Metabolic Syndrome Support

Dear Friends

What is the connection between the microbiome and heart heatlh? The microbiome’s metabolites are emerging as the deciding influence for good or bad health. We will dive into this topic in the next couple of weeks (check green facts below).

BG photoAs Dr. JoAnn Manson, professor of medicine at Harvard Medical School and chief of preventive medicine at Brigham and Women’s Hospital says in Healthy gut, Healthy Heart(2018):

There’s a complex interplay between the microbes in our intestines and most of the systems in our bodies, including the vascular, nervous, endocrine, and immune systems.  All of these relationships are highly relevant to cardiovascular health.

What we eat plays a major role in the composition of our gut microbiota.  And we’re learning more about how the substances gut microbes churn out (called metabolites) influence our risk for many chronic diseases, including diabetes, heart disease, and cancer.

The Beta Glucan High Potency Synbiotic: Cardio-Metabolic Support is a great product for seeding the gut with good pedigreed bacteria and prebiotic fibers that strongly support the integrity of the GI tract membrane, support the reduction of GI tract inflammation, support the strengthening and balancing of the immune system.

Probiotics are found in research to positively effect heart health (Kassaian et al., 2017; Sáez-Lara et al., 2016; DiRienzo, 2014; Delzenne et al., 2011; Saini et al., 2010), with many researchers positing the connection between heart and gut health (Serino et al., 2014; Huang et al., 2013).*

Oats and oat beta glucan have enjoyed a rich cultural historicity and extensive research on heart health (Andersson & Hellstrand, 2012).  Oats and oat beta glucan are found to reduce serum LDL cholesterol (Ho et al., 2016; Zhu et al., 2015; Whitehead et al., 2014; Wolever et al., 2010), improve liver function (Chang et al., 2013), and promote bowel regularity (Clemens, 2012; Mobley et al., 2014).*

Red beetroot offer a rich source of phyto-nutrients, including ascorbic acid (vitamin C), carotenoids, phenolic acids, and flavonoids. Beets provide a source of dietary nitrate, shown in research to have important implication for heart health (Kapil et al., 2014). Beet’s nutrients are shown to prevent oxidation of LDLs, lower triglycerides, and balances blood pressure (Clifford et al., 2015; Eggenbeen et al., 2016; Hobbs et al., 2013).*

Inulin from organic chicory root supplies food for the probiotic organisms. Probiotic organisms need fiber to grow and multiply. See Slavin (2013) on fiber as prebiotics, and Dehghan et al. (2013) on inulin and cardiovascular support.*  Together with probiotic, inulin is also found in research to help tighten cell junctions, which is thought to aid against leaky gut syndrome (Cani et al., 2007, 2007a, 2008, 2009).*

The Beta Glucan was formulated to nourish both heart and gut into health.*

Bibliography:

  • Kassaian, N., Aminorroaya, A., Feizi, A., Jafari, P., Amini, M. (2017). The effects of probiotic and synbiotic supplementation on metabolic syndrome indices in adults at risk of type 2 diabetes: study protocol for a randomized controlled trial. Trial, 18(1), 148. DOI: 10.1186/s13063-017-1885-8
  • Sáez-Lara, M.J., Robles-Sanchez, C., Ruiz-Ojeda, F.J., Plaza-Diaz, J., Gil, A.(2016). Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials. Int J Mol Sci, 17(6).DOI: 10.3390/ijms17060928
  • DiRienzo D.B. (2014). Effect of probiotics on biomarkers of cardiovascular disease: implications for heart-healthy diets. Nutr Rev, 72(1), 18-29. DOI: 10.1111/nure.12084
  • Delzenne, N.M., Neyrinck, A.M., Cani, P.D.(2011). Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome. Microb Cell Fact, 10 Suppl 1, S10. DOI: 10.1186/1475-2859-10-S1-S10
  • Saini, R., Saini, S., & Sharma, S. (2010). Potential of probiotics in controlling cardiovascular diseases. J.Cardiovasc Dis Res,1(4), 213-214. DOI: 10.4103/0975-3583.74267
  • Serino, M., Blasco-Baque, V., Nicolas, S., & Burcelin, R. (2014). Far from the Eyes, Close to the Heart: Dysbiosis of Gut Microbiota and Cardiovasuclar Consequences. Curr Cardiol Rep, 16(11), 540. DOI: 10.1007/s11886-014-0540-1
  • Huang, Y., Wang, X., Wang, J., Wu, F., Sui, Y., Yang, L., Wang, Z. (2013). Lactobacillus plantarum strains as potential probiotic cultures with cholesterol-lowering activity. J Dairy Sci, 96(5), 2746-53.DOI: 10.3168/jds.2012-6123
  • Anderson, K.E., & Hellstrand, P. (2012). Dietary oats and modulation of atherogenic pathways. Mol Nutr Food Res, 56(7), 1003-13. DOI: 10.1002/mnfr.201100706
  • Ho, H.V., Sievenpiper, J.L., Zurbau, A., Blanco Mejia, S., Jovanovski, E., Au-Yeung, F… Vuksan, V. (2016). The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials. Br J Nutr. 116(8):1369-1382. DOI: 10.1017/S000711451600341X
  • Zhu, X., Sun, X., Wang, M., Zhang, C., Cao, Y., Mo, G., Liang, J., Zhu, S. (2015).Quantitative assessment of the effects of beta-glucan consumption on serum lipid profile and glucose level in hypercholesterolemic subjects. Nutr Metab Cardiovasc Dis, 25(8), 714-23.DOI: 10.1016/j.numecd.2015.04.008
  • Whitehead A, Beck EJ, Tosh S, Wolever TM. (2014). Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials. Am J Clin Nutr, 100(6), 1413-21.DOI: 10.3945/ajcn.114.086108


Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

Healthy Gut, Healthy Heart:  How the trillions of bacteria in your intestinal tract play a role in your cardiovascular health.

Metabolomics—the study of metabolites—is an emerging scientific discipline of great importance for bettering our understanding of the connection of our GI tract microbiome and the health of our body. More on this topic next week.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

Reduce blood sugar levels with polyphenols!

Americans have a serious problem with chronic hyperglycemia.

Untreated hyperglycemia can cause long-term complications. These include:

  • Cardiovascular disease
  • Nerve damage (neuropathy)
  • Kidney damage (diabetic nephropathy) or kidney failure
  • Damage to the blood vessels of the retina (diabetic retinopathy), potentially leading to blindness
  • Clouding of the normally clear lens of your eye (cataract)
  • Feet problems caused by damaged nerves or poor blood flow that can lead to serious infections, and in some severe cases, amputation
  • Bone and joint problems
  • Skin problems, including bacterial infections, fungal infections and non-healing wounds
  • Teeth and gum infections

What are its causes?  There are multiple, and some may surprise you.

The diet for many Americans contains an overwhelming amount of carbohydrates, with a high proportion coming from added sugars.  To give you an idea, the annual added sugar intake has been reported to range from over 50 lb (median value) in the Dutch population to 142 lb in Americans (Wells & Buzby, 2008).

This means that almost every meal is followed by hyperglycemic conditions.  Recent studies indicate that hyperglycemia induces overproduction of Superoxide Anion (O2-) by the mitochondrial electron transport chain (Node & Inoue, 2009).  O2- is known as a primary free radical, because it converts either spontaneously or through enzymatic assistance into H2O2, peroxynitrite or hydroxyl radical (Gutowski & Kowalczyk, 2014).

Intervention aiming to reduce postprandial hyperglycemia are thus believed to benefit health through prevention of oxidative stress from glucose-overloaded mitochondria.

No. 4 Systemic Booster: Weight-less accomplishes this in two ways: WL Photo 2

  • It contains a powerful mix of wild crafted brown seaweed extracts of Ascophyllum nodosum (kelp) and Fucus vesiculosus (bladderwrack) along with 7-Keto DHEA.
  • These phlorotannin extracts are a class of polyphenols found exclusively in brown seaweed that act on amylase and glucosidase enzymes to optimize post-meal blood glucose and insulin responses.
  • Brown seaweed phlorotannins have a high Total ORAC and the extracts in Weight-less showed the highest antioxidant potency against superoxide anion of all antioxidants tested.
  • Dosage:  take one capsule 20 minutes before your meals.

Since post-meal glycemic fluctuations lead to oxidative stress, these results suggest that Weight-less could have a superior action against free radicals by preventing post-meal hyperglycemia as well as having a direct scavenging action.

References

  • Gutowski, M., & Kowalczyk, S. (2013). A study of free radical chemistry: their role and pathophysiological significance. Acta Biochimica Polonica, 60(1).
  • Node, K., & Inoue, T. (2009). Postprandial hyperglycemia as an etiological factor in vascular failure. Cardiovascular Diabetology, 8(1), 23.
  • Roy, M. C., Anguenot, R., Fillion, C., Beaulieu, M., Bérubé, J., & Richard, D. (2011). Effect of a commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo. Food research international, 44(9), 3026-3029.
  • Wells, H. F., & Buzby, J. C. (2008). Dietary assessment of major trends in US food consumption, 1970-2005. Washington: US Department of Agriculture, Economic Research Service.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

In our next Forward Thinking newsletter we will look at how fat causes insulin resistance and therefore hyperglycemia.

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends

No. 7 brings together the power of the polyphenols with pedigreeds strains of probiotics.
No. 7 Systemic Booster 13
A reduced life span is an outcome associated with many prevalent diseases, including diabetes, obesity, and high blood pressure. In seeking to prevent these diseases, many researchers have looked into potential therapeutic benefits of naturally occurring compounds.

AMP-activated protein kinase (AMPK) is a major metabolic-sensing protein implicated in the prevention of metabolic disorders, or in minimizing the effects thereof, via the regulation of both upstream and downstream target molecules.

In the field of food and nutrition, the current focus lies in the finding of components that activate AMPK. AMPK is a serine/threonine protein kinase and is activated by several natural compounds, including resveratrol, epigallocatechin gallate, berberine, and quercetin. AMPK activation can induce ATP (adenosine triphosphate) generation through pathways such as glycolysis and β-oxidation. By contrast, ATP-consuming pathways, including fatty acid and cholesterol syntheses, and gluconeogenesis, are suppressed by AMPK activation.

The No. 7 Systemic Booster suggestion daily dose:  1 tsp.

Food Science

We used to think of the colon as a storage place for fecal matter, on its way out, whose function was to reabsorb water and minerals.  Now, thru the worldwide research on the human microbiome, we understand that the colon is home to another digestive organ in our body- the GI Microbiome, whose metabolic capacity is 100 fold that of our liver.

A healthy gut microbiome residing in the colon is “the organ” in our body that consumes the fibers (inulins, pectins, beta glucans, resistant starches) and polyphenols in our diet as food, breaking down the longer phenolic chains into shorter ones that are more bioavailable, enabling these phytochemicals to enter into our body and hometically supply their multitude of benefits towards the health of all bodily systems.

Therefore, seeding the digestive system with proven probiotic organisms and bringing in a healthy mix of plants, berries and fruits into your diet is an absolute must for health now and for health long in one’s old age.

References

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

 

Green Facts:

Globe_Home 3

The Game Changers- a teaser for this documentary by James Cameron
(http://gamechangersmovie.com/)

“What I discovered was so revolutionary, with such profound implications for performance, health, and the future of the planet itself, that I had to share it with the world.” Quote from James Wilks

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved

Dear Friends
Original Photo
Who proclaimed first that “All disease begins in the gut”? The first three that will answer correctly, or close enough, will receive the Original Synbiotic formula!

In this day and age medical science with its focus on the human GI tract microbiome and a whole food plant-based diet seems to be calling forth similar sentiments.

Dr. Francis Collins, director of NIH, in a talk entitled Supercharging Science for the Superorganism, said that we are a chimera-like creature, governed by our 10 trillion human cells and their 22,000 genes and the microbiome community in the GI tract — all 100 trillion of them with their 2 to 8 million genes (2015).

Possemier et al. (2010) has said it well when his team suggested we  consider the complex microbial ecosystem in our intestines as a separate organ within the body.

Martinez et al (2017) weighed in on this with their research paper entitled- Western diets, gut dysbiosis, and metabolic diseases: Are they linked? And indeed dysbiosis from Western diets is believed to be one of the reason obesity afflicts 36.5% of the US population and 600 million individuals world-wide.

The World Health Organization (WHO), Harvard Medical School, Kaiser Permantente, just to name a few, are all calling for a change of our dietary habits to one that focuses on a whole food plant based diet. Did you also know that probiotics love plants’ fiber and polyphenols? Plants are their most important source of food, and plants are also our most important source of foods.

See below in Green Facts the teaser on the new documentary by Cameron, The Game Changers.

At BioImmersions, we focus on probiotics,  plant polyphenols, fiber, and phytonutrients of eco-farmed or wildcrated whole foods. Our supplements are powerfully concentrated. We all recognize that it is difficult to change a diet that we are addicted to.  Here are two of our products that can make a big difference in the health of your gut microbiome, which translates to health in the whole body.

Phyto Power– 1 capsule daily
Phyto Power Photo 6

  • Three species of Rosehip, wildcrafted, whole fruit and seeds (100% w/w), refractory dried, three Rosa species, 200mg per capsule.
  • Four species of Dandelion, wildcrafted, aerial parts (90% w/w), root (10% w/w) with flower, refractory dried, four Taraxacum species, 200mg per capsule.
  • Four species of Blueberry, wildcrafted, fruit (>90% w/w), leaves and stem (<5% w/w), refractory dried, four Vaccinium species, 100mg per capsule.

 

 

Original Synbiotic: 1 tsp. dailyOriginal Photo 4

20 billion cfu/tsp of certified strains of pedigreed probiotic with Therapeutic Foods in a synbiotic formula of L. acidophilus, B. longum, L. rhamnosus, L. plantarum, S. thermophilus and 4 grams of inulin derived from organic chicory fiber. Advanced freeze-drying technology. 120 grams/bottle. 4 grams/ tsp. Dairy free.  Soy free. Gluten free. No excipients.


References


Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3

The Game Changers- a teaser for this documentary by James Cameron
(http://gamechangersmovie.com/)

“What I discovered was so revolutionary, with such profound implications for performance, health, and the future of the planet itself, that I had to share it with the world.”  Quote from James Wilks

 

©2005 – 2018 BioImmersion Inc. All Rights Reserved
Dear Friends

Did you know that polyphenols from berries and plants are the most favored foods for the probiotics genera Lactobacillus and Bifidobacterium in the gut?

The berries and plants enhance the growth of Lactobacillus and Bifidobacterium inside the gut microbiome, while inhibiting many pathogenic organsims.

For example, Possemiers et al.’s (2011)  “The intestinal microbioime: a separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals,” explains that rich polyphenolic molecules from berries and plants are broken down by probiotic organisms into many important sub-molecules that are more bioavailable yet still contain their classic polyphenolic structure to serve the body as antioxidants, anti-inflammatories, antimicrobials, anti cancer, anti diabetes and more  … no wonder berries and plants are the preferred prebiotics foods for the Lactobacillus and Bifidobacteria!

 

Phyto Power– 1 capsule daily
Phyto Power Photo 6

  • Three species of Rosehip, wildcrafted, whole fruit and seeds (100% w/w), refractory dried, three Rosa species, 200mg per capsule.
  • Four species of Dandelion, wildcrafted, aerial parts (90% w/w), root (10% w/w) with flower, refractory dried, four Taraxacum species, 200mg per capsule.
  • Four species of Blueberry, wildcrafted, fruit (>90% w/w), leaves and stem (<5% w/w), refractory dried, four Vaccinium species, 100mg per capsule.

 

 

Original Synbiotic: 1 tsp. dailyOriginal Photo 4

Contains:  20 billion cfu/tsp of certified strains of pedigreed probiotics (L. acidophilus,  B. longum, L. rhamnosus, L. plantarum and S. thermophilus) and 3.5 grams of inulin derived from organic chicory fiber.  Advanced freeze-drying technology.

120 grams/bottle. 4 grams/ tsp.  Dairy free.  Soy free. Gluten free. No excipients.

References

 

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor

Green Facts:

Globe_Home 3Phyto Power is indeed powerful. In fact, Dinstel et al. (2013) found the antioxidant levels of Alaska’s wild berries to be extremely high, ranging from 3 to 5 times higher in ORAC values than cultivated berries from 48 other states. For example, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. When the berries were dehydrated, per gram the ORAC values increased.*
 

©2005 – 2018 BioImmersion Inc. All Rights Reserved