No. 7 Systemic Booster

Dear Friends

No. 7 brings together the power of the polyphenols with pedigreeds strains of probiotics.
No. 7 Systemic Booster 13
A reduced life span is an outcome associated with many prevalent diseases, including diabetes, obesity, and high blood pressure. In seeking to prevent these diseases, many researchers have looked into potential therapeutic benefits of naturally occurring compounds.

AMP-activated protein kinase (AMPK) is a major metabolic-sensing protein implicated in the prevention of metabolic disorders, or in minimizing the effects thereof, via the regulation of both upstream and downstream target molecules.

In the field of food and nutrition, the current focus lies in the finding of components that activate AMPK. AMPK is a serine/threonine protein kinase and is activated by several natural compounds, including resveratrol, epigallocatechin gallate, berberine, and quercetin. AMPK activation can induce ATP (adenosine triphosphate) generation through pathways such as glycolysis and β-oxidation. By contrast, ATP-consuming pathways, including fatty acid and cholesterol syntheses, and gluconeogenesis, are suppressed by AMPK activation.

The No. 7 Systemic Booster suggestion daily dose:  1 tsp.

Food Science

We used to think of the colon as a storage place for fecal matter, on its way out, whose function was to reabsorb water and minerals.  Now, thru the worldwide research on the human microbiome, we understand that the colon is home to another digestive organ in our body- the GI Microbiome, whose metabolic capacity is 100 fold that of our liver.

A healthy gut microbiome residing in the colon is “the organ” in our body that consumes the fibers (inulins, pectins, beta glucans, resistant starches) and polyphenols in our diet as food, breaking down the longer phenolic chains into shorter ones that are more bioavailable, enabling these phytochemicals to enter into our body and hometically supply their multitude of benefits towards the health of all bodily systems.

Therefore, seeding the digestive system with proven probiotic organisms and bringing in a healthy mix of plants, berries and fruits into your diet is an absolute must for health now and for health long in one’s old age.


Sincerely yours,


We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.


Green Facts:

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The Game Changers- a teaser for this documentary by James Cameron

“What I discovered was so revolutionary, with such profound implications for performance, health, and the future of the planet itself, that I had to share it with the world.” Quote from James Wilks


©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

A leaky gut leads to chronic inflammation within our body (liu, li, & Neu, 2005).  And, chronic inflammation is causative for a whole host of non-communicable diseases—autoimmune disease, metabolic syndrome, obesity, diabetes, CVD, cancer, neurological disease and more (Goldsmith, 2014).

What factors lead to the prevention or treatment of Leaky Gut Syndrome?

Our diets greatly influence the make up of our GI tract microbiome.  Research data show that eating the right foods to supply plenty fiber and polyphenols on a regular basis creates a healthy balance of human friendly bacteria within our gastrointestinal system, leading to the tighteninng of the intestinal cellular junctions and the elimination of a leaky gut (Claussen, 2012).

To aid in the consistent intake of fiber, probiotics, and polyphenols:

Food Science

Health-promoting effects of the microflora may include immunostimulation, improved digestion and absorption, vitamin synthesis, inhibition of the growth of potential pathogens and lowering of gas distension.  Detrimental effects are carcinogen production, intestinal putrefaction, toxin production, diarrhoea/constipation and intestinal infections (Saulnier, 2009).

Stool microbiota of individuals with different types of habitual diets (e.g., vegetarians or vegans versus omnivores or from geopraphically distinct areas) have been charactertized.  It has become evident that the diet has a dominatn role on the stool microbiota and that the diet-driven changes in it occur with days to weeks (Simoes, 2013).

The data indicate that the frailest older people tend to harbour similar intestinal microbial communities.  The study also suggests that this shift in their gut microbiome is driven by a diet high in fat and lacking in fibre, and that a decline in our microbial community underlies ill health as we grow old (Wu, 2011; Claussen, 2012; Simoes, 2013.).


  • Claesson MJ, Jeffery IB, Conde S, Power SE, O’Conner EM, Cusack S, Harris HM … et al. (2012). Gut microbiota composition correlates with diet and health in the elderly. Nature; 9,488(7410). 178-84.
  • Goldsmith Jr, Sartor RB. (2014). The role of diet on intestinal microbiota metabolism: downstream impacts on host immune function and health, and therapeutic implications. J Gastroenterol, 49(5): 785-98.
  • Liu, Z., Li, N., & Neu, J. (2005). Tight junctions, leaky intestines, and pediatric diseases. Acta Paediatr, 94(4), 386-93.
  • Maukonen J, Saarela M. (2015). Human Gut microbiota:  Does diet matter? Proc Nutr Soc; 74(1): 23-36.
  • Saulnier MD, Kolida S, Gibson GR. (2009). Microbiology of the human intestinal tract and approaches for its dietary modulation. Curr Pharm Des; 15(13): 1403-14.
  • Simoes CD, Maukonen J, Kaprio J, Rissanen A, Poetiainen KH, Saarela M. (2013). Habitual dietary intake is associated with stool microbiota composition in monzygotic twins. J Nutr; 143(4): 417-23.
  • Tuohy KM, Gougolias C, Shen Q, Fava F, Ramnani P. (2009). Studying the human gut microbiota in the trans-omics era–focus on metagenomics and metabonomics. Curr Pham Des 15(13): 1415-27.
  • Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA … et al. (2011).  Linking long-term dietary patterns with gut microbial enterotypes. Science; 334(6052): 105-8.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3David Granet MD and Rob Knight PhD converse regarding the Microbiome. Some points by Knight:  Avoid fries and certain carbohydrates; but not all for fibers both soluble and insoluble are very important for microbiome health.  Also eat a rainbow of colored vegetables and fermented foods.

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends

Well, in just 12 days from today it’s the Hawaii Doc Talks Convention!, but who’s counting.

On Friday March 3rd we will host the breakfast in Maui and teach on a topic that gets right to the heart of the matter regarding food as medicine:  The Intelligence and Power of Therapeutic Food Supplements: Science, Research, and Protocol.

Click on the above link to the see our learning objectives for the doctors.  The third objective is: Discover the next generation probiotics — infection fighting Supernatant metabolites and immune boosting microRNA.

Remember, if you can’t join us this time around, I would be more than happy to meet you via the zoom meeting format online.  Just let me know and we’ll set it up.

The two photos below present our synbiotic formulas.  The top one highlighting our new LactORN Synbiotic and the photo below seven more probiotic offerings.


Understanding our microbiome is without a question one of the hottest topics in medicine. Hippocrates, 2400 years ago, said that all disease begins in the gut.  In a recent speech Dr. Francis Collins, past director of the Human Microbiome Project, and present director of the NIH said,

We are a chimera-like creatire whose healthy metabolic and physiologic functioning is governed by not only our 10 trillion human cells and their 22,000 genes but also by our human microbiome community that co-habitate our bodies, all 100 trillion of them with their 2 to 8 million genes—most of them bacteria living in our GI tract. (2015, Supercharging Science for the Superorganism)


“An ever-growing number of studies have demonstrated that changes in the composition of our microbiomes correlate with numerous disease states, raising the possibility that manipulation of these communities could be used to treat disease.”  (HMP Home page).

The microbiome must be taken into account regarding metabolic diseases (Metabolic Syndrome, Obesity, Diabetes, Heart Disease), gastrointestinal disease (IBS, IBD), and neuroligical health.

Yours truly,

Seann Bardell CEO
BioImmersion Inc.

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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  • Dr. Francis Collins, the Director of the NIH recently said “The time of the importance of the microbiome and human health has arrived.  Our gut microbiome is of central importance for our immune system health, our neural-transmitter health, our GI tract health, and our metabolic health.

Tired of Your Colds & Flu?

January 23, 2017

Dear Friends

We are in the midst of the season for colds and flu, and added stress certainly does not help the situation, or does it?

Suzanne Segerstrom and Gregory Miller (2004), Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry, examined more than 300 empirical articles describing a relationship between psychological stress and parameters of the immune system in human participants.

Segerstrom and Miller found that acute stressors (lasting minutes) were associated with potentially adaptive up-regulation of some parameters of natural immunity and down-regulation of some functions of specific immunity.  But chronic stressors on the other hand were associated with suppression of both cellular and humoral measures (see also Priyandarshini & Aich, 2012).

Chronic stress compromises our immune system putting us at risk to bacterial and viral infections; where as an acute momentary stressor can enhance/prime the innate immune system to more apply protect us from invading bacteria and viruses.  The trick is knowing how to prime our immune system successfully.

Do you have a tough time getting rid of your sore throat, cold, or flu?  Three BioImmersion products support the more robust functioning of our immune system to nip a cold. The garlic and No7 are famous for kicking out nasty sore throats and colds, while the LactORN alerts our immune system into action.

Recipe for Immune System support against colds and flu

  • LactORN- 1tsp. daily (held into the mouth until it dissolves). This paradigm shifter product kicks the fast acting (innate) immune system into gear!
  • No. 7 Systemic Booster- 1 tsp. daily (mix in a glass of water).
  • Organic Garlic- 1-2 capsules. For sore throats, open the capsules into a cup of water (or your mix with No7) and stir, let sit for one minutes and drink.

Both the LactORN and the No.7 Systemic Booster contain ingredients that challenge our immune system—namely, the oligoribonucleotides (ORNs) and the supernatant broth (whole dead-cells of probiotics, vitamins & minerals, enzymes, bacteriocin, ORNs, and more), respectively.  No.7 and LactORN also contain strong probiotic organisms that actually fight against pathogens. Garlic, especially when it is sourced with high allicin potential and manufactured correctly to preserve its high actives is known to offer a wonderful broad spectrum antimicrobial.  Hard on many pathogens but minimally so on good lactic acid bacteria in our probiotic mix, garlic is a perfect agent against colds and flu.

Food Science

Segerstrom and Miller (2004) divided stressors into 6 categories: Acute time-limited, Brief naturalistic, Event sequence, Chronic, Distant, and Life event.  Each type has a different effect on our immune system ability to defend us from colds and flus.

The Acute time-limited stressor category falls within the fight-or flight responses, an encounter more common to our ancestors.  Fighting and/or fleeing carries the risk of injury and subsequent entry of infectious agents into the bloodstream or skin.  Any wound in the skin is likely to contain pathogens that could multiply and cause infections (Williams & Leaper, 1998).  Stress-induced changes in the immune system that could accelerate wound repair and help prevent infections from taking hold would therefore be adaptive and selected along with other physiological changes that increased evolutionary fitness.

Cells involved in natural immunity do not provide defense against any particular pathogen; rather, they are all-purpose cells that can attack a number of different pathogens and do so in a relatively short time frame (minutes to hours) when challenged.


  • Priyandarshini S, Aich P. (2012). Effects of Psychological Stress on Innate Immunity and Metabolism in humans:  A Systematic Analysis.
  • Segerstrom SC, Miller GE. (2004). Psychological Stress and the Human Immune System:  A Meta-Analytic study of 30 Years of inquiry. Psychol Bull; 130(3): 601-630.
  • Williams, N. A., & Leaper, D. J. (1998). Infection. In D. J. Leaper & K. G. Harding (Eds.), Wounds: Biology and management (pp. 71– 87). New York: Oxford University Press.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
Green Facts:

Globe_Home 3How can we deliver nutrition in a way that nourishes both planet and people?  See Janine Benyus, Dec 1, 2016 key note talk, Biomimicry as a Cooperative Inquiry, on nature-inspired breakthroughs in agriculture.

Dear Friends

Emerging science supports therapeutic roles for berries to prevent and reduce metabolic syndrome. (See Protocols for Health in our new website)

Add any of our berry collection of supplements to decrease risk markers – to every meal that contains sugars of any kind, fat (from dairy, meat, or eggs; and even plant oils), and grains.

Metabolic syndrome is a pre-diabetic state characterized by several cardiovascular risk factors:  abdominal obesity, atherogenic dyslipidemia, raised blood pressure, insulin resistance, pro-inflammatory state and prothrombotic state.

Basu and Lyons in their 2012 research (Strawberries, blueberries, and cranberries in metabolic syndrome: clinical perspectives) stated that,

Interventional studies reported by our group and others have demonstrated the following effects: strawberries lowering total and LDL-cholesterol, but not triglycerides, and decreasing surrogate biomarkers of atherosclerosis (malondialdehyde and adhesion molecules); blueberries lowering systolic and diastolic blood pressure and lipid oxidation and improving insulin resistance; and low-calorie cranberry juice selectively decreasing biomarkers of lipid oxidation (oxidized LDL) and inflammation (adhesion molecules) in metabolic syndrome.

Mechanistic studies further explain these observations as up-regulation of endothelial nitric oxide synthase activity, reduction in renal oxidative damage, and inhibition of the activity of carbohydrate digestive enzymes or angiotensin-converting enzyme by these berries.

(See Food Science and Green Facts below for more on this important discussion).

Therapeutic Food protocol for support in reducing risk of Metabolic Syndrome

Food Science

Phyto Power supplies the phytonutrient power of multi-species of wild-crafted Alaskan blue berries and rosehips, and four species of dandelions picked in the wild.  This product is loaded with bioflavonoids (Dinstel, 2013).  Consuming 2 capsules of the Phyto Power is equivalent to eating 6 wild-crafted Alaskan rosehips (seeds and all), a small hand full (covering the palm of your hand) of wild-crafted blueberries, and one small cup of dandelion salad (from the wild meadows of Alaska) complete with flowers and roots.

No. 7 Systemic Booster not only supports you with powerful Bulgarian strains of probiotic bacteria, supernatant, and strategically selected nutriceuticals, but also provide the glycemic lowering power of whole organic cranberry, pomegranate, tart cherry and pineapple, all with high actives.

Food Science:

Throne et al. (2012) demonstrated the blunting effect on the insulin spike with high glycemic foods when you add whole berries.  They showed graphically what white bread does to our insulin levels within 2 hours after eating it.  Adding black currents and lingenberries when eating the same amount of white bread and there’s less of an insulin spike, even though by eating the berries you’ve added additional sugar (fructose) to the meal.  How do we account for this?

The soluble fibers in the berries has a gelling effect in our intestines that slows the release of sugars.  As viscosity increases, the glycemic load goes down.  Additionally, fruit phytonutrients inhibit the transportation of sugars through the intestinal wall into our blood stream (Madero, 2011).


  • Basu A. Lyons TJ. (2012). Strawberries, blueberries, and cranberries in the metabolic syndrome: clinical perspectives. J Agric Food Chem; 60: 5687-92.
  • Dinstel R.R., Cascio J., & Koukel S. (2013). The antioxidant level of Alaska’s wild berries: high, higher and highest. Int J Circumpolar Health;72 doi:10.3402/ijch.v7210.21188.
  • Lustig, RH. (2013).  Fructose: It’s “Alcohol Without the Buzz”.  Adv Nutr; 4: 226-235.
  • Madero et al. (2011). The effect of two energy-restricted diets, a low-fructose diet versus a moderate natural fructose diet, on weight loss and metabolic syndrome parameters: a randomized controlled trial.  Metabolism, Clinical and Experimental; 60: 1551-1559.
  • Petta et al. (2013). Industrial, not fruit fructose intake is associated with the severity of liver fibrosis in genotype 1 chronic hepatitis C patients. Journal of Hepatology; 59: 1169-1176.
  • Throne et al. (2012). Postprandial glucose, insulin, and free fatty acid responses to sucrose consumed with blackcurrants and lingonberries in healthy women. Am J Clin Nutr; 96: 527-33.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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  • If the fructose in sugar and high fructose corn syrup has been considered alcohol without the buzz in terms of the potential to inflict liver damage, what about the source of natural fructose, fruit?  See Dr. Michael Greger’s informative Video:   If Fructose is Bad, What About Fruit?