Dear Friends

Senescence is the technical word for aging. It is the condition or process of deterioration with age- a loss of a cell’s power of division and growth. The question is, What does healthy ageing look like?

We certainly can see unhealthy ageing all around us- people ridden with chronic degenerative diseases.  Ageing is among the greatest known risk factors for most human diseases: of the roughly 150,000 people who die each day across the globe, about two thirds die from age-related causes (Dillin et al., 2014).

blueberry X 4So, what methods can be used today to support healthy ageing?  An ageing where our bodies may be slowing down but where our bodily systems are still functioning well.  How for example can we keep our brain sharp, even to the very end of our life?

Research suggests that the polyphenolic compounds found in fruits, such as blueberries, may exert protection against Alzheimer’s or Parkinson’s diseases; that they do indeed provide benefits for cognitive health, protection, and restoration (Joseph et al., 2007).

Spencer’s (2010) research, Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain, explores the potential inhibitory or stimulatory actions of flavonoids within three sytems:  The first, through their interactions with important neuronal and glial signaling cascades in the brain; second, through an ability to improve peripheral and cerebral blood flow and trigger angiogenesis and neurogenensis in the hippocampus; third, by their capacity to directly react with and scavenge neurotoxic species and pro-inflammatory agents produced in the brain as a result of both normal and abnormal brain senenscence.

Blueberry Extract is the most powerful blueberry extract on the market, our 100% North American blueberry (Vaccinium corymbosum) provides a comprehensive profile of anthocyanins.  Scientists describe blueberries as agents of neuro-regeneration. Research studies show that blueberry and blueberry extract offer a potent and effective brain food to support cognition, memory, and the general health of our nervous system.

  • Blueberry Extract- 1 capsule daily

Phyto Power Photo 10Phyto Power is formulated to support DNA and cellular integrity. A wildcrafted wonder from remote, pure, and fertile regions of Alaska, Phyto Power is filled with biologically high actives, creating a phenolic powerhouse. Blueberries, rose hip, and dandelion are shown in research to help maintain cellular integrity, suppressing or interfering with oncogenic transformation, bolstering antioxidant and anti-inflammatory defenses, and contributing significant re-generative health benefits.

  • Phyto Power- 2 capsules daily

References:

  • Dillin, A., Gottschling, D. E., & Nyström, T. (2014). The good and the bad of being connected: the integrons of aging. Current opinion in cell biology, 26, 107-112.
  • Joseph, J.A., Shukitt-Hale, B., & Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence . Ann NY Acd Sci, 1100, 470-85. DOI: 10.1196/annals.1395.052
  • Spencer, J. P. (2010). Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain. Proceedings of the Nutrition Society, 69(2), 244-260 https://doi.org/10.1017/S0029665110000054

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Globe_Home 3

The Food Revolution Summit 2018(April 26 to May 6) is over but you can still tap into the wonderful information and all the great presenters.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

Cognitive decline, including Alzheimer’s, dementia, and other neurological diseases are linked with old age, yet we see these brain/nerve issues in both young and old.

There is a large body of scientific evidence regarding blueberry and blueberry extract’s benefits for cognitive health, protection, and restoration. See Food Science and References below and visit Blueberry Extract and Phyto Power research tab on the product page.

blueberry X 4
Blueberry Extract is the most powerful blueberry extract on the market, our 100% North American blueberry (Vaccinium corymbosum) provides a comprehensive profile of anthocyanins.  Scientists describe blueberries as agents of neuro-regeneration. Research studies show that blueberry and blueberry extract offer a potent and effective brain food to support cognition, memory, and the general health of our nervous system.

  • Blueberry Extract- 1 capsule daily

Phyto Power Photo 10Phyto Power is formulated to support DNA and cellular integrity. A wildcrafted wonder from remote, pure, and fertile regions of Alaska, Phyto Power is filled with biologically high actives, creating a phenolic powerhouse. Blueberries, rose hip, and dandelion are shown in research to help maintain cellular integrity, suppressing or interfering with oncogenic transformation, bolstering antioxidant and anti-inflammatory defenses, and contributing significant re-generative health benefits.

  • Phyto Power- 2 capsules daily

Food Science:

Esteemed research scientists demonstrate that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills  (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).

References:

  • Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641.
  • Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. (2007). Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol Aging, 28, 1187-1194. DOI: 10.1016/j.neurobiolaging.2006.05.031
  • Carey, A.N., Gomes, S.M., & Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet.J Agric Food Chem, 62, 3972-3978. DOI: 10.1021/jf404565s
  • Malin, D.H., Lee, D.R., Goyarzum P., Chang, Y.H., Ennis, L.J., Beckett, E., Shukitt-Hale, B., Joseph, J.A. (2011). Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats.Nutrition, 27, 338-342. DOI: 10.1016/j.nut.2010.05.001  
  • Brewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., & Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, 21, 991-998. DOI: 10.1016/j.jnutbio.2009.08.005
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:10.1080/1028415031000111282
  • Joseph, J.A., Shukitt-Hale, B., & Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence . Ann NY Acd Sci, 1100, 470-85. DOI: 10.1196/annals.1395.052
  • Miller, M.G., Shukitt-Hale, B. (2012). Berry fruit enhances beneficial signaling in the brain. J. Agric. Food Chem,60(23), 5709–5715. DOI: 10.1021/jf2036033
  • Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., & Bickford, P.C. (1999). Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci, 19(18), 8114-21. . Article
  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci.29(41), 12795–12801. DOI:10.1523/JNEUROSCI.3520-09.2009
  • Shukitt-Hale, B., Bielinski, D. F., Lau, F. C., Willis, L. M., Carey, A. N., & Joseph, J. A. (2015). The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. British Journal of Nutrition, 114(10), 1542-154.
  • Shukitt-Hale, B. (2012). Blueberries and neuronal aging. Gerontology, 58, 518-523. DOI: 10.1159/000341101DOI:10.1021/jf072505f

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Food Revolution Summit 2018(April 26 to May 6) is over but you can still tap into the wonderful information and all the great presenters.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends
Original Photo
Who proclaimed first that “All disease begins in the gut”? The first three that will answer correctly, or close enough, will receive the Original Synbiotic formula!

In this day and age medical science with its focus on the human GI tract microbiome and a whole food plant-based diet seems to be calling forth similar sentiments.

Dr. Francis Collins, director of NIH, in a talk entitled Supercharging Science for the Superorganism, said that we are a chimera-like creature, governed by our 10 trillion human cells and their 22,000 genes and the microbiome community in the GI tract — all 100 trillion of them with their 2 to 8 million genes (2015).

Possemier et al. (2010) has said it well when his team suggested we  consider the complex microbial ecosystem in our intestines as a separate organ within the body.

Martinez et al (2017) weighed in on this with their research paper entitled- Western diets, gut dysbiosis, and metabolic diseases: Are they linked? And indeed dysbiosis from Western diets is believed to be one of the reason obesity afflicts 36.5% of the US population and 600 million individuals world-wide.

The World Health Organization (WHO), Harvard Medical School, Kaiser Permantente, just to name a few, are all calling for a change of our dietary habits to one that focuses on a whole food plant based diet. Did you also know that probiotics love plants’ fiber and polyphenols? Plants are their most important source of food, and plants are also our most important source of foods.

See below in Green Facts the teaser on the new documentary by Cameron, The Game Changers.

At BioImmersions, we focus on probiotics,  plant polyphenols, fiber, and phytonutrients of eco-farmed or wildcrated whole foods. Our supplements are powerfully concentrated. We all recognize that it is difficult to change a diet that we are addicted to.  Here are two of our products that can make a big difference in the health of your gut microbiome, which translates to health in the whole body.

Phyto Power– 1 capsule daily
Phyto Power Photo 6

  • Three species of Rosehip, wildcrafted, whole fruit and seeds (100% w/w), refractory dried, three Rosa species, 200mg per capsule.
  • Four species of Dandelion, wildcrafted, aerial parts (90% w/w), root (10% w/w) with flower, refractory dried, four Taraxacum species, 200mg per capsule.
  • Four species of Blueberry, wildcrafted, fruit (>90% w/w), leaves and stem (<5% w/w), refractory dried, four Vaccinium species, 100mg per capsule.

 

 

Original Synbiotic: 1 tsp. dailyOriginal Photo 4

20 billion cfu/tsp of certified strains of pedigreed probiotic with Therapeutic Foods in a synbiotic formula of L. acidophilus, B. longum, L. rhamnosus, L. plantarum, S. thermophilus and 4 grams of inulin derived from organic chicory fiber. Advanced freeze-drying technology. 120 grams/bottle. 4 grams/ tsp. Dairy free.  Soy free. Gluten free. No excipients.


References


Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Game Changers- a teaser for this documentary by James Cameron
(http://gamechangersmovie.com/)

“What I discovered was so revolutionary, with such profound implications for performance, health, and the future of the planet itself, that I had to share it with the world.”  Quote from James Wilks

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved
Dear Friends

Did you know that polyphenols from berries and plants are the most favored foods for the probiotics genera Lactobacillus and Bifidobacterium in the gut?

The berries and plants enhance the growth of Lactobacillus and Bifidobacterium inside the gut microbiome, while inhibiting many pathogenic organsims.

For example, Possemiers et al.’s (2011)  “The intestinal microbioime: a separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals,” explains that rich polyphenolic molecules from berries and plants are broken down by probiotic organisms into many important sub-molecules that are more bioavailable yet still contain their classic polyphenolic structure to serve the body as antioxidants, anti-inflammatories, antimicrobials, anti cancer, anti diabetes and more  … no wonder berries and plants are the preferred prebiotics foods for the Lactobacillus and Bifidobacteria!

 

Phyto Power– 1 capsule daily
Phyto Power Photo 6

  • Three species of Rosehip, wildcrafted, whole fruit and seeds (100% w/w), refractory dried, three Rosa species, 200mg per capsule.
  • Four species of Dandelion, wildcrafted, aerial parts (90% w/w), root (10% w/w) with flower, refractory dried, four Taraxacum species, 200mg per capsule.
  • Four species of Blueberry, wildcrafted, fruit (>90% w/w), leaves and stem (<5% w/w), refractory dried, four Vaccinium species, 100mg per capsule.

 

 

Original Synbiotic: 1 tsp. dailyOriginal Photo 4

Contains:  20 billion cfu/tsp of certified strains of pedigreed probiotics (L. acidophilus,  B. longum, L. rhamnosus, L. plantarum and S. thermophilus) and 3.5 grams of inulin derived from organic chicory fiber.  Advanced freeze-drying technology.

120 grams/bottle. 4 grams/ tsp.  Dairy free.  Soy free. Gluten free. No excipients.

References

 

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor

Green Facts:

Globe_Home 3Phyto Power is indeed powerful. In fact, Dinstel et al. (2013) found the antioxidant levels of Alaska’s wild berries to be extremely high, ranging from 3 to 5 times higher in ORAC values than cultivated berries from 48 other states. For example, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. When the berries were dehydrated, per gram the ORAC values increased.*
 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Autism and Clostridia

February 24, 2018

Dear Friends

Research ascribes various etiologies to Autism Spectrum Disorder (ASD).  There are exogenous factors such as iatrogenic drugs, pollutants of various kinds, and over use of antibiotics; and there are the endogenous factors such as dysbiosis of the GI Tract, mitochondrial dysfunction, and of course genetics. Interestingly, genetic causation is found to be in the low percentile, whereas dybiosis and mitochondrial dysfunction conditions present major links to ASD.

Let’s focus on dysbiosis.  Overgrowth of clostridia, bacteriodes, and desulfovibrio are all ASD-associated bacterial populations. The overuse of antibiotics enables the clostridial family of bacteria to dominate because their spore forming ability resist many antibiotics and they can easily gain a foothold over good bacteria.

Clostridia is a big producer of the SCFA propionate. Too much propionate in the systemic circulation (which is able to cross the blood-brain barrier) becomes neurological and mitochondrial toxins, disrupting and causing the very symptoms that we see with autistic patients.

There is strong support in the literature for foundational probiotic organisms that reduce the overload of clostridium. These are the organisms we have chosen for our probiotics.

Research is showing that L. plantarum, L. casei rhamnosus, B. longum and even L. acidophilus can put out bacterocins against clostridia.  Doctors who have used our Original Synbiotic and our Supernatant Synbiotic (either one works) found improvement in the behaviors of ASD patients.

I would recommend adding Phyto Power for the high potency of polyphenolics grown in remote Alaskan regions. Phenols are shown in research as antimicrobials, inhibiting many pathogenic organisms including those implicated in ASD, yet at the same time, they enhance both the growth of the Bifido and Lactobacillus genera.

I suggest the following dosage:

Original Synbiotic: up to 1 tsp. daily. With very young patients start with an eight of a tsp and work up slowly adjusting the dosage. Back off just a little from a dosage that causes reaction. You be able to get up to a tsp dose in about a month of gradually ratcheting it up.

As a reminder this product contains L. plantarum, L. casei rhamnosus, L. acidophilus, B. longum and S. thermophiles plus organic chicory root inulin which is very bifido and lacto genic.  Each of the organism are good butyrate produces, and as we know, butyrate helps to heal a leaky gut which is a big problem for ASD patients.

Phyto Power– 1 capsule daily (if they can’t take capsules then just open up the capsule and take the powder directly).

References

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Phyto Power is indeed powerful. In fact, Dinstel et al. (2013) found the antioxidant levels of Alaska’s wild berries to be extremely high, ranging from 3 to 5 times higher in ORAC values than cultivated berries from 48 other states. For example, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. When the berries were dehydrated, per gram the ORAC values increased.*
 

©2005 – 2018 BioImmersion Inc. All Rights Reserved