Tired of Your Colds & Flu?

January 23, 2017

Dear Friends

We are in the midst of the season for colds and flu, and added stress certainly does not help the situation, or does it?

Suzanne Segerstrom and Gregory Miller (2004), Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry, examined more than 300 empirical articles describing a relationship between psychological stress and parameters of the immune system in human participants.

Segerstrom and Miller found that acute stressors (lasting minutes) were associated with potentially adaptive up-regulation of some parameters of natural immunity and down-regulation of some functions of specific immunity.  But chronic stressors on the other hand were associated with suppression of both cellular and humoral measures (see also Priyandarshini & Aich, 2012).

Chronic stress compromises our immune system putting us at risk to bacterial and viral infections; where as an acute momentary stressor can enhance/prime the innate immune system to more apply protect us from invading bacteria and viruses.  The trick is knowing how to prime our immune system successfully.

Do you have a tough time getting rid of your sore throat, cold, or flu?  Three BioImmersion products support the more robust functioning of our immune system to nip a cold. The garlic and No7 are famous for kicking out nasty sore throats and colds, while the LactORN alerts our immune system into action.

Recipe for Immune System support against colds and flu

  • LactORN- 1tsp. daily (held into the mouth until it dissolves). This paradigm shifter product kicks the fast acting (innate) immune system into gear!
  • No. 7 Systemic Booster- 1 tsp. daily (mix in a glass of water).
  • Organic Garlic- 1-2 capsules. For sore throats, open the capsules into a cup of water (or your mix with No7) and stir, let sit for one minutes and drink.

Both the LactORN and the No.7 Systemic Booster contain ingredients that challenge our immune system—namely, the oligoribonucleotides (ORNs) and the supernatant broth (whole dead-cells of probiotics, vitamins & minerals, enzymes, bacteriocin, ORNs, and more), respectively.  No.7 and LactORN also contain strong probiotic organisms that actually fight against pathogens. Garlic, especially when it is sourced with high allicin potential and manufactured correctly to preserve its high actives is known to offer a wonderful broad spectrum antimicrobial.  Hard on many pathogens but minimally so on good lactic acid bacteria in our probiotic mix, garlic is a perfect agent against colds and flu.

Food Science

Segerstrom and Miller (2004) divided stressors into 6 categories: Acute time-limited, Brief naturalistic, Event sequence, Chronic, Distant, and Life event.  Each type has a different effect on our immune system ability to defend us from colds and flus.

The Acute time-limited stressor category falls within the fight-or flight responses, an encounter more common to our ancestors.  Fighting and/or fleeing carries the risk of injury and subsequent entry of infectious agents into the bloodstream or skin.  Any wound in the skin is likely to contain pathogens that could multiply and cause infections (Williams & Leaper, 1998).  Stress-induced changes in the immune system that could accelerate wound repair and help prevent infections from taking hold would therefore be adaptive and selected along with other physiological changes that increased evolutionary fitness.

Cells involved in natural immunity do not provide defense against any particular pathogen; rather, they are all-purpose cells that can attack a number of different pathogens and do so in a relatively short time frame (minutes to hours) when challenged.

Bibliography:

  • Priyandarshini S, Aich P. (2012). Effects of Psychological Stress on Innate Immunity and Metabolism in humans:  A Systematic Analysis.
  • Segerstrom SC, Miller GE. (2004). Psychological Stress and the Human Immune System:  A Meta-Analytic study of 30 Years of inquiry. Psychol Bull; 130(3): 601-630.
  • Williams, N. A., & Leaper, D. J. (1998). Infection. In D. J. Leaper & K. G. Harding (Eds.), Wounds: Biology and management (pp. 71– 87). New York: Oxford University Press.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
Green Facts:

Globe_Home 3How can we deliver nutrition in a way that nourishes both planet and people?  See Janine Benyus, Dec 1, 2016 key note talk, Biomimicry as a Cooperative Inquiry, on nature-inspired breakthroughs in agriculture.

Dear Friends

The most frightening fact about Coronary Heart Disease is that for the majority of Americans the first heart attack is sudden and unfortunately deadly (Myerburg, 2012).

How do we prevent and treat coronary heart disease? With the right foods.

The Therapeutic Food Protocol:

Beta Glucan High Potency Synbiotic– 1 heaping tbl twice daily (or two tbl once daily).
Phyto Power– 1 capsules daily
Garlic– 1 capsule daily
Cruciferous Sprouts– 2 capsules daily (preferably between meals).

It is well established in research that soluble beta glucan fibers in the diet will help in the lowering of LDL cholesterol. Two tablespoons of the Beta Glucan High Potency Synbiotic supplies enough beta glucans to significantly lower LDLs, and therefore to place the American Heart Association Seal for cardiovascular health on the label.

The pedigreed strains of probiotic bacteria utilized in the Beta Glucan Synbiotic reduce endotoxin producing bacteria in the gut, as well as, facilitate the tightening of the gut membrane so that endotoxins will not leak into the systemic circulation. Endotoxins can cause chronic systemic inflammation, which then causes a stiffening of the arteries (Erridge, 2011).

Food Science: Let’s discuss cholesterol, endotoxemia, and coronary heart disease.

There is a wide body of evidence that shows places in the world where heart disease is rare, due to dietary habits.

In the famous China Study, researchers investigated the eating habits and incidence of chronic disease among hundreds of thousands of rural Chinese.  In the Guizhou province, a region with half a million people, not a single death could be attributed to coronary artery disease among men under 65 over the course of three years (Campbell et al., 1998).

In Uganda, a country of millions in East Africa, coronary heart disease was described as “almost non-existent (Shaper, 1959). The researchers found that out of 632 people autopsied in St. Louis, Missouri, 136 had died of heart attacks, compared to the East African cohort where out of 632 people autopsied in Uganda only 1 was from a heart attack.

The almost non-existent cases of heart disease among rural Chinese and Africans was attributed to their amazingly low levels of cholesterol, averaging under 150 mg/dL.  Their diets were both centered on plant-based foods, such as grains and vegetables (De Biase, 2007).

Dietary choices at any age may prevent, stop, and even reverse heart disease before it’s too late.

William C. Roberts, editor in chief of the American Journal of Cardiology, states that the only critical risk factor for atherosclerotic plaque buildup is cholesterol, specifically elevated LDL cholesterol in your blood.  It is called bad cholesterol because it’s the vehicle by which cholesterol is deposited into our arteries.  According to Roberts, the optimal LDL cholesterol level is probably 50 to 70 mg/dL.  The population target should therefore be around a total cholesterol level under 150 mg/dL  (Benjamin, 2013).

To drastically reduce LDL cholesterol levels, you need to drastically reduce your intake of three things:  trans fat, which comes from processed foods and naturally from meat and dairy; saturated fat, found mainly in animal products and junk foods; and to a lesser extent dietary cholesterol, found exclusively in animal derived foods, especially eggs (Trumbo, 2011).

Nathan Pritikin, Dean Ornish, and Caldwell Esselstyn, all pioneers in the plant based diet, separately, within their own research, took patients with advance heart disease, and put them on the kind of diet followed by the African and Asians population sited above, and their patients got better— as their LDL cholesterol levels dramatically decreased, so too did the plaque in their arteries, resulting in improved circulation to their heart (Esslestyn, 2010).

Endotoxemia:  A single fast food meal of sausage and egg McMuffins can stiffen your arteries within hours, and this reduced elasticity will last for around 5 hours.  Eating these kinds of meat and fat laden foods daily shifts the gut microflora toward endotoxic producing bacteria, and when these kind of bacteria (or their cell wall parts, such as LPSs) enter into circulation, our immune system reacts causing the stiffening of arteries (Vogel, 1997).  Cardiac patients can experience relief [from angina] when placed on a diet composed primarily of plant foods (Ornish, 1998).

Note: This week I focused on the Beta Glucan High Potency Synbiotic, and its relevance in lowering cholesterol and reducing endotoxemia.  In subsequent emails we will focus on the other three products.

Bibliography:

  • Benjamin MM., & Roberts. WC. (2013). Facts and principles learned at the 19th Annual Williamsburg Conference on Heart Disease. Proc (Bayl Univ Med Cent); 26(2): 124-36.
  • Campbell et al. (1998). Diet, lifestyle, and the etiology of coronary artery disease: the Cornell China Study. Am J Cardio; 82(108): 18T-21T.
  • De Biase et al. (2007). Vegetarian diet and cholesterol and triglycerides levels. Arq. Bras Cardiol; 88(1): 35-9.
  • Erridge, C. (2011). The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4. Br J Nutr; 105(1): 15-23.
  • Esslestyn, C.B. (2010). Is the present therapy for coronary artery disease the radical mastectomy of the twenty-first century? Am J Cardiol; 106(6): 902-4.
  • Myerburg, R.J., & Junttila M.J. (2012). Sudden cardiac death cause by coronary heart disease. Circulation 28; 125 (8): 1043-52.
  • Ornish et al. (1998). Intensive lifestyle changes for reversal of coronary heart disease. JAMA; 280(23): 2001-7.
  • Shaper A.G., & Jones K.W. (1959). Serum-cholesterol, diet, and coronary heart disease in Africans, and Asians in Uganda. Int J Epidemiol; 41(5): 1221-5.
  • Trumbo, P.R., & Shimakawa T. (2011). Tolerable upper intake levels for trans fats, saturated fat, and cholesterol. Nutr Res; 69(5): 270-5.
  • Vogel et al. (1997). Effect of a single high-fat meal on endothelial function in healthy subjects. Am J Cardiol; 79(3): 350-4.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3The Food Revolution Network is committed to healthy, sustainable, humane and conscious food for all. The network aims to empower individuals, build community, and transform food systems to support healthy people and a healthy planet.

Dear Friends

The University of Hawaii Cancer Center assessed that nearly every person in Hawaii will face a diagnosis of cancer either personally or within their family at some point in their life, so says (Hawaii Cancer Facts & Figures, 2010).

The Center’s Mission is to create a world where cancer no longer exists.

Cancer is basically a non-communicable life style disease, and diet is a huge component.  How then can Therapeutic Food supplements help in the prevention cancer?


Therapeutic Foods are plant based supplements. Here is a protocol based on recent studies to support the prevention of cancer

Food Science

Epidemiological studies have consistently linked abundant consumption of fruits and vegetables to a reduction of the risk of developing several types of cancer (Boivin et al., 2009).

Boivin et al., (2009) evaluated the inhibitory effects of extracts isolated from 34 vegetables on the proliferation of 8 different tumor cell lines: breast cancer, brain tumors, kidney cancer, lung cancer, childhood brain tumors, pancreatic cancer, prostate cancer and stomach cancer.

The best by far were vegetables from the Allium (particularly garlic) and the Cruciferous (particularly broccoli) families—inhibiting these cancers almost 100%. The researchers concluded, “The inclusion of cruciferous and allium vegetables in the diet is essential for effective dietary based cancer-preventative strategies.”

Berry fruits have beneficial effects against several types of human cancers; and the evidence is overwhelming.  Their benefits are as follows:

  • Counteract, reduce and repair damage from oxidative stress and inflammation.
  • Regulating carcinogen and xenobiotic metabolizing enzymes, transcription and growth factors, inflammatory cytokines, and cellular signaling pathways of cancer cell proliferation, apoptosis and angiogenesis.
  • Sensitize tumor cells to chemotherapeutic agents by inhibiting pathways that lead to treatment resistance.
  • Provide protection from therapy-associated toxicities.

These anticancer potential benefits are related to their polyphenols (flavonoids, proanthocyanidins, gallotannis, phenolic acids), stilbenoids, lignans and triterpennoids (Seeram NP., 2008).

It is well established that glucans enhance the efficacy of anti-cancer and anti-infection immunotherapy, both in clinical and experimental conditions (Vetvocia V., 2013).

Beta-glucans, naturally occurring polysaccharides, are present as constituents of cell wall of cereal grains, mushrooms, algae, or microbes including bacteria, fungi, and yeast.  Since Pillemer et al. first prepared and investigated zymosan in the 1940s and others followed with the investigation in the 60s and 70s, researchers have well established the significant role of B-glucans on the immune system relative to cancer treament, infection, immunity, and restoration of damaged bone marrow (Yoon TJ., 2013).

The good news is that these plant based foods are shown in many studies to help in the prevention of cancer, and at the same time, help to prevent heart disease and diabetes.

Bibliography:

  • Basu A. Lyons TJ. (2012). Strawberries, blueberries, and cranberries in the metabolic syndrome: clinical perspectives. J Agric Food Chem; 60: 5687-92.
  • Boivin et al. (2009). Antiproliferative and antioxidant activities of common vegetables: A comparative Study. Food Chemistry; 112(20): 374-380.
  • Cao et al. (2014). Garlic-derived allyl sulfides in cancer therapy. Anticancer Agents Med Chem;14(6):793-9.
  • Dinstel R.R., Cascio J., & Koukel S. (2013). The antioxidant level of Alaska’s wild berries: high, higher and highest. Int J Circumpolar Health;72 doi:10.3402/ijch.v7210.21188.
  • Seeram NP. (2008). Berry fruits for cancer prevention: current status and future prospects. J Agric Food Chem; 56(3): 630-5.
  • Steinkellner et al. (2001). Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; 480-481: 285-297.
  • Vetvocla  V. (2013). Synthetic oligossacharides: clinical application in cancer therapy. Anticancer Agents Md Chem; 13(5): 720-4.
  • Yoon et al. 2013. The effects of B-glucans on cancer metastasis. Anticancer Agents Med Chem; 13(5): 699-708.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3VERGE Sep 19-22, 2016 Santa Clara, CA

VERGE Summits are invitation-only, half-day working sessions exploring pressing issues at the intersection of technology and sustainability for companies, governments, utilities and innovators.

garlic

Dear Friends

An old and natural practice to treat vaginal yeast infections is the vaginal douche using a good collection of lactic acid bacteria, such as the Lactobacillus species found within our Original Synbiotic formula, along with a clove of freshly reacted garlic in warmish water. The following protocol makes this an easy process:

We’ve seen in our April 24th Forward Thinking and earlier in the April 12th newsletter that according to current research certain Lactobacillus species taken orally with garlic can be a very effective protocol for treating both vaginosis and candidiasis respectively.  Click on their links to see these references.

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Dear Friends

Bacterial vaginosis (BV) is the most common cause of vaginal symptoms among women.  According to NHANES, data collected between 2001–2004, 29.2% of women ages 14–49 in the United States have BV.  84% of these women with are asymptomatic (Koumans, 2007). Women with BV have an increased risk of miscarriage, preterm labor and delivery, and postpartum infections.

Diagnosis via vaginal swab (wet mount), whiff test, vaginal pH, oligonucleotide probe of DNA of bacteria present are standard. Bacterial vaginosis usually causes the vaginal pH to rise above 4.5 due to the microbial species present. Diagnosis of BV is difficult because of its complex polymicrobial nature indicative of dysbiosis.

BV has high relapse rates and associated complications.  BV diagnosis includes a decrease in vaginal lactobacilli species and increase in the anaerobes population of microbes, including, most commonly Gardnerella vaginosis or A.vaginae (Shipitsyn,2013).  Vaginal bacterial communities differ dramatically between healthy patients and patients with BV, with G. vaginalis present in over 90% of BV cases (Verstraelen & Swidsinski, 2013).  G. vaginalis is up to 70% of asymptomatic healthy women. When G. vaginalis biofilms form they can establish synergistic relationships with other pathogenic anaerobes.

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