Chromium, Bio-organic

Dear Friends

Trivalent chromium (Cr) is an essential trace element in the metabolism of fats, carbohydrates, and protein. In recent research, Farrokhian et al. (2019) found chromium to be effective for people who have diabetes and also suffer with coronary heart issues. The randomized, double-blind, placebo-controlled trial was done with 64 diabetic patients with heart issues and found that 200 μg chromium increased insulin sensitivity compared with placebo, as well as a significant reduction in C-reactive protein and an elevation in total antioxidant capacity. Chromium also reduced high blood pressure and had even a beneficial impact on weight.

This is very good news, so why add beetroot when chromium is doing so much on its own?

Beet Photo

Beetroot, especially with a high nitrate capacity is found to confer cardiovascular health (Beals et al., 2017). Beetroot has also shown to lower blood pressure as well as help with weight management (Jajja et al., 2014). And lastly, Beetroot with its betalain pigment is a potent antioxidant and anti-inflammatory (Clifford et al., 2015).

In sports, Baily et al. in 2009 found an improved oxygen delivery to the muscles, which helps athlete gain endurance and strength. In 2019, Husmann et al. designed a study to find out if beetroot can reduce muscle fatigue, and found that high nitrate beetroot juice increased exercise ability with less pain.

Beetroot performs so well that we added high nitrate beetroot to our chromium, No 7 Systemic Booster, and of course to the Beta Glucan.

Chr F

Support blood sugar management and cardiovascular health.

Take 1 capsule twice daily.

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References

  • Bailey, S. J., Winyard, P., Vanhatalo, A., Blackwell, J. R., DiMenna, F. J., Wilkerson, D. P., … & Jones, A. M. (2009). Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. Journal of applied physiology107(4), 1144-1155.
  • Beals, J.W., Binns, S.E., Davis, J.L., Giordano, G.R., Klochak, A.L., Paris, H.L. … Bell, C. (2017). Concurrent Beet Juice and Carbohydrate Ingestion: Influence on Glucose Tolerance in Obese and Nonobese Adults. J Nutr Metab, 2017:6436783.
  • Farrokhian, A., Mahmoodian, M., Bahmani, F., Amirani, E., Shafabakhsh, R., & Asemi, Z. (2019). The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease. Biological Trace Element Research, 1-8.
  • Jajja, A., Sutyarjoko, A., Lara, J., Rennie, K., Brandt, K., Qadir, O., Siervo, M. (2014). Beetroot supplementation lowers daily systolic blood pressure in older, overweight subjects. Nutr Res. 34(10), 868-75.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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The Game Changer, produced by James Cameron et al., is a revolutionary new documentary about meat, protein and strength.

It is an absolute must see.  The link above will connect you to their home page.

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

Chronic Disease is the new norm.  We see it all around us:  obesity, metabolic syndrome, fatty liver, diabetes, CVD, cancer, COPD, asthma, Alzheimer’s, Parkinson’s, autism, IBD, IBS,  auto immune disease, arthritis, UTI, and many more.

Doctors, you are our heroes on the frontline in the battle for your patients’ health, and for helping them to prevent their occurrence in the first place.

Key finding in research for the root cause of these chronic illnesses: a continual low-grade inflammation (LGI), termed by scientists as “inflammageing” (Franceschi & Campisi, 2014).

Therapeutic Food Supplements were designed with powerful plant polyphenols, pedigreed probiotic strains  (with their metabolites and microRNAs), and key nutraceuticals to supports the reduction of LGI.  The results are easily measured:  lowering inflammatory markers.

Summary of the Therapeutic Food Offering:

Polyphenol products:  Garlic (antimicrobial, blood pressure regulation), Blueberry Extract (brain and nerve regeneration), Glucosinolates & Sulforaphanes (liver support), Chlorella (absorption of heavy metals and toxins), Be Regular (fiber from ancient seeds – a must have), and Phyto Power (DNA integrity).

Probiotic Products: Supernatant Synbiotic, and Original Synbiotic. Both powerfully effective for GI health

Probiotic + Polyphenols: High ORAC Synbiotic (post antibiotic therapy), Beta Glucan Synbiotic (Cardiovascular and GI support), No. 7 Systemic Booster (designed to combat the root cause of chronic illnesses), and Cranberry Pomegranate Synbiotic (UTI, and prostate support).

Nutraceuticals:  Fructo Borate Complex (bone and joints), Chromium (blood sugar control), Energy (plant ultra minerals), No. 7 (B12, Folate, chromium, D3, and Fructo Borate), Weight-Less (7 keto).

Nutraceuticals + Polyphenols:  Energy (increase ATP levels), Weight-less (weight loss and blood sugar control), and Chromium with high active Beet Root (blood sugar control, increase circulation), No 7 Systemic Booster.

All of our plant materials are eco-farmed, or wild-crafted, selected for their exceptional high-actives, many of which we standardize.  There are no excipients in our Therapeutic Food Supplement (e.g. flowing agents, sweeteners, natural flavors, emulsifiers, etc.).  We are purists in this regard, wanting to give you absolutely the strongest possible natural product for you restoring health.

References:

  • Boivin et al. (2009). Antiproliferative and antioxidant activities of common vegetables: A comparative Study. Food Chemistry; 112(20): 374-380. Article
  • Calder, P. C., Bosco, N., Bourdet-Sicard, R., Capuron, L., Delzenne, N., Doré, J., … & Visioli, F. (2017). Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition. Ageing research reviews40, 95-119. Article
  • Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences69(Suppl_1), S4-S9. Article

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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BioImmersion Therapeutic Food Supplements are certainly a strong tool to facilitate the healing of our bodies; a healthy diet and a clean environment are its necessary partners.  How do we create a healthy environment? A healthy biosphere?  Biomimicry Institute provides some enlightened answers.

 

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Doctor

Over the next week or two we will focus on Heart Disease, still the No. 1 killer in the developed world. (WHO, 2016).

No.1 Cause of Death

The No. 1 killer in the industrial world is Heart Disease.  How can Therapeutic Food help to prevent HD?

In industrialized countries isolated systolic hypertension (ISH) increases steeply with age. Many Americans over the age of 60 have ISH, which is increasingly recognized as a cardiovascular risk. Several studies have shown the strong association between ISH and stroke, kidney failure, cardiovascular morbidity and mortality (Gasowski et al, 2002; Vaccarino et al, 2001).
Reversing or stabilizing the increased arterial stiffness associated with age and disease by targeting any or all of its causes provides of a number of promising new approaches to treatment of systolic hypertension and its sequel, the main causes of mortality and morbidity (Greenwald SE, 2007).

Therapeutic Food supplements magnify the protective benefits of key phytonutrients that support the reduction of ISH.

Therapeutic Food protocol to support protection from ISH:

  • Phyto Power, wild crafted– 2 capsules BID.
  • Be Regular– 2 heaping tbl taken as a meal replacement three times weekly.
  • No. 7 Systemic Booster– 1 tsp at breakfast
  • Beta Glucan High Potency Synbiotic– 1 heaping tbl BID before 2 largest meals.
  • Chromium, Bio-organic with Beet– 1 capsule BID.

Food Science:  In this email we’ll focus on the Phyto Power

Phyto Power copy

Research has shown that the catechin family of flavonoids provide protective phytonutrients particularily from catechin, epicatechins and epigallocatechin gallate.

Endothelial dysfunction, a prognostically relevant key event in atherosclerosis, is characterized by a decreased bioactivity of nitric oxide (NO) and impaired flow-mediated vasodilation (FMD).  Schroeter et al., (2006) showed in healthy male adults that the ingestion of flavanol-rich cocoa was associated with acute elevations in levels of circulating NO species, an enhanced FMD response of conduit arteries, and an augmented microcirculation.

Nagao et al., (2007) observed, in a protocol sample of 240 subjects, that green tea extract high in catechins reduces body fat and cardiovascular risks including a decrease in systolic blood pressure. Low-density lipoprotein cholesterol was also decreased to a greater extent in the catechin group.

Lorenz et al., (2007) investigated the effect of milk in preventing the beneficial effects of tea relative to vascular protection, and found that casein in milk binds to catechins inhibiting their beneficial functioning as antioxidants.  Their conclusion was that milk counteracts the favourable health effects of tea on vascular function.

The wilds of Alaska provide an amazing environment for powerful plants and berries— fertile volcanic ash soil, and a harsh environment that challenges plants to put out high levels of phenols (e.g. flavonoids) to protect themselves.

Notice the different between an Alaskan rosehip and the typical Europe rosehip (dog-rose) in terms of their phytonutrient load.

Flavonoids

  • Quercetin- 10.50 (Alaskan rosehip) verses 1.05 (European rosehip) in mg/g.
  • Hyperoside- 3.03 verses 4.30
  • Kaempferol- 1.62 verses 0.00
  • Isoquercitin- 0.78 verses 3.51
  • Naringenin- 0.26 verses 0.15
  • Rutin- 0.16 verses 0.67
  • Nothofagrin- 0.26 verses 0.07
  • Luteolin- 0.02 verses 0.01
  • Biochanin A- 0.02 verses 0.00

Catechins

  • Catechin- 72.5 verses 35.70
  • Epicatechin- 67.50 verses 33.70
  • gallocatechin- 0.93 verses 0.86
  • epicatechin gallate- 0.45 verses 0.15
  • catechin gallate- 0.25 verses 0.02.

Organic Acids

  • Ellagic acid- 48.30 verses 5.25
  • Gallic acid- 7.85 verses 0.14
  • p- Coumaric acid- 1.54 verses 0.16
  • Protocatachuic acid- 0.97 verses 0.18
  • Caffeic acid- 0.38 verses 0.00
  • Chlorogenic acid- 0.30 verses 0.05.
  • Salicylic acid- 0.22 verses 0.14
  • Fefulic acid- 0.06 verses 0.09

Vitamins

  • Vitamin C- 25.00 verses 10.00
  • Vitamin B3- 1.09 verses 0.19
  • Vitamin B2- 0.08 verses 0.11
  • Vitamin B1- 0.03 verses 0.01
  • Vitamin B6- 0.01 verses 0.00.

Carotenoids

  • Lycopene- 4.89 verses 2.98
  • b-Carotene- 1.15 verses1.53
  • Lutein- 0.21 verses 0.00
  • Zeaxanthin- 0.17 verses 0.19.

Phyto Power’s Alakan Rosehip provides high amount of catechins.  Two capsules gives one the equivalent of two squares of dark chocolate in catechins without the sugar.

References:

  • Dower et al. (2015). Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized double-blind, placebo-controlled, crossover trial. Am J Clin Nutr; 101(5): 914-21.
  • Engler at al. (2004). Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. J Am Coll Nutr; 23:197-204.
  • Greenwald SE. (2007). Ageing of the conduit arteries. J Pathol; 211(2): 157-172.
  • Lorenz et al. 2007. Addition of milk prevents vascular protective effects of tea. European Heart Journal; 28(2): 2219-2223.
  • Nagao et al. (2007). A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity; 15: 1473-1483.
  • Schroeter et al. (2006). Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. PNAS; 103:1024-1029.
  • Tuso et al. (2013) Nutritional Update for Physicians: Plant-Based Diets.
  • WHO (World Health Organization) Cancer Statistics, Sept. (2016).

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Kaiser Permantente has published a remarkable nutritional update for their 15,000 physicians who care for their 10 million members.  Kaiser is now telling doctors that healthy eating may best be achieved with a plant-based diet, defined as a regiment that “encourages whole, plant-based foods and discourages meats, dairy and eggs as well as all refined and processed junk food (Tuso, 2013).”

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

The Chromium is here!

January 9, 2019

Dear Doctor

Our new Chromium has arrived!

The formula 9 times stronger, with 50mcg of elemental trivalent chromium per capsule (6mcg in the old chromium), and with high active beet root, standardized to 10,000ppm nitrate.

The new Chromium is also trivalent:  the ligand on each of the chromium ion ports is a molecule of nicotinic acid (in other words, niacin), in contrast to the nucleotide sugars from brewers’ yeast.

The supplemental facts on the label lists only the weight of the elemental chromium (50mcg), rather than the whole Chromium polynicotinate molecule, which is 500mcg.

The High Active Beet Root is also very powerful: it is standardized to offer a minimum of 10,000ppm plant nitrate. Our bodies convert plant nitrate into nitric oxide, an important nutrient that relaxes blood vessel muscles, opening up circulation. And of course, the high active beet root offers betalains, a unique polyphenolic molecule in beet root with very strong antioxidant, antimicrobial, and anti-inflammatory properties.

Chromium Label Jpeg

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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In this fascinating website you can watch the numbers of births and the number of deaths growth in real time.  See Current World Population.  With the increasing numbers of people reaching sennescense and the mounting pandemic of chronic degenerative diseases, we need a sea-change in how we feed ourselves, to one that brings healthy longevity.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

GS Photo JPEGBroccoli sprouts provide an exceptionally rich source of sulforaphane – a potent inducer of enzymes that protect against chemical carcinogens.  In fact, three-day-old sprouts of broccoli contain 10-100 times higher levels of glucoraphanin (the glucosinolate of sulforaphane) than do the mature broccoli plants.  Broccoli sprouts are the richest natural source for sulforaphanes, and the BioImmersion organic broccoli sprouts selected for the Glucosinolate & Sulforaphane are at the 100 fold level.

Our Glucosinolate & Sulforaphane replaces the Cruciferous Sprout Complex as it supplies 6-8 times the potency of the most important phytochemical, sulforaphane.

Glucosinolate & Sulforaphane comes in two sizes: the 120 capsule size as shown to the right and is in stock now, and the 60 capsule size bottle that will be available in three weeks.  With a dose being 1-2 capsules a day, the larger bottle will give a 2-4 month supply.

Food Science

Broccoli sprouts are a rich source of glucosinolates and isothiocyanates, shown in research to induce phase 2 detoxication enzymes, boost antioxidant status, and protect animals against chemically induced cancer.  Glucosinolates are hydrolyzed by myrosinase (an enzyme found in plants and bowel microflora) to form isothiocyanates.  Glucosinolates are inert as phase 2 enzyme inducers and must be hydrolyzed (break-down) to generate the active isothiocyanates (Shapiro et al., 2001).

Sulforaphane (SFN) is a compound derived from cruciferous vegetables with numerous bioactivities (Su et al., 2018). In fact, Broccoli and especially broccoli sprouts, accumulate significant amounts of the phytonutrient glucoraphanin, which is metabolized in vivo to the biologically active sulforaphane (SFN).  The preponderance of evidence available from in vitro, animal and human studies supports the association of sulforaphane with phase II enzyme induction (James et al., 2012), moreover, SFN strongly displays both anticarcinogenic and anticancer activity by modulating ‘key signaling pathways and genes involved in the induction of apoptosis, cell cycle arrest, and inhibition of angiogenesis’ (Su et al., 2018; see also Peng et al., 2015; Zhang & Tang, 2007).

SFN also upregulates a series of cytoprotective genes by activating nuclear factor erythroid-2- (NF-E2-) related factor 2 (Nrf2), a critical transcription factor activated in response to oxidative stress; Nrf2 activation is also involved in the cancer-preventive effects of SFN (Peng et al., 2015).

Sulforaphane is found in research to have many different health benefits:  Alzheimer’s (Kim et al., 2013), Cardiovascular Disorders (Angeloni et al., 2009), Diabetes (Bahadoran et al., 2012), Asthma- upper airway congestion, (Riedl et al., 2009) and Detoxification in all cells, and in particular with Liver Phase II detoxification enhancement (Riedl et al., 2009).

Sulforaphane (SFN) has been demonstrated to be an effective chemopreventive agent for many years (Shapiro et al., 2001), with positive effects against different kinds of cancers, such as cervical (Chen et al., 2016; Abdull et al., 2013), breast (Peng et al., 2015; Li et al., 2010), bladder (Leone et al., 2017), renal cell carcinoma (Juengel et al., 2016), non-small-cell lung cancer (Wang et al., 2017), and colon and prostate cancers (Clarke et al., 2008; Abdull et al., 2013).

We will continue to examine the research on this important food in the next few weeks.

References

Abdull Razis, A. F., Konsue, N., & Ioannides, C. (2018). Isothiocyanates and Xenobiotic Detoxification. Molecular nutrition & food research62(18), 1700916.

Abdull, R., Ahmad, F., & Noor, N. M. (2013). Cruciferous vegetables: dietary phytochemicals for cancer prevention. Asian Pacific Journal of cancer prevention, 14(3), 1565-1570.

Angeloni, C., Leoncini, E., Malaguti, M., Angelini, S., Hrelia, P., & Hrelia, S. (2009). Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. Journal of agricultural and food chemistry57(12), 5615-5622.

Bahadoran, Z., Tohidi, M., Nazeri, P., Mehran, M., Azizi, F., & Mirmiran, P. (2012). Effect of broccoli sprouts on insulin resistance in type 2 diabetic patients: a randomized double-blind clinical trial. International journal of food sciences and nutrition63(7), 767-771.

Cheng, Y. M., Tsai, C. C., & Hsu, Y. C. (2016). Sulforaphane, a dietary isothiocyanate, induces G2/M arrest in cervical cancer cells through cyclinB1 downregulation and GADD45β/CDC2 association. International journal of molecular sciences, 17(9), 1530.

Clarke, J. D., Dashwood, R. H., & Ho, E. (2008). Multi-targeted prevention of cancer by sulforaphane. Cancer letters, 269(2), 291-304.

Fahey, J. W., Zhang, Y., & Talalay, P. (1997). Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proceedings of the National Academy of Sciences, 94(19), 10367-10372.  http://www.pnas.org/content/94/19/10367

James, D., Devaraj, S., Bellur, P., Lakkanna, S., Vicini, J., & Boddupalli, S. (2012). Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli. Nutrition reviews70(11), 654-665.

Juengel, E., Maxeiner, S., Rutz, J., Justin, S., Roos, F., Khoder, W., … & Blaheta, R. A. (2016). Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro. Oncotarget, 7(51), 85208.

Kim, H. V., Kim, H. Y., Ehrlich, H. Y., Choi, S. Y., Kim, D. J., & Kim, Y. (2013). Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model. Amyloid20(1), 7-12.

Li, Y., Zhang, T., Korkaya, H., Liu, S., Lee, H. F., Newman, B., … & Sun, D. (2010). Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clinical Cancer Research, 1078-0432.

Peng, X., Zhou, Y., Tian, H., Yang, G., Li, C., Geng, Y., … & Wu, W. (2015). Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells. Oncology reports34(3), 1565-1572.

Riedl, M. A., Saxon, A., & Diaz-Sanchez, D. (2009). Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway. Clinical immunology130(3), 244-251.

Shapiro, T. A., Fahey, J. W., Wade, K. L., Stephenson, K. K., & Talalay, P. (2001). Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans.Cancer Epidemiology and Prevention Biomarkers, 10(5), 501-508.  http://cebp.aacrjournals.org/content/10/5/501.long

Su, X., Jiang, X., Meng, L., Dong, X., Shen, Y., & Xin, Y. (2018). Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway. Oxidative Medicine and Cellular Longevity2018.

Wang, D. X., Zou, Y. J., Zhuang, X. B., Chen, S. X., Lin, Y., Li, W. L., … & Lin, Z. Q. (2017). Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3β/β-catenin signaling pathways. Acta Pharmacologica Sinica, 38(2), 241.

Zhang, Y., & Tang, L. (2007). Discovery and development of sulforaphane as a cancer chemopreventive phytochemical. Acta pharmacologica Sinica, 28(9), 1343-1354.


Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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The Environmental Working Group is a most important organization to get to know.  Their mission is to empower people to live healthier lives in a healthier environment. With breakthrough research and education, they drive consumer choice and civic action.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved