Fructo Borate

Dear Friends

Boron is one of the most important minerals in our diet.  How are your boron levels?

The average American’s boron levels are 1 mg/day; and, many studies have shown that the benefits to be derived from boron intake don’t occur until levels of 3 mg/day and above are achieved (Price et al., 2012).
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BioImmersion’s Fructo Borate Complex is a new form of boron supplementation that duplicates the exact nature of the molecular structure of dietary boron found in fruits and vegetables— that is, boron in the food chain is always found bound to carbohydrate (US Patent #5,902,049).

Fructo Borate Complex contains 240 mg of Fructo Borate along with 260 mg of calcium ascorbate to provides 6 mg of elemental boron.  There is 500 mg per vegetarian capsule with 60 capsules per bottle.  There are no excipients of any kind.

Boron is found to be a missing mineral in our daily nutrition as industrialized farming has depleted boron from our soil. Fructo Borate Complex is a complex of calcium, natural fructose, and boron; exactly as it is found in fresh and dried fruits, vegetables, herbs and wine (Miljkovic et al., 2009; Price et al., 2012).  This form of boron is not only safe but also bioavailable compared with most commercial forms of boron (Scorei et al., 2011).

(See the references to the above concluding bullet points in the 2015 paper by Lara Pizzorno entitled, Nothing Boring About Boron)

What are possible benefits from adequate boron intake?

  • Is essential for the growth and maintenance of bone.
  • Greatly improves wound healing.
  • Beneficially impacts the body’s use of estrogen, testosterone, and vitamin D.
  • Boosts magnesium absorption.
  • Reduces levels of inflammatory biomakers, such as hs-CRP and TNF-alpha.
  • Raises levels of antioxidant enzymes, such as SOD, catalase and glutathione peroxidase.
  • Protects against pesticide-induced oxidative stress and heavy-metal toxicity.
  • Improves brain electical activity, cognitive performance, and short-term memory in elders.
  • Influences the formation and activity of key biomolecules, such as SAM-e and NAD.
  • Has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers and multiple and non-Hodgkin’s lymphoma.
  • May help ameliorate the adverse effects of traditional chemotherapeutic agents.

References:

  • Miljkovic et al. (2009). Calcium Fructoborate:  plant-based dietary boron for human nutrition. J Diet Suppl;6:211-226.
  • Pizzorno, L. (2015). Nothing Boring About Boron. Integr Med (Encinitas); 14(4): 35-48.
  • Price et al. (2012). Essential Nutrients of Bone Health and a Review of their Availability in the Average North American Diet. Orthop J;6:143-149.
  • Scorei et al. (2011). A Double-blind, Placebo-Controlled Pilot Study to Evaluate the Effect of Calcium Fructoborate on Systemic Inflammation and Dyslipidemia Markers for Middle-Ased People with Primary Osteoarthritis. Biol Trace Elem Res;144:253-263.
  • Scorei et al. (2011). Calcium Fructoborate—potential anti-inflammatory agent. Biol Trace Elem. Res; doi:10.1007/s12011-011-8972-6.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3We’ve been talking, in our last two emails, about the deficiency of certain minerals in our diet, largely in part because they have become missing in our soil due to faulty farming methods.  If they aren’t in the soil, they won’t be in plants coming from these farms.

The following link is a fabulous and totally inspiring TED talk given by farmer Gabe Brown presenting us with an absolute solution on how we can feed the world if we start farming with nature as he has impressively demonstrated in North Dakota on his massive farm.  The Febuary 2016 talk is called: Regeneration of our Lands: A Producer’s Perspective.

 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends

Osteoporosis on the Rise: What’s missing?

10 million Americans have osteoporosis; and the numbers are predicted to reach 14 million by 2020 (Burge, 2007).

What is missing in our diets and supplementation to have such an increase in the number of people suffering with osteoporosis?

Many studies show that it is our lack of adequate intake of polyphenols from fruits and vegetables, green teas, and some seeds. Berry polyphenols are found to reduce the risk of age related bone loss.

In fact, Hubert et al. (2014) find a positive association of high berry intake and higher bone mass. The researchers recommend the addition of berries to supplement our daily diet.

Their meta-analysis study, Dietary Polyphenols, Berries, and Age Related Bone Loss: A Review Based on Human, Animal and Cell Studies, evaluated human and animal studies and found strong associations between polyphenol intake, reduced fracture risk, increased bone formation markers, and increased BMD (Hubert et al., 2014). For similar studies, see also Welsh, 2012; Hardcastel, 2011; Hooshmand, 2011; Langsetmo, 2011; Arjmandi, 2010; Burge, 2007; Garrett, 1990.

A protocol for added phenols and boron:

Food Science

Strengthen your phenol dietary intake with our High ORAC Synbiotic Formula. The High ORAC includes a collection of berries and fruits with their extracts. High ORAC contains two strong probiotic organisms which in research are shown to tighten the cell junctions in the gut, reducing gut generated chronic inflammation (Ulluwishewa et al., 2011). Chronic inflammation is shown to cause an increase in osteoclast activity resulting in the de-mineralization of the bone (Weitzmann, 2013; Garrett et al., 1990).

Add Fructo Borate Complex to the phenolic and probiotic rich High ORAC to create a highly effective protocol. The Fructo Borate contains carbohydrate bound boron as found in nature. It is highly absorbable and instrumental in enhanving the re-mineralization of the bone (Miljkovic et al., 2004).

Bibliography

  • Arjmandi, B.H.; Johnson, C.D.; Campbell, S.C.; Hooshmand, S.; Chai, S.C.; Akhter, M.P. (2010). Combining fructooligosaccharide and dried plum has the greatest effect on restoring bone mineral density among select functional foods and bioactive compounds. J. Med. Food; 13: 312–319.
  • Burge, R.; Dawson-Hughes, B.; Solomon, D.H.; Wong, J.B.; King, A.; Tosteson, A. (2007). Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J. Bone Miner. Res.22: 465–475.
  • Garrett, I.R.; Boyce, B.F.; Oreffo, R.O.; Bonewald, L.; Poser, J.; Mundy, G.R. (1990). Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivoJ. Clin. Investig; 85: 632–639.
  • Hardcastle, A.C.; Aucott, L.; Reid, D.M.; Macdonald, H.M. (2011). Associations between dietary flavonoid intakes and bone health in a Scottish population. J. Bone Miner. Res: 26: 941–947.
  • Hooshmand, S.; Chai, S.C.; Saadat, R.L.; Payton, M.E.; Brummel-Smith, K.; Arjmandi, B.H. (2011). Comparative effects of dried plum and dried apple on bone in postmenopausal women. Br. J. Nutr; 106: 923–930
  • Hubert, P.A.; Lee, G.L.; Lee, S.K.; Chun, O.K. (2014). Dietary Polyphenols, Berries, and Age-related Bone loss:  A review Based on Human, Animal, and Cell Studies. Antioxidants; 3(1): 144-158.
  • Langsetmo, L.; Hanley, D.A.; Prior, J.C.; Barr, S.I.; Anastassiades, T.; Towheed, T.; Goltzman, D.; Morin, S.; Poliquin, S.; Kreiger, N. (2011). Dietary patterns and incident low-trauma fractures in postmenopausal women and men aged ≥50 y: A population-based cohort study. Am. J. Clin. Nutr; 93: 192–199.
  • Miljkovic D.; Miljkovic N.; McCary M.F. (2004). Up-regulatory impact of boron on Vitamin D function—does it reflect inhibition of 24-hydroxylase?; Medical Hypteses; 63: 1054-1056.
  • New, S.A.; Robins, S.P.; Campbell, M.K.; Martin, J.C.; Garton, M.J.; Bolton-Smith, C.; Grubb, D.A.; Lee, S.J.; Reid, D.M. (2000) Dietary influences on bone mass and bone metabolism: Further evidence of a positive link between fruit and vegetable consumption and bone health? Am J Clin Nutr; 71, 142–151.
  • Ulluwishewa, D; Anderson, R.C.; McNabb W.C.; Moughan, P.J.; Wells, J.M.; Roy, N.C. (2011). Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components. J Nutr; 141(5): 769-776.
  • Weitzmann, M.N. (2013). The Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis. Scientifica; 2013: 29 pages.
  • Welch, A.; MacGregor, A.; Jennings, A.; Fairweather-Tait, S.; Spector, T.; Cassidy, A. (2012). Habitual flavonoid intakes are positively associated with bone mineral density in women. J. Bone Miner. Res; 27: 1872–1878.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Take a quick look and click on this inspiring and beautiful video.  In West Oakland where liquor stores have replaced markets, The Peoples Grocery is creating a healthy alternative, offering access to organic produce.
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends,

“After the age of 50 years, a woman’s risk of dying from a hip fracture is equal to her lifetime risk of dying from breast cancer” (Devirian T., & Volpe S., 2003).

Osteoporosis and Osteoarthritis are of major concern for our aging as well as young population (Newnham RE.,1994; Devirian T., Volpe S., 2003). Osteoarthiritis results from lack of sufficient Boron in our diets (Devirian T., Volpe S., 2003; Helliwell et al., 1996).

Fructo Borate Complex and its natural bioavailable boron supports bone strength and joint integrity (Miljkovic et al., 2009; Scorei et al. (2011).

Boron is found to be a missing mineral in our daily nutrition as industrialized farming has depleted boron from our soil. Fructo Borate Complex is a complex of calcium, natural fructose, and boron; exactly as it is found in fresh and dried fruits, vegetables, herbs and wine (Miljkovic et al., 2009; Price et al., 2012).  This form of boron is not only safe but also bioavailable compared with most commercial forms of boron (Scorei et al., 2011).

1-2 capsules of the Fructo Borate Complex  provides 6-12 mg, which is the researched amount of boron to support healthy strong bone (between 3-10 mg). It also has the ability to reduce inflammation and pain in arthritic joints (Scorei et al., 2011).

References:

  • Newnham RE. (1994). Essentiality of boron for healthy bones and joints. Environ Health Perspect.;102 Suppl 7:83-5
  • Price et al. (2012). Essential Nutrients of Bone Health and a Review of their Availability in the Average North American Diet. Orthop J;6:143-149.
  • Newnham RE. (2003). Boron: Major Cause and Cure for Arthritis. Nutrition; issue 92.
  • Scorei et al. (2011). A Double-blind, Placebo-Controlled Pilot Study to Evaluate the Effect of Calcium Fructoborate on Systemic Inflammation and Dyslipidemia Markers for Middle-Ased People with Primary Osteoarthritis. Biol Trace Elem Res;144:253-263.
  • Helliwell et al. (1996). Elemental analysis of femoral bone from patients with fractured neck of femur or osteoarthritis. Bone;18:151-157.
  • Miljkovic et al. (2009). Calcium Fructoborate:  plant-based dietary boron for human nutrition. J Diet Suppl;6:211-226.
  • Scorei et al. (2011). Calcium Fructoborate—potential anti-inflammatory agent. Biol Trace Elem. Res; doi:10.1007/s12011-011-8972-6.
  • Nielsen F. (1990). Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elm.;9(2):61-9.
  • Devirian T. & Volpe S. (2003). The Physiological Effects of Dietary Boron. Critical Reveiws in Food Science and Nturition; 43(2):210-231.

See Clinical Notes for more.

Yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

Clinical Notes

Osteoarthritis:

Fructo Borate provides 6mg of elemental boron per capsule.  Each boron ion is bound to two fructose molecules.  All food derived boron molecules are bound to carbohydrates.

Take 1 to 2 capsules twice daily depending on the severity of the arthritis.

Osteoporosis:

Surgeons have observed that the bones of patients using boron supplements are much harder to cut than those of patients who had not used boron supplements.  Approximately half the population in the US consumes less than 1mg of boron per day.  Supplementation with 3 mg of boron per day for post menopausal women has demonstrated improved calcium and magnesium retention by the kidneys.

Green Facts:

Globe_Home 3Nature can no longer be viewed merely as a commodity—a storehouse of “resources” for human use and profit.  It must be seen as a partner and model in all human enterprise.  (a quote from Foundation of Deep Ecology)

Dear Friends

Osteoarthritis is a disease condition associated with the aging process; an inability tophytopower-04 copy final 2 successfully manage inflammation in our body. And it is on the rise worldwide (see Nguyen et. al., 2011).

Utilize the Phyto Power for its three varities of wildcrafted Potent Alaskan Rosehip to support the reduction of pain, swelling, and inflammation. See the Therapeutic Foods protocol in Clinical notes below!

Research by Winther et al. (2005) studied 94 patients with osteoarthritis of the hip or knee to ascertain the effectiveness of rosehip (Rosa canina or dog rose). They conclude rosehip helps to reduce pain, swelling and suffering; alleviate symptoms of osteoarthritis and reduce the consumption of rescue medication.  The dosing was 5 capsules (500 mg per capsule) BID for 3 months. (note that dog rose is not a strong rosehip, hence the large dosage).

Cohen M. (2012) conducted a meta-analysis of three randomized controlled trials involving 287 osteoarthritic patients with a median treatment period of 3 months with a standardized rosehip powder.

References:

  • Nguyen et al. (2011) Increasing prevalence of knee pain and symptomatic knee osteoarthritis: survey and cohort data. Ann Intern Med;155(11):725-32.
  • Winther K et al. (2005) A powder made from seeds and shells of a rosehip subspecies (Rosa canina) rduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controled clinical trial. Scnd J Rheumatol; 34(4):302-8.
  • Cohen M. (2012) Rosehip- an evidence based herbal medicine for inflammation and arthritis. Aust Fam Physician; 41(7): 495-8

See in clinical note three strong Therapeutic Food supplements that help with osteoarthritis:(1) Phyto Power, (2) Fructo Borate and (3) No. 7 Systemic Booster.

Yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

Clinical Notes

(1)  Phyto Power: Detox . Activate . Regenerate

Each capsule of Phyto Power contains three ingredients- 200 mgs of three species of wild-crafted Alaskan rosehips, 200 mgs of four species of wild-crafted Alaskan dandelion, and 100 mgs of wild-crafted Alaskan blueberry.  As with all our whole plants selected we analyze for their actives and our rosehip serves as a powerful example of the high actives in all our Therapeutic Food supplements.Rosehip Nutrient Comparison 3

In this bar graph you can see the quantitative difference in the polyphenolic/flavonoid concentration of the Alaskan rosehip compared to the Europeon dog rose. The darker red represents the Alaskan rosehip and the more pink color the European dog rose.

For a more detail analysis click here and scroll down to the newsletter: Phyto Power’s Wildcrafted Alaskan Rosehip.

Take 2 capsules daily.

(2) Fructo Borate: Boron Complex

The Fructo Borate is one of our very first products specifically researched to help with osteoporosis and osteoarthritic type conditions.  See Fructo Borate.

Take 1 to 2 capsules BID depending on the severity of the arthritis.

(3)  No. 7 Systemic Booster:  Multi System Support

No. 7 boosts a high potency blend of our Bulgarian probiotic and its supernatant, plus an important fusion of organic whole fruits and extracts (including tart cherry, cranberry, pomegranate and pineapple) known for their anti-inflammatory effect. We added selected complimentary nutriceuticals including Fructo Borate. It is a foundational product support for multiple sytems within the body.

Take one teaspon daily.  It tastes good too.

Your,

Seann Bardell

Green Facts:

Globe_Home 3The Institute of Public and Environmental Affairs is a registered NGO created by Ma Jun a Chinese environmentalist who was named as one of the 100 most influential persons in the world by Time magazine in May of 2006.  IPE is promoting widespread public participation in environmental governance.

We have added a new topic to our ongoing conversation about good health. Historically, macronutrients, vitamins, minerals, fish oil and fiber have been the center of nutritional advice (McDowell, 2013). But to enhance our diets maximally toward good health we must understand how to utilize phytochemicals (or phytonutrients) from plants. There is a tremendous growing body of research on phytochemicals use for therapeutic purposes.

What we used to call Vitamin P (flavonoids), Vitamin U (glucosinolates and indoles) and Vitamin Q (ubiquinone) were dethroned from vitamin status because specific deficiency symptoms could not be established; and they were simply called phyto-chemicals and classified as secondary metabolites.  What is the definition of a secondary metabolite?

Secondary metabolites are organic compounds that are not directly involved in normal growth, development or reproduction of an organism.  Unlike primary metabolites, absence of secondary metabolites does not result in immediate death, but rather long-term impairment of the organism’s survivability and fecundity. (Fraenkel GS. May 1959. The raison d’Etre of secondary plant substances. Science 129 (3361): 1466-1470)

Long-term impairment of an organism’s survivability sound frighteningly like the very conditions experienced by the increasing millions of people engulfed  in the pandemic of the chronic degenerative disease—CDV, diabetes, cancer, IBD and Alzheimer’s—just to name a few.   It is now understood and acknowledged that the diminished intake of alive colorful foods, fresh fruits and vegetables which are loaded with a diverse array of phytochemicals, could be the cause. Too often, our body is quite simply not fully nourished with plant based nutrients to defend itself against chronic illness (see NutritionFacts.ORG for more information).

Why has the USDA recommended the 5-to-10 servings-a-day of Fruits and Vegetables for all Americans?  Our plate, claim the USDA, should be half filled with vegetables and fruit at each meal.  The scientific evidence now demonstrates that a healthy diet of live foods gives the body what it needs to heal, repair and defend itself.  Health in large part is a matter of feeding the body a diversity of fresh high active foods with rich nutrient density. Your mission then is to help your body with a healthy and diverse plant based diet to fortify your body with nutrients for healthy functioning (for more news on recent research read The Guardian)

Most Americans Eat Much Less than Recommended Amounts of Fruits and Vegetables, Guenther et al. Sept. 2006, J. Amer. Dietetic Assoc. Vol. 106, Issue 9 Pg. 1371-1379.

“Americans need to consume more fruits and vegetables, especially dark green and orange vegetables and legumes.  Nutritionists must help consumers realize that, for everyone older than age 3 years, the new recommendations for fruit and vegetable intakes are greater than the familiar five serving a day.”

It’s not only the baby boomers who are looking in the mirror and thinking wow, I’ve got to slow down this aging process to look and feel better.  People at younger and younger ages are experiencing the debilitating diseases of aging, including those that impair neurological functioning.

Research by L Rossi et al., in their peer-reviewed paper, Benefits from Dietary Polyphenols for Brain Aging and Alzheimer’s Disease, Neurochem Res 2008, Vol. 33 Issue 12, Pg. 2390-2400, add to the mounting body of scientific evidence the awareness that “diets rich in polyphenols are preventative and can even reverse the aging process.”

The researchers summarized the characteristics of the most studied food polyphenols that were shown to have potential anti-aging and brain protective activities.  Foods that due to their polyphenol content were able to scavenge free radicals, chelate redox metals, down regulate inflammatory activities, and of concern to baby boomers, have components that are able to cross the blood-brain barrier and protect for healthy cognitive functioning of the brain.  Rossi et al.’s bottom line is to eat a wide variety of polyphenol rich foods daily.

According to food researchers Elizabeth Devore ScD, Jae Hee Kang ScD, Monique Breteler MD/PhD, and Francine Grodstin ScD (2012), greater intakes of blueberries and strawberries were associated with slower rates of cognitive decline.  Additionally, in further supporting evidence, greater intakes of anthocyanidins and total flavonoids were associated with slower rates of cognitive decline.  This is good news for all of us IF we incorporate this ever-growing body of knowledge seriously into our dietary habits. Devore et al. summary statement couldn’t be clearer:  Higher intake of flavonoids, particularly form berries, appears to reduce rates of cognitive decline in older adults. (Devore EE, Kange JH et al, Dietary Intakes of berries and flavonoids in relation to cognitive decline. Annals of Neurology, Vol. 72, Issue 1, Pg. 135-143, July 2012.)

Clinical Notes:

Speaking of protecting the supporting the cognitive functioning of our brains, our wonderful Blueberry Extract will be back in 2 to 3 weeks.  And, not only that but over the next 2 months we are bringing in 8 to 12 new products, most of which are formulas that we have been diligently researching for two years.  We are very excited about this.  Stay tuned.

As to the above discussion on secondary metabolites that this is the whole point of the Therapeutic Food Supplements.  To enable you to give your body what it needs in the way the phytonutrients to support its healthy functioning.

My typical morning supplementally starts with:

  • 4 tabs of Organic Chlorella
  • 2 capsules Phyto Power
  • 2 capsules Cruciferous Sprouts
  • 4 capsules Ultra Minerals
  • 1 capsule Fructo Borate
  • 1 capsule Blueberry Extract
  • 1 heaping tablespoon  Beta Glucan Synbiotic Formula

 

Taking care of the land, educating children, feeding ourselves in nutritious and delicious ways, and bringing communities together at the table:  this is the common language of Slow Food. It was the values of taste and pleasure that brought me into this movement, but it is the values of social justice and preservation of biodiversity that keep me engaged.  These are the values we need in order to live together on this planet.

(Alice Waters, Vice President, Slow Food International).

©2005 – 2014 BioImmersion Inc. All Rights Reserved