Neurological Support

Dear Friends

Reduce blood sugar levels with polyphenols!

Americans have a serious problem with chronic hyperglycemia.

Untreated hyperglycemia can cause long-term complications. These include:

  • Cardiovascular disease
  • Nerve damage (neuropathy)
  • Kidney damage (diabetic nephropathy) or kidney failure
  • Damage to the blood vessels of the retina (diabetic retinopathy), potentially leading to blindness
  • Clouding of the normally clear lens of your eye (cataract)
  • Feet problems caused by damaged nerves or poor blood flow that can lead to serious infections, and in some severe cases, amputation
  • Bone and joint problems
  • Skin problems, including bacterial infections, fungal infections and non-healing wounds
  • Teeth and gum infections

What are its causes?  There are multiple, and some may surprise you.

The diet for many Americans contains an overwhelming amount of carbohydrates, with a high proportion coming from added sugars.  To give you an idea, the annual added sugar intake has been reported to range from over 50 lb (median value) in the Dutch population to 142 lb in Americans (Wells & Buzby, 2008).

This means that almost every meal is followed by hyperglycemic conditions.  Recent studies indicate that hyperglycemia induces overproduction of Superoxide Anion (O2-) by the mitochondrial electron transport chain (Node & Inoue, 2009).  O2- is known as a primary free radical, because it converts either spontaneously or through enzymatic assistance into H2O2, peroxynitrite or hydroxyl radical (Gutowski & Kowalczyk, 2014).

Intervention aiming to reduce postprandial hyperglycemia are thus believed to benefit health through prevention of oxidative stress from glucose-overloaded mitochondria.

No. 4 Systemic Booster: Weight-less accomplishes this in two ways: WL Photo 2

  • It contains a powerful mix of wild crafted brown seaweed extracts of Ascophyllum nodosum (kelp) and Fucus vesiculosus (bladderwrack) along with 7-Keto DHEA.
  • These phlorotannin extracts are a class of polyphenols found exclusively in brown seaweed that act on amylase and glucosidase enzymes to optimize post-meal blood glucose and insulin responses.
  • Brown seaweed phlorotannins have a high Total ORAC and the extracts in Weight-less showed the highest antioxidant potency against superoxide anion of all antioxidants tested.
  • Dosage:  take one capsule 20 minutes before your meals.

Since post-meal glycemic fluctuations lead to oxidative stress, these results suggest that Weight-less could have a superior action against free radicals by preventing post-meal hyperglycemia as well as having a direct scavenging action.

References

  • Gutowski, M., & Kowalczyk, S. (2013). A study of free radical chemistry: their role and pathophysiological significance. Acta Biochimica Polonica, 60(1).
  • Node, K., & Inoue, T. (2009). Postprandial hyperglycemia as an etiological factor in vascular failure. Cardiovascular Diabetology, 8(1), 23.
  • Roy, M. C., Anguenot, R., Fillion, C., Beaulieu, M., Bérubé, J., & Richard, D. (2011). Effect of a commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo. Food research international, 44(9), 3026-3029.
  • Wells, H. F., & Buzby, J. C. (2008). Dietary assessment of major trends in US food consumption, 1970-2005. Washington: US Department of Agriculture, Economic Research Service.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

In our next Forward Thinking newsletter we will look at how fat causes insulin resistance and therefore hyperglycemia.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved
Dear Friends

Did you know that polyphenols from berries and plants are the most favored foods for the probiotics genera Lactobacillus and Bifidobacterium in the gut?

The berries and plants enhance the growth of Lactobacillus and Bifidobacterium inside the gut microbiome, while inhibiting many pathogenic organsims.

For example, Possemiers et al.’s (2011)  “The intestinal microbioime: a separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals,” explains that rich polyphenolic molecules from berries and plants are broken down by probiotic organisms into many important sub-molecules that are more bioavailable yet still contain their classic polyphenolic structure to serve the body as antioxidants, anti-inflammatories, antimicrobials, anti cancer, anti diabetes and more  … no wonder berries and plants are the preferred prebiotics foods for the Lactobacillus and Bifidobacteria!

 

Phyto Power– 1 capsule daily
Phyto Power Photo 6

  • Three species of Rosehip, wildcrafted, whole fruit and seeds (100% w/w), refractory dried, three Rosa species, 200mg per capsule.
  • Four species of Dandelion, wildcrafted, aerial parts (90% w/w), root (10% w/w) with flower, refractory dried, four Taraxacum species, 200mg per capsule.
  • Four species of Blueberry, wildcrafted, fruit (>90% w/w), leaves and stem (<5% w/w), refractory dried, four Vaccinium species, 100mg per capsule.

 

 

Original Synbiotic: 1 tsp. dailyOriginal Photo 4

Contains:  20 billion cfu/tsp of certified strains of pedigreed probiotics (L. acidophilus,  B. longum, L. rhamnosus, L. plantarum and S. thermophilus) and 3.5 grams of inulin derived from organic chicory fiber.  Advanced freeze-drying technology.

120 grams/bottle. 4 grams/ tsp.  Dairy free.  Soy free. Gluten free. No excipients.

References

 

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor

Green Facts:

Globe_Home 3Phyto Power is indeed powerful. In fact, Dinstel et al. (2013) found the antioxidant levels of Alaska’s wild berries to be extremely high, ranging from 3 to 5 times higher in ORAC values than cultivated berries from 48 other states. For example, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. When the berries were dehydrated, per gram the ORAC values increased.*
 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Autism and Clostridia

February 24, 2018

Dear Friends

Research ascribes various etiologies to Autism Spectrum Disorder (ASD).  There are exogenous factors such as iatrogenic drugs, pollutants of various kinds, and over use of antibiotics; and there are the endogenous factors such as dysbiosis of the GI Tract, mitochondrial dysfunction, and of course genetics. Interestingly, genetic causation is found to be in the low percentile, whereas dybiosis and mitochondrial dysfunction conditions present major links to ASD.

Let’s focus on dysbiosis.  Overgrowth of clostridia, bacteriodes, and desulfovibrio are all ASD-associated bacterial populations. The overuse of antibiotics enables the clostridial family of bacteria to dominate because their spore forming ability resist many antibiotics and they can easily gain a foothold over good bacteria.

Clostridia is a big producer of the SCFA propionate. Too much propionate in the systemic circulation (which is able to cross the blood-brain barrier) becomes neurological and mitochondrial toxins, disrupting and causing the very symptoms that we see with autistic patients.

There is strong support in the literature for foundational probiotic organisms that reduce the overload of clostridium. These are the organisms we have chosen for our probiotics.

Research is showing that L. plantarum, L. casei rhamnosus, B. longum and even L. acidophilus can put out bacterocins against clostridia.  Doctors who have used our Original Synbiotic and our Supernatant Synbiotic (either one works) found improvement in the behaviors of ASD patients.

I would recommend adding Phyto Power for the high potency of polyphenolics grown in remote Alaskan regions. Phenols are shown in research as antimicrobials, inhibiting many pathogenic organisms including those implicated in ASD, yet at the same time, they enhance both the growth of the Bifido and Lactobacillus genera.

I suggest the following dosage:

Original Synbiotic: up to 1 tsp. daily. With very young patients start with an eight of a tsp and work up slowly adjusting the dosage. Back off just a little from a dosage that causes reaction. You be able to get up to a tsp dose in about a month of gradually ratcheting it up.

As a reminder this product contains L. plantarum, L. casei rhamnosus, L. acidophilus, B. longum and S. thermophiles plus organic chicory root inulin which is very bifido and lacto genic.  Each of the organism are good butyrate produces, and as we know, butyrate helps to heal a leaky gut which is a big problem for ASD patients.

Phyto Power– 1 capsule daily (if they can’t take capsules then just open up the capsule and take the powder directly).

References

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Phyto Power is indeed powerful. In fact, Dinstel et al. (2013) found the antioxidant levels of Alaska’s wild berries to be extremely high, ranging from 3 to 5 times higher in ORAC values than cultivated berries from 48 other states. For example, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. When the berries were dehydrated, per gram the ORAC values increased.*
 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends
Blueberry Extract
BioImmersion produces the most potent and pure polyphenolic and probiotic products in the market.

For example: the Blueberry Extract provides intense broad spectrum anthocyanins from the North American blueberry species, Vaccinium corymbosum.

We use 80 pounds of blueberries to create one pound of the purest extract. It is indeed powerful.

Esteemed research scientists demonstrate that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).*

Cognitive decline is becoming a reality for most Baby Boomers as we see our parents suffer with Alzheimer’s or dementia.  Also on the rise is Parkinson’s and other neurological diseases associated with aging … old age. But old age should not be associated with these diseases.

The good news is that there is a growing body of evidence regarding blueberry and specifically blueberry extract’s benefits for cognitive health, protection, and restoration. There is more than hope, there is scientific research to back it up!

We’ve captured much more of the research here in this link to our Blueberry Extract.  Click on the research tab and you’ll be able to access the abstracts and full studies or reviews.

Let’s do a costs/benefits analysis:

The retail price for our Blueberry Extract is $137.94.  There are 60 capsules in a bottle.  The recommended dose for most people is one capsule a day.  Therefore, the daily cost is $2.30, and you have a two month supply.  Is it worth the cost? Yes, the Blueberry Extract is a must do for brain health (read Green Facts for more fun).

References

  • Brewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., & Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, 21, 991-998. DOI: 10.1016/j.jnutbio.2009.08.005
  • Carey, A.N., Gomes, S.M., & Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. J Agric Food Chem, 62, 3972-3978. DOI: 10.1021/jf404565s
  • Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., & Bickford, P.C. (1999). Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci, 19(18), 8114-21. . Article
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:10.1080/1028415031000111282
  • Joseph, J.A., Shukitt-Hale, B., & Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence . Ann NY Acd Sci, 1100, 470-85. DOI: 10.1196/annals.1395.052
  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci. 29(41), 12795–12801. DOI:10.1523/JNEUROSCI.3520-09.2009
  • Malin, D.H., Lee, D.R., Goyarzum P., Chang, Y.H., Ennis, L.J., Beckett, E., Shukitt-Hale, B., Joseph, J.A. (2011). Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats. Nutrition, 27, 338-342. DOI: 10.1016/j.nut.2010.05.001  
  • Miller, M.G., Shukitt-Hale, B. (2012). Berry fruit enhances beneficial signaling in the brain. J. Agric. Food Chem, 60(23), 5709–5715. DOI: 10.1021/jf2036033
  • Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. (2007). Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol Aging, 28, 1187-1194. DOI: 10.1016/j.neurobiolaging.2006.05.031
  • Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641.
  • Shukitt-Hale, B. (2012). Blueberries and neuronal aging. Gerontology, 58, 518-523. DOI: 10.1159/000341101DOI:10.1021/jf072505f
  • Shukitt-Hale, B., Bielinski, D. F., Lau, F. C., Willis, L. M., Carey, A. N., & Joseph, J. A. (2015). The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. British Journal of Nutrition, 114(10), 1542-154.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Putting costs in perspective: It is a matter of priorities

When one goes to Starbucks or a great organic cafe for their favorite coffee (and many of us do it daily) like a double latte, is it worth the $3.50 or more?  Of course, it is.  No questions to ask here; and I’ll say no more.  Only that we need to think of one capsule of Blueberry Extract in this way.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Nerve Regeneration

October 6, 2017

Dear Friends

By 2029, more than 20 precent of the total U.S. population will be over the age of 65 (US Census, 2012). By 2050, 30% of the total population in the U.S. will be over 65 years of age. As our aging population expands we see more age-related health disorders, which means we must find measures to prevent or even reverse age-related health disorders (Joseph et al., 2009).

Research has recently shown that consumption of berry fruit, and in particular blueberry, can dramatically impact the aging brain, possibly leading to improved cognition and motor abilities (Joseph et al., 2009).

As you can see both of my above citings come from James Joseph who was for several decades the lead scientist and lab chief for the Laboratory of Neuroscience at the USDA Human Nutrition Research Center on Aging at Tufts University.

It was Dr. Joseph’s research and that of his colleagues who demonstrated that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).
Blueberry Extract
Our Blueberry Extract was designed with Dr. Joseph’s help.  He helped me to convert his work to human consumption.  It is the most powerful blueberry extract on the market, our 100% North American blueberry (Vaccinium corymbosum) provides a comprehensive profile of anthocyanins.

Suggest dose is one capsule a day or as directed by your physician.

References:

  • Brewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., & Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, 21, 991-998. DOI: 10.1016/j.jnutbio.2009.08.005
  • Carey, A.N., Gomes, S.M., & Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. J Agric Food Chem, 62, 3972-3978. DOI: 10.1021/jf404565s
  • Joseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration. J. Neurosci. 29(41), 12795–12801. DOI: 10.1523/JNEUROSCI.3520-09.2009
  • Joseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci, 6 (3), 153-162. DOI:
  • Malin, D.H., Lee, D.R., Goyarzum P., Chang, Y.H., Ennis, L.J., Beckett, E., Shukitt-Hale, B., Joseph, J.A. (2011). Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats. Nutrition, 27, 338-342. DOI: 10.1016/j.nut.2010.05.001
  • Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641. DOI10.1021/jf072505f

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Note:  We are gradually changing all our labels as you can see if you click here on the Supernatant and High ORAC Synbiotics links.  The new label for the Blueberry Extract will have a subtitle and read: Blueberry Extract- Cognitive and Nerve Regeneration. 
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved