P. G., & Tate, M. D. (2014). Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon. Scientific reports, 4(1), 1-11.
  • Wilson, E. A., & Demmig-Adams, B. (2007). Antioxidant, anti-inflammatory, and antimicrobial properties of garlic and onions. Nutrition & food science, 37(3), 178-183.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

30 Days of Reconnection began Monday, and it is not too late for you to join in. Biomimicry has the answer to our existential dilemma, it lies in reconnecting with the natural world that surrounds us. For the next 28 days culminating on the Earth Day Celebration we will be guided in how we, the biosphere, can become whole and healthy.

 

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©2005 – 2019 BioImmersion Inc. All Rights Reserved