Blueberry Extract

Dear Friends

Cognitive decline, including Alzheimer’s, dementia, and other neurological diseases are linked with old age, yet we see these brain/nerve issues in both young and old.

There is a large body of scientific evidence regarding blueberry and blueberry extract’s benefits for cognitive health, protection, and restoration. See Food Science and References below and visit Blueberry Extract and Phyto Power research tab on the product page.

blueberry X 4
Blueberry Extract is the most powerful blueberry extract on the market, our 100% North American blueberry (Vaccinium corymbosum) provides a comprehensive profile of anthocyanins.  Scientists describe blueberries as agents of neuro-regeneration. Research studies show that blueberry and blueberry extract offer a potent and effective brain food to support cognition, memory, and the general health of our nervous system.

  • Blueberry Extract- 1 capsule daily

Phyto Power Photo 10Phyto Power is formulated to support DNA and cellular integrity. A wildcrafted wonder from remote, pure, and fertile regions of Alaska, Phyto Power is filled with biologically high actives, creating a phenolic powerhouse. Blueberries, rose hip, and dandelion are shown in research to help maintain cellular integrity, suppressing or interfering with oncogenic transformation, bolstering antioxidant and anti-inflammatory defenses, and contributing significant re-generative health benefits.

  • Phyto Power- 2 capsules daily

Food Science:

Esteemed research scientists demonstrate that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills  (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).

References:

  • Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641.
  • Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. (2007). Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol Aging, 28, 1187-1194. DOI: 10.1016/j.neurobiolaging.2006.05.031
  • Carey, A.N., Gomes, S.M., & Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet.J Agric Food Chem, 62, 3972-3978. DOI: 10.1021/jf404565s
  • Malin, D.H., Lee, D.R., Goyarzum P., Chang, Y.H., Ennis, L.J., Beckett, E., Shukitt-Hale, B., Joseph, J.A. (2011). Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats.Nutrition, 27, 338-342. DOI: 10.1016/j.nut.2010.05.001  
  • Brewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., & Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, 21, 991-998. DOI: 10.1016/j.jnutbio.2009.08.005
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:10.1080/1028415031000111282
  • Joseph, J.A., Shukitt-Hale, B., & Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence . Ann NY Acd Sci, 1100, 470-85. DOI: 10.1196/annals.1395.052
  • Miller, M.G., Shukitt-Hale, B. (2012). Berry fruit enhances beneficial signaling in the brain. J. Agric. Food Chem,60(23), 5709–5715. DOI: 10.1021/jf2036033
  • Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., & Bickford, P.C. (1999). Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci, 19(18), 8114-21. . Article
  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci.29(41), 12795–12801. DOI:10.1523/JNEUROSCI.3520-09.2009
  • Shukitt-Hale, B., Bielinski, D. F., Lau, F. C., Willis, L. M., Carey, A. N., & Joseph, J. A. (2015). The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. British Journal of Nutrition, 114(10), 1542-154.
  • Shukitt-Hale, B. (2012). Blueberries and neuronal aging. Gerontology, 58, 518-523. DOI: 10.1159/000341101DOI:10.1021/jf072505f

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Food Revolution Summit 2018(April 26 to May 6) is over but you can still tap into the wonderful information and all the great presenters.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends
Blueberry Extract
BioImmersion produces the most potent and pure polyphenolic and probiotic products in the market.

For example: the Blueberry Extract provides intense broad spectrum anthocyanins from the North American blueberry species, Vaccinium corymbosum.

We use 80 pounds of blueberries to create one pound of the purest extract. It is indeed powerful.

Esteemed research scientists demonstrate that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).*

Cognitive decline is becoming a reality for most Baby Boomers as we see our parents suffer with Alzheimer’s or dementia.  Also on the rise is Parkinson’s and other neurological diseases associated with aging … old age. But old age should not be associated with these diseases.

The good news is that there is a growing body of evidence regarding blueberry and specifically blueberry extract’s benefits for cognitive health, protection, and restoration. There is more than hope, there is scientific research to back it up!

We’ve captured much more of the research here in this link to our Blueberry Extract.  Click on the research tab and you’ll be able to access the abstracts and full studies or reviews.

Let’s do a costs/benefits analysis:

The retail price for our Blueberry Extract is $137.94.  There are 60 capsules in a bottle.  The recommended dose for most people is one capsule a day.  Therefore, the daily cost is $2.30, and you have a two month supply.  Is it worth the cost? Yes, the Blueberry Extract is a must do for brain health (read Green Facts for more fun).

References

  • Brewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., & Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, 21, 991-998. DOI: 10.1016/j.jnutbio.2009.08.005
  • Carey, A.N., Gomes, S.M., & Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. J Agric Food Chem, 62, 3972-3978. DOI: 10.1021/jf404565s
  • Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., & Bickford, P.C. (1999). Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci, 19(18), 8114-21. . Article
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:10.1080/1028415031000111282
  • Joseph, J.A., Shukitt-Hale, B., & Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence . Ann NY Acd Sci, 1100, 470-85. DOI: 10.1196/annals.1395.052
  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci. 29(41), 12795–12801. DOI:10.1523/JNEUROSCI.3520-09.2009
  • Malin, D.H., Lee, D.R., Goyarzum P., Chang, Y.H., Ennis, L.J., Beckett, E., Shukitt-Hale, B., Joseph, J.A. (2011). Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats. Nutrition, 27, 338-342. DOI: 10.1016/j.nut.2010.05.001  
  • Miller, M.G., Shukitt-Hale, B. (2012). Berry fruit enhances beneficial signaling in the brain. J. Agric. Food Chem, 60(23), 5709–5715. DOI: 10.1021/jf2036033
  • Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. (2007). Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol Aging, 28, 1187-1194. DOI: 10.1016/j.neurobiolaging.2006.05.031
  • Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641.
  • Shukitt-Hale, B. (2012). Blueberries and neuronal aging. Gerontology, 58, 518-523. DOI: 10.1159/000341101DOI:10.1021/jf072505f
  • Shukitt-Hale, B., Bielinski, D. F., Lau, F. C., Willis, L. M., Carey, A. N., & Joseph, J. A. (2015). The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. British Journal of Nutrition, 114(10), 1542-154.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Putting costs in perspective: It is a matter of priorities

When one goes to Starbucks or a great organic cafe for their favorite coffee (and many of us do it daily) like a double latte, is it worth the $3.50 or more?  Of course, it is.  No questions to ask here; and I’ll say no more.  Only that we need to think of one capsule of Blueberry Extract in this way.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Think better with blueberry

January 22, 2018

Dear Friends

blueberry X 4The CNS (the brain and spinal cord) is particulary vulnerable to oxidative stress, and this vulnerability increases during ageing (Joseph et al, 1998).  In fact as Dr. Joseph put it, “the brain becomes a hot bed of free radical activity in our old age.”

Shukitt-Hale et al. (2015) demonsrated in her research titled, The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing, the powerful cognitive effects by adding blueberry extract and strawberry extract to the diets of senile old rats.

The results showed that rats consuming the berry diets exhibited enhanced motor performance and improved cognition, specifically working memory. In addition, the rats supplemented with blueberry and strawberry diets showed increased hippocampal neurogenesis and expression of insulin-like growth factor 1.

What about research today on the bioavailability of blueberry polyphenols and their beneficial effect with human subjects?

Sandhu et al. (2017) explored the metabolic fate of blueberry anthocyanins after daily (90 days) supplementation of freeze-dried blueberry (equivalent of 1 cup of fresh blueberries).  Their conclusion was that blueberry anthocyanins are absorbed and extensively metablized resulting in the production of various phenolic acid derivatives and their conjugates, all together contributing to the bioavailability and beneficial effects associated with blueberry comsumption.

Miller et al. (2017) studied men and women between the ages of 60 and 75 years. Their findings showed that the group consuming the equivalent of one cup of blueberries daily for 90 days exhibited significantly fewer errors in a verbal learning test and increased mental flexibility on a task-switching test, relative to the placebo group.

BioImmersion powerhouses for polyphenolics supplementation for a healthy brain: 

References

  • Joseph, J. A., Denisova, N., Fisher, D., Shukitt-Hale, B., Bickford, P., Prior, R., & Cao, G. (1998). Age-related neurodegeneration and oxidative stress: putative nutritional intervention. Neurologic clinics, 16(3), 747-755.
  • Joseph, J. A., Denisova, N., Fisher, D., Shukitt‐Hale, B., Bickford, P., Prior, R., & Cao, G. (1998). Membrane and receptor modifications of oxidative stress vulnerability in aging: nutritional considerations. Annals of the New York Academy of Sciences, 854(1), 268-276.
  • Miller, M. G., Hamilton, D. A., Joseph, J. A., & Shukitt-Hale, B. (2017). Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial. European Journal of Nutrition, 1-12.
  • Sandhu, A., Miller, M. G., Shukitt-Hale, B., Edirisinghe, I., & Burton-Freeman, B. (2017). Metabolic Fate of Blueberry Anthocyanins after Chronic Supplementation in Healthy Older Adults. The FASEB Journal, 31(1 Supplement), 646-20.
  • Shukitt-Hale, B., Bielinski, D. F., Lau, F. C., Willis, L. M., Carey, A. N., & Joseph, J. A. (2015). The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. British Journal of Nutrition, 114(10), 1542-154.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3
Five Habits to Heal the Heart of Democracy.The human heart is the first home of democracy. It is where we embrace our questions. Can we be equitable? Can we be generous? Can we listen with our whole beings ….

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Nerve Regeneration

October 6, 2017

Dear Friends

By 2029, more than 20 precent of the total U.S. population will be over the age of 65 (US Census, 2012). By 2050, 30% of the total population in the U.S. will be over 65 years of age. As our aging population expands we see more age-related health disorders, which means we must find measures to prevent or even reverse age-related health disorders (Joseph et al., 2009).

Research has recently shown that consumption of berry fruit, and in particular blueberry, can dramatically impact the aging brain, possibly leading to improved cognition and motor abilities (Joseph et al., 2009).

As you can see both of my above citings come from James Joseph who was for several decades the lead scientist and lab chief for the Laboratory of Neuroscience at the USDA Human Nutrition Research Center on Aging at Tufts University.

It was Dr. Joseph’s research and that of his colleagues who demonstrated that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).
Blueberry Extract
Our Blueberry Extract was designed with Dr. Joseph’s help.  He helped me to convert his work to human consumption.  It is the most powerful blueberry extract on the market, our 100% North American blueberry (Vaccinium corymbosum) provides a comprehensive profile of anthocyanins.

Suggest dose is one capsule a day or as directed by your physician.

References:

  • Brewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., & Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, 21, 991-998. DOI: 10.1016/j.jnutbio.2009.08.005
  • Carey, A.N., Gomes, S.M., & Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. J Agric Food Chem, 62, 3972-3978. DOI: 10.1021/jf404565s
  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci. 29(41), 12795–12801. DOI: 10.1523/JNEUROSCI.3520-09.2009
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:
  • Malin, D.H., Lee, D.R., Goyarzum P., Chang, Y.H., Ennis, L.J., Beckett, E., Shukitt-Hale, B., Joseph, J.A. (2011). Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats. Nutrition, 27, 338-342. DOI: 10.1016/j.nut.2010.05.001
  • Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641. DOI10.1021/jf072505f

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Note:  We are gradually changing all our labels as you can see if you click here on the Supernatant and High ORAC Synbiotics links.  The new label for the Blueberry Extract will have a subtitle and read: Blueberry Extract- Cognitive and Nerve Regeneration. 
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends
Blueberry Extract
Blueberries support cognition and memory. More impressively, blueberries regenerate nerves which is the reason scientists describe blueberries and blueberry extracts as agents of neuro-regeneration.

The many research studies of James Joseph and Barbara Shukitt-Hale have aptly demonstrated the use and application of blueberries as a potential therapeutic agents for reversing and preventing brain aging. Below are a few of their articles.

Learn how to use bluebrries in our research and description tabs.

(Blueberry Extract- the most powerful blueberry extract on the market)

References:

  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci. 29(41), 12795–12801. DOI: 10.1523/JNEUROSCI.3520-09.2009
  • Joseph, J.A., Shukitt-Hale, B., & Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence . Ann NY Acd Sci, 1100, 470-85. DOI: 10.1196/annals.1395.052
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:10.1080/1028415031000111282
  • Shukitt-Hale, B. (2012). Blueberries and neuronal aging.Gerontology, 58, 518-523. DOI: 10.1159/000341101

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
Green Facts:

Globe_Home 3At Slow Food Nation’s July 2017 Conference Alice Waters presented her vision for School Lunch as an Academic Subject— click here to see and hear her most illuminating talk— a program that if implemented would transform our US food system into one that heals as apposed to what we are now all experiencing.
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved