Urogenital Support

Dear Doctor

We have all been there with sinus infections, sore throats, and some of us with pneumonia.

Antibiotics can do a good job getting rid of the infection; however, antibiotics can make us more vulnerable to opportunist organisms (e.g., Clostridium difficile that causes diarrhea), and disrupt our delicately balanced microbiome in the GI, urogenital, and mouth, causing discomfort in our stomach, constipation or diarrhea, leaky gut, yeast infections, oral thrush and more.

Research finding direct us toward the exact supplemental strategy to offset antibiotics right from the start Cavanagh et al., 2003).

The secret ingredient? The combination of polyphenols and probiotics.

Polyphenols and probiotics work together as one of the best exacting protocols (Goldenberg et al., 2017; Kawabata et al, 2019) to balance gut microbiota– the community of organisms that live in our gut. Polyphenols are actually the preferred food of probiotic organisms!

Even more so, research studies show that these extra potent polyphenols stimulate of the growth of Lactobacilli and Bifidobacteria while inhibiting that of pathogenic bacteria (Cavanagh et al., 2003).

The High ORAC Synbiotic is a comprehensive post antibiotic, with polyphenols from powerful extracts of berries and fruit including Grape Seed Extract, Wild Blueberry, Quercetin, Resveratrol, Wild Bilberry, Cranberry, Tart Cherry, Prune, Raspberry Seed, Strawberry. The Total ORAC assay at 40,000 per capsule – the highest on the market.

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High ORAC has it all – polyphenols, probiotics, prebiotics, and supernatant or postbiotics (Maguire & Maguire 2019). The perfect post or even during antibiotic therapy.

 

References

  • Cani, P.D., Delzenne, N.M. (2011). The gut microbiome as therapeutic target. Pharmacol Ther, 130(2), 202-12.
  • Cavanagh, H. M., Hipwell, M., & Wilkinson, J. M. (2003). Antibacterial activity of berry fruits used for culinary purposes. Journal of medicinal food6(1), 57-61.
  • Goldenberg, J. Z., Yap, C., Lytvyn, L., Lo, C. K. F., Beardsley, J., Mertz, D., & Johnston, B. C. (2017). Probiotics for the prevention of Clostridium difficile‐associated diarrhea in adults and children. The Cochrane Library.
  • Kawabata, K., Yoshioka, Y., & Terao, J. (2019). Role of intestinal microbiota in the bioavailability and physiological functions of dietary polyphenols. Molecules24(2), 370.
  • Maguire, M., & Maguire, G. (2019). Gut dysbiosis, leaky gut, and intestinal epithelial proliferation in neurological disorders: towards the development of a new therapeutic using amino acids, prebiotics, probiotics, and postbiotics. Reviews in the Neurosciences30(2), 179-201.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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The Game Changer, produced by James Cameron et al., is a revolutionary new documentary about meat, protein and strength.

It is an absolute must see. You’ll find it on Netflix.

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

A Deep Nutritional Booster

December 20, 2019

Dear Friends

We all have those days when we realize we have not eaten many veggies, greens, fruits, or wholesome seeds and grains. And let us be clear: That little lettuce salad with the yummy dressing is not what we call deep nutrition.

Our solution is the very famous drink that has helped many people get a needed nutritional boost. Have it as part of your breakfast or afternoon pick me up, it is even a fantastic meal replacement.

A Deep Nutritional Booster Photo
 

The deep nutritional base of the drink: 1 tablespoon of Beta Glucan, 1 tablespoon of Be Regular, and 1 teaspoon of No 7 Systemic Booster. Put in a blender.

This combination has it all: greens, veggies, fruits, berries, seeds, grains, essential nutraceuticals (B12, Folate, Fructo Borate, Vitamin D, and Chromium), 10 probiotics (with Supernatant and ORNs for more immune boosting qualities), and plenty of fiber. The list of ingredients is impressive!

Liquids: 1. Juice – apple, pineapple, prune, watermelon juice, sweet green juices with apple, carrots, and beets, or any berry juice: 1/3 cup of juice & 2/3 cup water (if you need more liquids add a little of both). 2. Coconut water: dilute half/half with water. 3. Nut milks, oat milk, soy, or hemp, (half/half) or use the whole plant-milk. 4. Just water.

Optional: Choose a couple of things to add to your drink. Balance the liquids with items that make the drink thick!

Fruits: 1/2- to Banana, ½ -to 1 cup of frozen or fresh berries, and any fruit you would like (fresh or frozen, e.g., pineapple, melons, mango, peaches, nectarines).  You can add one date (take the pit out) for extra minerals and iron

Greens: a few leaves of spinach

1 tablespoon of Flax Seeds.

1 heaping teaspoon of Bee Pollen – if you are not allergic to bees or honey. Keep in the freezer for freshness. Bee pollen contains a host of nutrients such as antioxidant, protein, vitamins, minerals, enzymes and coenzymes, and more.

Nut butter: A teaspoon of almond butter, peanut butter, cashew butter – add more protein and fiber to the drink.

Play with different combinations to find just the right mixture of things and enjoy this deeply nourishing boost to your health.

 

No. 7 Systemic Booster: the New Longevity

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Beta Glucan Synbiotic:  High Potency Cardiovascular and Metabolic Support

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Be Regular:  Optimal Bowel Health

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Wishing you a happy Hanukkah and Merry Christmas!

Seann and Dohrea

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Game Changer, produced by James Cameron et al., is a revolutionary new documentary about meat, protein and strength.

It is an absolute must see. You’ll find it on Netflix.

.

©2005 – 2019 BioImmersion Inc. All Rights Reserved

Chronic Bladder Infection

November 10, 2019

Dear Friends

Bladder infections can become a chronic condition that requires more and more antibiotics, without seeing a long-term resolution. Living with an irritated and at times painful bladder is very oppressive.

Cranberries and pomegranates have high concentrations of polyphenols with compounds that inhibit pathogenic invaders, such as E. coli and staphylococcus aureus, two known bacteria that cause bladder infections (Bader et al., 2017; Pagliarulo et al., 2016).

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Cranberries have excellent antimicrobial properties that inhibit and manage UTIs (Jensen et al., 2017), while Pomegranates contain 124 different phyto-nutrients and a high concentration of polyphenols that wield an inhibitory effect on pathogenic Staphylococcus aureus. Pomegranates have enjoyed an exalted status since ancient times (Pagliarulo et al., 2016; Parseh et al., 2012).

Together with the “anti-infective activities” of lactobacillus strains (Liévin-Le Moal et al., 2014), and especially for recurrent UTIs (Manzoor et al., 2016), the probiotics, Supernatant and MicroRNAs, add a potent antimicrobial supports to a healthy urogenital system.

Suggested use: 2-4 capsules twice to three times a day for two days, and then lower the dose to 1-2 a day, or as needed.

Cranberry Pomegranate Synbiotic

References:

  • Bader, M. S., Loeb, M., & Brooks, A. A. (2017). An update on the management of urinary tract infections in the era of antimicrobial resistance. Postgraduate medicine, 129(2), 242-258.
  • Jensen, H.D., Carsten, S., Christensen, S.B., & Krogfelt, K.A. (2017). Cranberry juice and combinations of its organic acids are effective against experimental urinary tract infection. Front Microbiol, 8, 542.
  • Liévin-Le Moal, V., & Servin, A. L. (2014). Anti-infective activities of lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents. Clinical microbiology reviews, 27(2), 167-199.
  • Manzoor, A., Ul-Haq, I., Baig, S., Qazi, J. I., & Seratlic, S. (2016). Efficacy of locally isolated lactic acid bacteria against antibiotic-resistant uropathogens. Jundishapur journal of microbiology, 9(1).
  • Pagliarulo, C., De Vito, V., Picariello, G., Colicchio, R., Pastore, G., Salvatore, P., & Volpe, M. G. (2016). Inhibitory effect of pomegranate (Punica granatum L.) polyphenol extracts on the bacterial growth and survival of clinical isolates of pathogenic Staphylococcus aureus and Escherichia coli. Food chemistry, 190, 824-831.
  • Parseh, H., Hassanpour, S., Emam-Djome, Z., Lavasani, A. S., Mahmoodabady, H. Z., CHabok, M., … & Ghahsareh, A. M. (2012, April). Antimicrobial properties of Pomegranate (Punica granatum L.) as a Tannin rich Fruit: a review. In The 1st International and The 4th National Congress on Recycling of Organic Waste in Agriculture. Iran.

 

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Game Changer, produced by James Cameron et al., is a revolutionary new documentary about meat, protein and strength.

It is an absolute must see.  The link above will connect you to their home page.

.

©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Doctor

Bader (2017) update on the status of urinary tract infections (UTIs) emphasizes the growing concern of UTIs caused by antibiotic-resistant Gram-negative bacteria, such as E. coli, Salmonella, Klebeiella– all part of the family Enterobacteriaceae. Treating UTIs with drugs like Fosfomycin tromethamine, amoxicillin, and others are the typical course of action, but what do we do when these drugs do not resolve the UTI?

Proanthocyanidin from Cranberries and Pomegranates have been used for many years as anti-adhesive agents in the treatment of UTI. Gupta et al. (2012) showed in his study that a drug resistant E. coli was sensitive to an extract from cranberries on bladder infection by inhibiting the adhesiveness of multi-drug resistant E. coli to the walls. In 2015 Kaspar et al. assessed the anti-adhesion effect of cranberry extract to improve urinary tract health. More recently, the research and reviews of Lima et al. (2019) and González de Llanoet al. (2019) showed new findings on the efficacy of cranberries against urinary tract infections due to the rich source of phenolic compounds.

Cranberry Pomegranate Synbiotic has the added antimicrobial activity of pomegranate, with probiotics, supernatant and microRNA. 2-4 capsule three times a day for three days as intensive support or until condition resolved.

Order Now: Cranberry Pomegranate Synbiotic

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References

  • Bader, M. S., Loeb, M., & Brooks, A. A. (2017). An update on the management of urinary tract infections in the era of antimicrobial resistance. Postgraduate medicine129(2), 242-258.Abstract
  • González de Llano, D., Liu, H., Khoo, C., Moreno-Arribas, M. V., & Bartolomé, B. (2019). Some New Findings Regarding the Antiadhesive Activity of Cranberry Phenolic Compounds and Their Microbial-Derived Metabolites against Uropathogenic Bacteria. Journal of agricultural and food chemistry67(8), 2166-2174.Article
  • Gupta, A., Dwivedi, M., Mahdi, A.A., Nagana Gowda, G.A., Khetrapal, C.L., Bhandari, M. (2012). Inhibition of adherence of multi-drug resistant E. coli by proanthocyanidin. Urol Res, 40(2), 143-50. DOI: 10.1007/s00240-011-0398-2
  • Kaspar, K.L., Howell, A.B., & Khoo, C. (2015). A randomized, double-blind, placebo-controlled trial to assess the bacterial anti-adhesion effects of cranberry extract beverages.Food Funct, 6(4), 1212-7. DOI: 10.1039/c4fo01018c
  • Lima, M. C., de Sousa, C. P., Fernandez-Prada, C., Harel, J., Dubreuil, J. D., & de Souza, E. L. (2019). A review of the current evidence of fruit phenolic compounds as potential antimicrobials against pathogenic bacteria. Microbial pathogenesis.Abstract
  • Rodríguez-Pérez, C., Quirantes-Piné, R., Uberos, J., Jiménez-Sánchez, C., Peña, A., & Segura-Carretero, A. (2016). Antibacterial activity of isolated phenolic compounds from cranberry (Vaccinium macrocarpon) against Escherichia coli. Food & function7(3), 1564-1573. Article
  • Wafa, B. A., Makni, M., Ammar, S., Khannous, L., Hassana, A. B., Bouaziz, M., … & Gdoura, R. (2017). Antimicrobial effect of the Tunisian Nana variety Punica granatum L. extracts against Salmonella enterica (serovars Kentucky and Enteritidis) isolated from chicken meat and phenolic composition of its peel extract. International journal of food microbiology241, 123-131. DOI: 10.1016/j.ijfoodmicro.2016.10.007

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Transformation to healthy diets by 2050 will require substantial dietary shifts.  Global consumption of fruits, vegetables, nuts and legumes will have to double, and consumption of foods such as red meat and sugar will have to be reduced by more than 50%. A diet rich in plant-based foods and with fewer animal source foods confers both improved health and environmental benefits.  (Walter Willett MD, Harvard T.H. Chan School of Public Health, 2019)

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©2005 – 2019 BioImmersion Inc. All Rights Reserved

Dear Friends

Cellular Senescence means that cells cannot divide due to multiple reasons,  with inflammation posing as one of the greatest. Cellular Senescence hastens the development of chronic diseases like cardiovascular, diabetes, Alzheimer’s, dementias, cancer, immune and kidney dysfunction, IBD, and osteoarthritis among many others.

Current research has shown that certain plant polyphenols (i.e. quercetin and fisetin) are strong senolytic agents (molecules that stop senescence), and have exciting potential  for reducing and preventing senescence, which reduces the risk for developing chronic disease, and even reverses the onset of chronic illnesses and geriatric syndrome.  Research is now focused on the utilization of senolytic molecules in therapies.

The No. 7 Systemic Booster: the New Longevity contains both of these powerful phenolic flavonoids, quercetin and fisetin, within its high-active fruits and vegetables.  Daily dosing at 1 tsp supports the body’s ability to to fight against chronic disease.  (See Further Notes below)

 

No 7 Photo_2 copy

 

Further notes on cellular senescence: 

Chronic low-grade inflammation (LGI) in the body is an etiological factor in chronic disease and it is also a causative force in cells going into senescence.  Cellular senescence is characterized as a state where cells: (1) lose their ability to divide and renew their healthy functionality; (2) become resistant to apoptosis (cell death); and  (3) increase their production of reactive oxygen species (ROS), and secret into their external environment pro-inflammatory cytokines, bradykines, prostenoids, miRNAs, damage-associated molecular pattern proteins (DAMPs), and other pro-inflammatory mediators, chemokines that attract immune cells.  In other words, these cells create more inflammation; more collateral damage that can lead to pathology.  This condition is called a senescence-associated secretory phenotype (SASP).

Senescent cells have been identified at sites of pathology in multiple diseases.  They accumulate in adipose tissue in diabetes and with age-related metabolic dysfunction, osteoarthritic joints, the aorta in vascular hypo-reactivity and atherosclerosis and the lung in idiopathic pulmonary fibrosis.  Transplantation of small numbers senescent cells around the knee joint can cause osteoarthritis (Zhu, Y., et al. 2015).

Therefore, the discovery of strong senolytic molecules  present in certain vegetables and fruits that  are able to delay, prevent, or alleviate a number of chronic  diseases is very exciting. The No. 7 Systemic Booster: the New Longevity is a great starting point to reduce inflammation and deeply nourish our cells with the nutrients they need to function healthily.

References:

  • Kirkland, J. L., & Tchkonia, T. (2017). Cellular senescence: a translational perspective. EBioMedicine, 21, 21-28.
  • Zhu, Y., Doornebal, E. J., Pirtskhalava, T., Giorgadze, N., Wentworth, M., Fuhrmann-Stroissnigg, H., … & Kirkland, J. L. (2017). New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463. Aging (Albany NY), 9(3), 955.
  • Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., … & O’Hara, S. P. (2015). The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. Aging cell, 14(4), 644-658.

To your health,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Our findings here give support for the speculation that these agents [senolytics] may one day be used for treating cardiovascular disease, frailty, loss of resilience, including delayed recovery or dysfunction after chemotherapy or radiation, neurodegenerative disorders, osteoporosis, osteoarthritis, other bone and joint disorders, and adverse phenotypes related to chronologic aging.  Theoretically, other conditions such as diabetes and metabolic disorders, visual impairment, chronic lung disease, liver disease, renal and genitourinary dysfunction, skin disorders, and cancers could be alleviated with senolytics (Zhu,Y. et al., 2017).

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©2005 – 2019 BioImmersion Inc. All Rights Reserved