Beta Glucan Synbiotic

Care For Your Heart

November 14, 2017

Dear Friends                                                                                                                                                      

Metabolic Syndrome is considered the leading cause of Heart Disease, the number one killer in the United States.

Three of our Therapeutic Food Supplements are designed with intelligent ingredients that are shown in research to support and help reverse both heart disease and the different conditions associated with metabolic syndrome: Beta Glucan High Potency Synbiotic, Weight-less Systemic Booster, and Organic Chlorella.

  • Beta Glucan High Potency Synbiotic– 1 heaping tbl twice daily before two largest meals.
  • Weight-less:  NO. 4 Systemic Booster– 2 capsules one-half hour before meals. A must do before a high carb meal or snack.
  • Organic Chlorella– 4 tablets taken with meals.

Food Science

Metabolic Syndrome is a disorder affecting approximately one-quarter of the American population. It is in fact considered a worldwide epidemic (NIH: NHLBI, 2015).

The risk factors for Metabolic Syndrome are:  Abdominal obesity, Atherogenic dyslipidemia,
Raised blood pressure, Insulin resistance, Pro-inflammatory state, and Pro-thrombotic state (McCullough 2011, Grundy 2004).
Beta Glucan HZ 3
The Beta Glucan High Potency Synbiotic contains powerful soluble and insoluble fibers and pedigreed strains of probiotics.

Multitude research articles strongly indicate that as dietary fiber goes up the risk of Metabolic Syndrome goes down (Grooms, 2013).

A healthy gut microbiome supports the maintenance of a healthy GI tract membrane barrier function.  Cani et al. (2008) found that bacterial lipopolysaccharide (LPS) levels set the tone of insulin sensitivity and the onset of obesity and diabetes.  An increased gut permeability allowed for the passage of LPS through the gut wall into the systemic circulation.  Thus, lowering plasma LPS concentration could be a potent strategy for the control of metabolic diseases.

Cani et al. (2007, 2007a, 2008, 2009) demonstrated that adding soluble fibers to our daily diet, such as inulin and oat bran beta glucan (containing oligofructose chains found in the Beta Glucan Synbiotic), stimulates the growth of Bifidobacteria sp., which caused a reduction in gut permeability, thereby reducing the levels of LPS systemically, which initiates weight loss, and reduction of metabolic disorders.
WL Low Cropped Jpeg 2
Weight-less is a smart metabolic booster formula – the mix supports weight loss and effectively boosting energy levels.  Weight-less contains wild brown seaweed extracts from kelp and bladderwrack as well as 7-Keto DHEA.  Brown seaweeds are shown in research to lower the glycemic load of complex and simple carbohydrates for better insulin management, as well as offer a power-filled phenolic activity for antioxidant and anti-inflammation effect (Roy et al., 2011). The 7-Keto has been used for many years to turn on fat burning mechanism and offer an effective and safe way to lose weight (Bobyleva et al., 1997).

Together, Weight-less promotes a sustained energy level throughout the day as it modulates carbohydrate digestion and absorption for better weight management and metabolic health (Gabbia et al., 2017; Catarino et al., 2017).
Chlorella HZ
Organic Chlorella– New studies show that Chlorella supports reduction of body fat, improves fat and glucose metabolism, decrease weight, and reduce the risk factors involved with Metabolic Disease.

Mizoguchi et al. (2008) in their research, Nutrigenomic studies of effects of Chlorella on subjects with high-risk factors for lifestyle-related disease, demonstrated that Chlorella intake, in 17 subjects with high risk factors for lifestyle-related disease (obesity, diabetes or hyperlipidemia) and 17 healthy subjects, results in noticeable reductions in body fat percentage, total blood serum cholesterol, and fasting blood glucose levels.

Their research confirmed that Chlorella intake brings about improvements in both fat metabolism and glucose metabolism.  The expression of genes involved in the insulin signaling pathway were also affected by Chlorella vulgaris intake, especially those related to glucose uptake in tissue, providing support for the observation that Chlorella lowers blood glucose levels.

Vecina et al.’s (2014), Chlorella modulates insulin signaling pathway and prevents high-fat-diet- induces insulin resistance in mice, research goal was to evaluate the prophylactic effect Chlorella vulgaris on body weight, lipid profile, blood glucose and insulin signaling in liver, skeletal muscle and adipose tissue of diet-induced obese mice.

Their conclusion was that C. vulgaris supplementation (Chlorella) could be considered as an adjunctive therapy to decrease weight and improve glycemic status and reducing hs-CRP as well as improving liver function in patients with NAFLD.

References:

  • Bobyleva, V., Bellei, M., Kneer, N., & Lardy, H. (1997). The effects of the ergosteroid 7-oxo-dehydroepiandrosterone on mitochondrial membrane potential: possible relationship to thermogenesis. Archives of biochemistry and biophysics, 341(1), 122-128. https://doi.org/10.1006/abbi.1997.9955
  • Cani et al. (2009). Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2 driven improvement of gut permeability. Gut; 58(8): 1091-1103
  • Cani et al. (2008). Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat induced obesity and diabetes in mice, Diabetes; 57:1470-8.
    Cani et al. (2007). Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes; 56:1761-72.
  • Cani et al. (2007a). Selective increases of Bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia; 50: 2374-83.
  • Catarino, M. D., Silva, A., & Cardoso, S. M. (2017). Fucaceae: A source of bioactive phlorotannins. International journal of molecular sciences, 18(6), 1327. Article
  • Gabbia, D., Dall’Acqua, S., Di Gangi, I. M., Bogialli, S., Caputi, V., Albertoni, L., … & De Martin, S. (2017). The Phytocomplex from Fucus vesiculosus and Ascophyllum nodosum Controls Postprandial Plasma Glucose Levels: An In Vitro and In Vivo Study in a Mouse Model of NASH. Marine drugs, 15(2), 41. DOI:10.3390/md15020041
  • Grooms et al. (2013). Dietary Fiber Intake and Cardiometablic Risk among US Adults: NHANES 1999-2010. Am J Med; 126(12): 1059-1067.
  • Grundy, S. M. (2004). Obesity, metabolic syndrome, and cardiovascular disease. The Journal of Clinical Endocrinology & Metabolism, 89(6), 2595-2600.
  • Mizoguchi et al. (2008). Nutrigenomic studies of effects of Chlorella on subjects with high-risk factors for lifestyle-related disease.  J Med Food; 11(3): 395-404.
  • Roy, M. C., Anguenot, R., Fillion, C., Beaulieu, M., Bérubé, J., & Richard, D. (2011). Effect of a commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo. Food research international, 44(9), 3026-3029. https://doi.org/10.1016/j.foodres.2011.07.023
  • Vecina et al. (2014). Chlorella modulate insulin signaling pathway and prevents high-fat diet–induced insulin resistance in mice. Life Sci; 95(1): 45-52.
  • Whaley-Connell, A., McCullough, P. A., & Sowers, J. R. (2011). The role of oxidative stress in the metabolic syndrome. Reviews in cardiovascular medicine, 12(1), 21-29.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.Green Facts:

Globe_Home 3Choosing a healthy diet: Research studies link the emerging global pattern of metabolic syndrome and weight gain to the prevalence of Westernized diet of daily meats, dairy, eggs, simple and processed carbohydrates, and too much sugar (Chai et al., 2017; Azadbakht & Esmaillzadeh, 2009; Lutsey et al., 2008). Although there are conflicting views on dietary guidelines, many scientists and health organizations agree that a focus on whole food plant-based diet is the healthiest guideline for metabolic syndrome and weight loss (Yokoyama et al., 2017; Satija et al., 2017; Kahleova et al., 2017; Hever et al., 2017; Turner et al., 2017; UN Report, 2016; Wang et al., 2015; Tilman & Clark, 2014; WHO/FAO, 2003).*

The Plates, Pyramids, Planet report, compiled in collaboration with the Food Climate Research Network (FCRN) at the University of Oxford, concludes that a plant-based diet has many advantages for health and the environment (UN Report, 2016).*

The type and nature of carbohydrates that improve our metabolic health (obesity, cardiovascular, and diabetes) are comprised of whole plants with fiber (Wright et al., 2017). Whereas low carbs diets with high fat content is shown to increase metabolic syndrome (Lamont et al., 2017; UN Report, 2016).*

A diet that is 80-90% whole food plant-based is highly recommeded by many health organizations and medical universities around the world.

 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Lose Weight

August 2, 2017

Dear Friends                                                                                                                                                                                                            Beta Glucan Photo jpeg 2

Over a billion people in the industrialized world are overweight or obese.  The rising tide of obesity leads to a constellation of disease conditions, from diabetes and heart disease to cancer and non-alcoholic liver disease (WHO, Fact Sheet Update, 2016).

The Beta Glucan High Potency Synbiotic promotes a healthy weight loss due to the gluten free oat beta glucan.*

Chang, H.C., Huang, C.N., Yeh, D.M. … Wang, C.J et al. (2013) conclude in their study entitled, Oat prevents Obesity and Abdominal Fat Distribution, and improves Liver Function in Humans, that consumption of oat reduced obesity, abdominal fat, and improved lipid profiles and liver functions. Taken as a daily supplement, oat could act as an adjuvant therapy for metabolic disorders.

Chang et al. (2013) performed a clinical trial to confirm the effect of oat. Subjects with BMI ≧27 and aged 18–65, were randomly divided into a control (n = 18) and an oat-treated (n = 16) group, taking a placebo or beta glucan-containing oat cereal, respectively, for 12 weeks. The data showed that consumption of oat reduced body weight, BMI, body fat and the waist-to-hip ratio. The researchers showed that profiles of hepatic function, including AST, but especially ALT, were useful resources to help in the evaluation of the liver, since both showed decrements in patients with oat consumption.

Our high potency Original probiotics, along with the B-Glucans, Beetroot, and Inulin provide not only weight-management benefits, but also strong support for heart, liver, GI tract and energy support (see references below).*

*These statements have not been evaluated by the Food & Drug Administration. This products is not intended to diagnose, treat, cure or prevent any disease. The information and citations of research are for informational purposes only. Please be sure to consult your health care provider before taking this or any other product.

References:

  • Cani, P.D., Bibiloni, R., Knauf, C., waget, A., Neyrinck, A.M., Delzenne, N.M., Burcelin, R. (2008). Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat induced obesity and diabetes in mice. Diabetes, 57, 1470-8. DOI:10.2337/db07-1403
  • Cani, P.D., Amar, J., Iglesias, M.A., Poggi, M., Knauf, C., Bastelica, D. … Burelini, R. (2007). Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes, 56, 1761-72. DOI:10.2337/db06-1491
  • Chang, H.C., Huang, C.N., Yeh, D.M., Wang, S.J., Peng, C.H., & Wang, C.J. (2013). Oat prevents obesity and abdominal fat distribution, and improves liver function in human. Plant Foods Hum Nutr, 68(1), 18-23. DOI:10.1007/s11130-013-0336-2
  • Delzenne, N.M., Neyrinck, A.M., Cani, P.D. (2011). Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome. Microb Cell Fact, 10 Suppl 1, S10. DOI: 10.1186/1475-2859-10-S1-S10
  • Maki, .KC., Beiseigel, J.M., Jonnalagadda, S.S., Gugger, C.K., Reeves, M.S., Farmer, M.V., Kaden, V.N., Rains, T.M. (2010). Whole-grain ready-to-eat oat cereal, as part of a dietary program for weight loss, reduces low-density lipoprotein cholesterol in adults with overweight and obesity more than a dietary program including low-fiber control foods. J Am Diet Assoc, 110(2), 205–214.
  • Peng, C.H., Chang, H.C., Yang, M.Y., Huang, C.N., Wang, S.J., Wang, C.J. (2012). Oat attenuate non-alcoholic fatty liver and obesity via inhibiting lipogenesis in high fat-fed rat. J Funct Foods, http://dx.doi.org/10.1016/j.jff.2012.08.003
  • Sáez-Lara, M.J., Robles-Sanchez, C., Ruiz-Ojeda, F.J., Plaza-Diaz, J., Gil, A. (2016). Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials. Int J Mol Sci, 17(6). DOI:10.3390/ijms1706


Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Vermonters are seeing the light!  Green Mountain Power is trying to turn homes, neighborhoods and towns into virtual power plants, to wean them off the electric power grid into total energy self-sufficiency.  A good investment of our time, energy and money?  Think if you had invested in Exxon or Amazon way back when.
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends                                                                                                                                                                                                            Beta Glucan Photo jpeg 2

We are proud to have the Beta Glucan High Potency Synbiotic qualify for the American Heart Association and the FDA “Heart Healthy” seal of approval: improving lipid serum levels.*

The special heat-shearing technology used to liberate the beta-glucans from the oat is patented (US Patent # 6,060,519), and considered by the FDA as a gluten free ingredient (99.98% gluten free).*

The food ingredients in the Beta Glucan formula are chosen carefully for their highest phytonutrient potential. The proprietary mix contains: Organic matrix USDA patented hydrocolloidal beta glucan oat bran (75%), organic whole red beetroot (15%), and organic inulin from chicory fiber (10%).  Advances in microbiome research and technology allow us to grow our hardy and viable pedigreed Original probiotic strains. Our high potency Original probiotics, along with the B-Glucans, Beetroot, and Inulin offer heart healthy properties, GI support with plant fibers and probiotics, weight-management, regularity, and a boost in energy.*

Oats and oat beta glucan have enjoyed a rich cultural historicity and extensive research on heart health  (Andersson & Hellstrand, 2012). From Shaper & Jones (1959) analysis of healthy dietary habits, to the Cornell China study in 1998, and the NIH report in 2015, dietary fibers, whole plant-based foods, and exercise are shown to be essential for a healthy heart. Oats and oat beta glucan are found to reduce serum LDL cholesterol (Ho et al., 2016; Zhu et al., 2015; Whitehead et al., 2014; Wolever et al., 2010), improve liver function (Chang et al., 2013), and promote bowel regularity (Clemens, 2012; Mobley et al., 2014).*

Red beetroot offer a rich source of phyto-nutrients, including ascorbic acid (vitamin C), carotenoids, phenolic acids, and flavonoids. Beets provide a source of dietary nitrate, shown in research to have important implication for heart health (Kapil et al., 2014). Beet’s nutrients are found to prevent oxidation of LDLs, lower triglycerides, and balance blood pressure (Clifford et al., 2015; Eggenbeen et al., 2016; Hobbs et al., 2013). As a multifunctional food, beets also stimulate Phase II liver detox (Vulić et al., 2014), as well as perform a host of other health benefits, including the production of energy for exercise (Murphy et al., 2012), promotion of joint health (Pietrzkowski et al., 2010), Antioxidant (Georgiev et al., 2010), and support for individuals who undergo oncological treatments (Kapadia et al., 2013, 2011; Das et al., 2013).*

The Beta Glucan formula is comprised of our Original probiotics proprietary blend: L. acidophilus, B. longum, L. rhamnosus, L. plantarum, S. thermophilus. Our Original strains of lactic acid bacteria are pedigreed and certified, based on ATCC prototypical strains and confirmed routinely by 16sRNA sequencing to provide highest quality probiotic material. Our strains are hardy, strong, and effective.*

The Original strains are mixed into a proprietary blend of 33 billion cfu/tbl, plus a bonus of 50 billion more probiotic organism added at the time of manufacturing to boost and ensure a high potency. If taken only as a probiotic formula, 1-2 teaspoons will provide a daily dosage of up to 25 billion cfu.

Probiotics are found in research to positively support heart health (Kassaian et al., 2017; Sáez-Lara et al., 2016; DiRienzo, 2014; Delzenne et al., 2011; Saini et al., 2010), with many researchers positing the connection between heart and gut health (Serino et al., 2014; Huang et al., 2013). The Beta Glucan was formulated to nourish both heart and gut into health.*

Inulin from organic chicory root supplies food for probiotic organisms. Probiotic organisms need soluble fiber like inulin to grow and multiply. See Slavin (2013) on fiber as prebiotics, and Dehghan et al. (2013) on inulin and cardiovascular support.*

Together with probiotic, inulin is also found in research to help tighten cell junctions, which is thought to aid against leaky gut syndrome (Cani et al., 2007, 2007a, 2008, 2009).*

The Beta Glucan formula is utilized for bowel regulation. Plant and oat fibers are shown to increase bowel regularity (Schmier et al., 2014).*

The Beta Glucan is multifunctional due to its oat beta glucans, red beetroot, inulin from chicory, and strong probiotic organism. Each ingredient is shown in research to offer heart healthy food, boost energy, and support the GI tract, liver and kidneys, promoting regularity and GI comfort.

Take a look at the references below to engage in learning more about the many health applications scientists have discovered over the years. These shows a fraction of the research findings on oat beta glucan, probiotics, red beetroot, and inulin.*

*These statements have not been evaluated by the Food & Drug Administration. This products is not intended to diagnose, treat, cure or prevent any disease. The information and citations of research are for informational purposes only. Please be sure to consult your health care provider before taking this or any other product.

References:

  • Anderson, K.E., & Hellstrand, P. (2012). Dietary oats and modulation of atherogenic pathways. Mol Nutr Food Res, 56(7), 1003-13. DOI:10.1002/mnfr.201100706
  • Cani, P.D., Pssemiers, S., Van de Wiele, T., Guiot, Y., Everad, A., Rottier, O…. Delzenne, N.M. (2009). Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2 driven improvement of gut permeability. Gut, 58(8), 1091-1103. DOI:10.1136/gut.2008.165886
  • Cani, P.D., Bibiloni, R., Knauf, C., waget, A., Neyrinck, A.M., Delzenne, N.M., Burcelin, R. (2008). Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat induced obesity and diabetes in mice. Diabetes, 57, 1470-8. DOI:10.2337/db07-1403
  • Cani, P.D., Amar, J., Iglesias, M.A., Poggi, M., Knauf, C., Bastelica, D. … Burelini, R. (2007). Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes, 56, 1761-72. DOI:10.2337/db06-1491
  • Cani, P.D., Neyrinck, A.M., Fava, F., Knauf, C., Burcelin, R.G., Tuohy, K.M. … Delzenne, N.M. (2007a). Selective increases of Bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia, 50, 2374-83. DOI:10.1007/s00125-007-0791-0
  • Chang, H.C., Huang, C.N., Yeh, D.M., Wang, S.J., Peng, C.H., & Wang, C.J. (2013). Oat prevents obesity and abdominal fat distribution, and improves liver function in human. Plant Foods Hum Nutr, 68(1), 18-23. DOI:10.1007/s11130-013-0336-2
  • Clemens, R., Kranz, S., Mobley, A.R., Nicklas, T.A., Raimondi, M.P., Rodriguez, J.C., … Warshaw, H. (2012). Filling American’s fiber intake gap: Summary of roundtable to probe realistic solutions with a focus on grain-based foods. J Nutr, 142(7), 1390-1401. DOI:10.3945/jn.112.160176
  • Clifford T, Howatson G, West DJ, Stevenson EJ. (2017). Beetroot Juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. DOI:10.1139/apnm-2017-0238
  • Clifford, T., Howatson, G., West, D.J., Stevenson, E.J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients,7(4):2801-22. DOI: 10.3390/nu7042801
  • Das, S., Fillippone, S.M., Williams, D.S., Das, A., Kukreja, R.C. (2016). Beet root juice protects against doxorubicin toxicity in cardiomyocytes while enhancing apoptosis in breast cancer cells. Mol Cell Biochem, 421(1-2), 89-101.
    DOI: 10.1007/s11010-016-2789-8
  • Das, S., Williams, D.S., Das, A., Kukreja, R.C. (2013). Beet root juice promotes apoptosis in oncogenic MDA-MB-231 cells while protecting cardiomyocytes under doxorubicin treatment. J. Exp. Second. Sci, 2, 1–6. Abstract
  • Dehghan, P., Pourghassem, G.B, & Asgharijafarabadi, M. (2013). Effects of high performance inulin supplementation on glycemic status and lipid profile in women with type 2 diabetes: a randomized, placebo-controlled clinical trial. Health Promot Perspect, 3(1), 55-63. DOI:10.5681/hpp.2013.007
  • Delzenne, N.M., Neyrinck, A.M., Cani, P.D. (2011). Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome. Microb Cell Fact, 10 Suppl 1, S10. DOI: 10.1186/1475-2859-10-S1-S10
  • DiRienzo D.B. (2014). Effect of probiotics on biomarkers of cardiovascular disease: implications for heart-healthy diets. Nutr Rev, 72(1), 18-29. DOI:10.1111/nure.12084
  • Domínguez R, Cuenca E, Maté-Muñoz JL, García-Fernández P, Serra-Paya N, Estevan MC, Herreros PV, Garnacho-Castaño MV. (2017). Effects of Beetroot Juice Supplementation on Cardiorespiratory Endurance in Athletes. A Systematic Review. Nutrients, 9(1). DOI:10.1016/j.jand.2011.12.002
  • Eggenbeen, J., Kim-Shapiro, D.B., Haykowsky, M., Morgan, T.M., Basu, S., Brubaker, P., … Kitzman, D.W. (2016). One week of daily dosing with beetroot juice improves submaximal endurance and blood pressure in older patients with heart failure and preserved ejection fraction. JACC Heart Fail, 4(6), 428-37. DOI: 10.1016/j.jchf.2015.12.013
  • Georgiev, V.G., Weber, J., Kneschke, E.M., Denev, P.N., Bley, T., Pavlov, A.I. (2010). Antioxidant activity and phenolic content of betalain extracts from intact plants and hairy root cultures of the red beetroot Beta vulgaris cv. Detroit dark red.  Plant Foods Hum Nutr, 65(2):105-11. DOI:10.1007/s11130-010-0156-6
  • Ho, H.V., Sievenpiper, J.L., Zurbau, A., Blanco Mejia, S., Jovanovski, E., Au-Yeung, F… Vuksan, V. (2016). The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials. Br J Nutr. 116(8):1369-1382. DOI: 10.1017/S000711451600341X
  • Hobbs, D.A., George, T.W., Lovegrove, J.A. (2013). The effects of dietary nitrate on blood pressure and endothelial function: a review of human intervention studies. Nutr Res Rev, 26(2), 210-22. DOI:10.1017/S0954422413000188
  • Huang, Y., Wang, X., Wang, J., Wu, F., Sui, Y., Yang, L., Wang, Z. (2013). Lactobacillus plantarum strains as potential probiotic cultures with cholesterol-lowering activity. J Dairy Sci, 96(5), 2746-53. DOI:10.3168/jds.2012-6123
  • Kapadia, G.J., Rao, G.S., Ramachandran, C., Iida, A., Suzuki, N., & Tokuda, H. (2013). Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines. J Complement Integr Med., 1. DOI:10.1515/jcim-2013-0007
  • Kapadia, G.J., Azuine, M.A., Rao, G.S, Arai, T., Lida, A., & Tokuda, H. (2011), Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancer cell lines. Anticancer Agents Med Chem, 11(3), 280-4. Abstract
  • Kapil, V., Weitzberg, E., Lundberg, J.O., Ahluwalia, A. (2014). Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health. Nitric Oxide, 38, 45-57. DOI:10.1016/j.niox.2014.03.162
  • Kassaian, N., Aminorroaya, A., Feizi, A., Jafari, P., Amini, M. (2017). The effects of probiotic and synbiotic supplementation on metabolic syndrome indices in adults at risk of type 2 diabetes: study protocol for a randomized controlled trial. Trial, 18(1), 148. DOI:  10.1186/s13063-017-1885-8
  • Mobley, A.R., Jones, J.M., Rodriguez, J., Slavin, J., & Zelman, K.M. (2014). Identifying practical solutions to meet American’s fiber needs: Proceedings from the Food & Fiber Summit. Nutrients, 8(7), 2540-51. DOI:10.3390/nu6072540
  • Murphy, M., Eliot, K., Heuertz, R.M., Weiss, E. (2012). Whole beetroot consumption acutely improves running performance. J Acad Nutr Diet, 112(4), 548-52. DOI: 10.1016/j.jand.2011.12.002
  • Sáez-Lara, M.J., Robles-Sanchez, C., Ruiz-Ojeda, F.J., Plaza-Diaz, J., Gil, A. (2016). Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials. Int J Mol Sci, 17(6). DOI:10.3390/ijms17060928
  • Saini, R., Saini, S., & Sharma, S. (2010). Potential of probiotics in controlling cardiovascular diseases. J. Cardiovasc Dis Res,1(4), 213-214. DOI:  10.4103/0975-3583.74267
  • Schmier, J.K., Miller, P.E., Levine, J.A., Perez, V., Maki, K.C., Rains, T.M., … Alexander, D.D. (2014). Cost savings reduced constipation rates attributed to increased dietary fiber intakes: A decision-analytic model. BMC Public Health, 14-374. DOI: 10.1186/1471-2458-14-374
  • Serino, M., Blasco-Baque, V., Nicolas, S., & Burcelin, R. (2014). Far from the Eyes, Close to the Heart:  Dysbiosis of Gut Microbiota and Cardiovasuclar Consequences. Curr Cardiol Rep, 16(11), 540. DOI:10.1007/s11886-014-0540-1
  • Shaper, A.G., & Jones, K.W. (1959). Serum-cholesterol, diet, and coronary heart disease in Africans, and Asians in Uganda. The Lancet, 275(7102), 534-37. DOI: 10.1093/ije/dys137
  • Slavin, J. (2013). Fiber and prebiotics: mechanism and health benefits. Nutrients, 5(4), 1417-1435. DOI:10.3390/nu5041417
  • Vulić J.J., Ćebović T.N., Čanadanović-Brunet J.M., Ćetković G.S., Čanadanović V.M., Djilas S.M., Tumbas Šaponjac V.T. In vivo and in vitro antioxidant effects of beetroot pomace extracts. J. Funct. Foods. 2014;6:168–175. https://doi.org/10.1016/j.jff.2013.10.003
  • Whitehead A, Beck EJ, Tosh S, Wolever TM. (2014). Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials. Am J Clin Nutr, 100(6), 1413-21. DOI:10.3945/ajcn.114.086108
  • Wolever TM, Tosh SM, Gibbs AL, Brand-Miller J, Duncan AM, Hart V, Lamarche B, Thomson BA, Duss R, Wood PJ  (2010). Physicochemical properties of oat β-glucan influence its ability to reduce serum LDL cholesterol in humans: a randomized clinical trial. Am J Clin Nutr, 92(4):723-32. DOI: 10.3945/ajcn.2010.29174
  • Zhu, X., Sun, X., Wang, M., Zhang, C., Cao, Y., Mo, G., Liang, J., Zhu, S.  (2015). Quantitative assessment of the effects of beta-glucan consumption on serum lipid profile and glucose level in hypercholesterolemic subjects. Nutr Metab Cardiovasc Dis, 25(8), 714-23. DOI:10.1016/j.numecd.2015.04.008

Article by Dohrea Bardell, PhD.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3For those of you who missed Gabe Brown’s TED talk sited in last weeks email, I am offering it up again.  Hear this most exciting evidence for what this big scale North Dakota farmer is proving through using the One Straw Revolution technique. Here’s Gabe:  Regeneration of our Lands: A Producer’s Perspective
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends

Cox and fellow researchers concluded in their paper, Lactobacillus casei Abundance is Associated with Profound Shifts in the Infant Gut Microbiome, that supplementing infants with Lactobacillus casei rhamnosus is positively associated with the promotion of a stable, even, and functionally redundant infant gastrointestinal community; and the reduced risk of atopy and asthma later in life (Cox et al., 2010).

Cox et al. (2010) hypothesize that Lactobacillus casei subsp. Rhamnosus  promote a clustering (a consortium of bugs that work well together) of known probiotic species within the infant gut that are more resistant to perturbation and outgrowth of pathogens (See Food Science below).

A randomized, controlled, double-blind study of 159 newborns, found that early feeding of Lactobacillus casei decrease the rate of atopic dermatitis at age two by 50% (Kalliomaki et al., 2001) and that this protective effect was sustained past infancy (Kalliomaki et al., 2003).

Colonization of the infant gut microorganisms over the first year of life is crucial for development of a balanced immune response; and, early alterations in the gastrointestinal microbiota of neonates has been linked with subsequent development of asthma and atopy in older children (Cox et al., 2010).

Therapeutic Food Protocol for the Neonate LactORN Bottle 2

  • LactORN– 1/8th of a tsp twice a week (one way is to offer LactORN on your fingertip).

Comment:  LactORN contains Lactobacillius casei rhamnosus. LactOrn is blended with inulin derived from organic chicory root, functioning as an important prebiotic fiber.  It has a naturally sweet taste that babies and adults love.

Others of our synbiotic formulas, that have proven to be powerful probiotic formulas for children, are the Original Synbiotic, the Beta Glucan Synbiotic, and the Supernatant Synbiotic.  Click on their links to see their ingredients.  They all contain L. casei rhamnosus plus other good bugs that L. casei promotes a clustering for a healthy and stronger microbiome.

Food Science

Cox et al.’s (2010)  research question centered upon whether the demonstrable positive effects of L. casei rhamnosus was the result of a species-specific increase in relative abundance that accounts for its protective benefits, or, if there is a global effect on the complex GI microbial consortium.  In other words, is it the L. casei rhamnosus all by itself that is doing the disease-reducing work? Or, is it the presence of L. casei that somehow promotes the growth of other good probiotic organisms, and all together as a consortium (cluster) they protect and enhence the baby’s microbiome. They concluded it was the later, it takes a village to raise a baby!

Analysis of the phylogenetic (physical form/identity) differences characteristic of samples with high L. casei rhamnosus revealed a large number of taxa (families of organism) increased in relative abundance in these communities.  These included a number of known beneficial species belonging to the Lactobacillaceae and Bifidobacteriaceae.  Community phylogenetic metrics demonstrated that the promoted taxa were strongly phylogenetically related; and, suggests functional redundancy with GI communities that possess L. casei rhamnosus in high abundance.

In summary the Cox et al. L. casei rhamnosus study demonstrates that high abundance of this probiotic organism is associated with a dramatic change in GI microbial community composition in infants, impacting the relative abundance of a large number of taxa that can be beneficial in reducing the risk of allergy and atopy later in life.

References

  • Cox, M.J., Huang, Y.J., Huang Y.J., Fujimura, K.E., Liu, J.T., McKean, M., Boushey, H.A., Segal, M.R., Brodie, E.L., Cabana, M.D., Lynch, S.V. (2010). Lactobacillus casei Abundance Is Associated with Profound Shifts in the Infant Gut Microbiome. PLOS| one; Tenth Anniversary. Full paper.
  • Kalliomaki, M., Salminen, S., Arvilommi, H., Kero, P., Koskinen, P. et al (2001). Probiotic in primary prevention of atopic disease: a randomized placebo-controlled trial. Lancet; 357: 1076-1079.
  • Kalliomaki, M., Salminen, S., Poussa, T., Arvilommi, H., Isolauri, E. (2003). Probiotics and prevention of atopic disease: 4-year follow-up of a randomized placebo-controlled trial. Lancet; 361: 1869-18

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3
Watch the new trailer An Inconvenient Sequel: Truth to Power.    The sequel to An Inconvenient Truth.  In theatres July 28, 2017.
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

A Smooth Move Every Day

March 13, 2017

Dear Friends

We love it when we have regular and thorough bowel movements.  Be Regular is formulated to accomplish this necessary task.

Be Regular jpeg 2

The five gluten-free organic seeds provide ample fiber to gently detox (absorb toxins) and move the bowels. Taken on a daily basis, Be Regular provides us with fiber and the deeply nutritious life-giving energy of ancient seeds.

The growing evidence in food science on the importance of fiber intake on a daily basis is  conclusive.  Check the Research Tab of Be Regular.  We have summarized a fraction of the bibliography available on the importance of fiber.

How to use Be Regular

  • Add to your morning shake or smoothie.  It will mix in beautifully
  • Add to the Beta Glucan Synbiotic for an added fiber and probiotics for heart health
  • Add to your hot or cold cereal in the morning
  • Add to soups and sauces as a thickening agent
  • Add to home made baked goods

Sincerely yours,

Seann Bardell

Food Science

The public health implications of increasing dietary fiber intake to recommented levels for GI tract health and chronic disease prevention are significant.  Accumulating evidence indicates that greater dietary fiber intakes reduce risk for Type 2 Diabetes, cardiovascular disease, cancer, weight gain, obesity and diverticular disease, as well as constipation (Crowe, 2011; Schmier, 2014).

Bibliography

  • Crowe, F.L., Appleby, P.N., Allen, N.E., Key, T.J. (2011). Diet and risk of diverticular disease in Oxford cohort of European Prospective Investigation into Cancer and Nutrition (EPIC): prospective study of British vegetarians and non-vegetarians. BMJ, 343, d4131 doi: 10.1136/bmj.d4131.
  • Schmier, J.K., Mill, P.E., Levine, J.A., et al. (2014). Cost savings of reduced constipation rates attribted to increased dietary fiber intakes, a decision-analytic model. BMC Public Health, 14, 374.

Green Facts:

Globe_Home 3More that ever we need to tune in, learn from and support organizations like The Environmental Working Group.  Here is their 2017 Dirty Dozen.  EWG’s analysis of tests by the U.S. Deparment of Agriculture found that nearly 70 percent of samples of 48 types of conventionally grown produce were contaminated with pesticide residues.
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved