Inflammatory Support

Dear Friends

Original copy
The Original Synbiotic is a daily probiotic for the whole family.

The Original probiotics are researched pedigreed strains of lactic acid bacteria that support the development of a healthy GI tract microbiome.

A healthy gut microbiome is dependent on strong and proven probiotics, such as the Original strains. The Original Synbiotic provides a powerful symbiotic combination of Lactobacillus acidophilus (ATCC 4356), Streptococcus thermophilus (ATCC 19258), Lactobacillus plantarum (ATCC 8014), Lactobacillus rhamnosus (ATCC 7469) and Bifidobacterium longum (ATCC 15707).

Our chosen probiotics are foundational ATCC strains shown in research to work together with human cells to perform many functions in the body. For example, these probiotic strains help the digestive system, support and balance the immune system, and enhance our nervous system by producing neurotransmitters. They reinforce the GI barrier function to protect us from xenobiotics and pathogens, even binding heavy metals. Moreover, they neutralize carcinogens such as those caused by heterocyclic amines found in blackened meat and elements such as nitrosamines in sausage. By acidifying the epithelial membrane, they enable the absorption of minerals such as calcium and magnesium more readily. And lastly, our chosen strains also support the important task of daily regularity (Syngia et al., 2016; Hardy et al., 2013; Figueroa‐González et al., 2011; Ng et al., 2009).

The Original Synbiotic suggested daily dose: one tsp daily.

Of the many beneficial functions needed to be performed by our probiotic friends, colonizing the GI tract membrane and thereby protecting from our body from pathogens and xenobiotics, is very important. Check out these studies on colonization (Toscano et al., 2017; Underwood et al., 2015; Panigrahi et al., 2008; De Champs et al., 2003; Sarem- Damerdji et al., 1995).

See the Original Synbiotic Monograph.

References:

  • De Champs, C., Maroncle, N., Balestrino, Damien., Rich, C., Forestier, C. (2003). Persistence of Colonization of Intestinal Mucosa by A Probiotic Strain, Lactobacillus casei subsp rhamnosus Lcr35, after Oran Consumption. J Com Microbiol; 41(3): 1270-1273.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150315/
  • Figueroa‐González, I., Quijano, G., Ramírez, G., & Cruz‐Guerrero, A. (2011). Probiotics and prebiotics—perspectives and challenges. Journal of the Science of Food and Agriculture, 91(8), 1341-1348.
  • Hardy, H., Harris, J., Lyon, E., Beal, J., & Foey, A. D. (2013). Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology. Nutrients, 5(6), 1869-1912.
  • Ng, S. C., Hart, A. L., Kamm, M. A., Stagg, A. J., & Knight, S. C. (2009). Mechanisms of action of probiotics: recent advances. Inflammatory bowel diseases, 15(2), 300-310.
  • Panigrahi, P., Pradhan, L., Mohapatra, S.S., Misra, P.R., Johnson, J.A., Chaudhry, R., Taylor, S., Hanse, N.I., Gewolb, I.H. (2008). Long-term colonization of a Lactobacillus plantarum synbiotic preparation in the neonatal gut. J Pediatr Gastroenterol Nutr; 47(1):45-53. https://www.ncbi.nlm.nih.gov/pubmed/18607268
  • Sarem-Damerdji, L., Sarem, F., Marchal, L., Micolas, J.P. (1995). In vitro colonization ability of human colon mucosa by exogenous Lactobacillus strains. FEMS Microbiology Letters; 131(2):133-137. https://academic.oup.com/femsle/article-abstract/131/2/133/524865/In-vitro-colonization-ability-of-human-colon?redirectedFrom=PDF
  • Syngai, G. G., Gopi, R., Bharali, R., Dey, S., Lakshmanan, G. A., & Ahmed, G. (2016). Probiotics-the versatile functional food ingredients. Journal of food science and technology, 53(2), 921-933. doi:  10.1007/s13197-015-2011-0
  • Toscano, M., De Grandi, R., Stronati, L., De Vecchi, E., & Drago, L. (2017). Effect of Lactobacillus rhamnosus HN001 and Bifidobacterium longum BB536 on the healthy gut microbiota composition at phyla and species level: A preliminary study. World journal of gastroenterology, 23(15), 2696.
  • Underwood, M. A., German, J. B., Lebrilla, C. B., & Mills, D. A. (2015). Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut. Pediatric research, 77, 229.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350908/

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3In today’s world the level of assault on our bodies from pollution, pathogens, and stress is so high that we need powerful food supplements.  Our bodies, after all, know exactly what and how to utilize food for therapeutic purposes.

At BioImmersion, we created the Therapeutic Food Supplement line with a new medical framework in mind: the power and intelligence of food. Our Therapeutic Foods are indeed potent food supplements that behave intelligenly in the body – repairing, healing, protecting and preventing.

 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Weight-Less

September 22, 2017

Dear Friends                                                                                                                                                      WL Low Cropped Jpeg

Recent research has shown the link between chronic hyperglycemia, oxidative stress, and weight gain. Hyperglycemia puts our body into a state of oxidative stress, which leads to many pathologies such as diabetes mellitus, obesity, cancer, and cardiovascular diseases (Domingueti et al., 2016).

Ingredients of Weight-Less per capsule

  • 7-Keto DHEA- 25mg (helps to burn fat)
  • 2 Brown Seaweed extracts- 200mg (help to lower and prevent high blood sugar levels, offers a strong anti-inflammatory, and supports weight loss)

Take 1 – 2 capsules of Weight-less one-half hour before meals, especially important before your carbohydrate (or meat) laden meals.* (See Green Facts on meat and diabetes)

Food Science

The ingredients in Weight-less have been shown to reduce both the states of hyperglycemia and oxidative stress. The Kelp and Bladderwrack polyphenol extracts (phlorotannins) offer organic-certified bioactive ingredients that (1) act on amylase and glucosidase enzymes to optimize post-meal blood glucose and insulin responses and (2) demonstrate that they have a high total antioxidant activity as verified by the Total ORAC 6.0 assay.

The phenols in the kelp and bladderwrack have superior antioxidant activity – a neutralizing effect – on the primary free radical superoxide anion. Superoxide  anion is known as the “mother of  free radicals” because  it also can become a hydroxyl ROS, a nitrogen RNS and a hydrogen peroxide ROS.

Thus, Weight-Less helps prevent post-meal hyperglycemia and has a direct scavenging action on excess free radical generation.  The key is not to totally neutralize all free radical activity but to bring about a healthy redox homeostasis.

References:

  • Domingueti, C. P., Dusse, L. M. S. A., das Graças Carvalho, M., de Sousa, L. P., Gomes, K. B., & Fernandes, A. P. (2016). Diabetes mellitus: The linkage between oxidative stress, inflammation, hypercoagulability and vascular complications. Journal of diabetes and its complications, 30(4), 738-745.
  • Hulsmans, M., & Holvoet, P. (2010). The vicious circle between oxidative stress and inflammation in atherosclerosis. Journal of cellular and molecular medicine, 14(1‐2), 70-78.
  • InterAct Consortium. (2013). Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study. Diabetologia, 56(1), 47-59
  • Gutowski, M., & Kowalczyk, S. (2013). A study of free radical chemistry: their role and pathophysiological significance. Acta Biochimica Polonica, 60(1), 1-16.
  • Valko, M., Rhodes, C., Moncol, J., Izakovic, M. M., & Mazur, M. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-biological interactions, 160(1), 1-40.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3High meat intake is also shown in research to generate oxidatative stress and hyperglacemia. We will discuss this in another email but meanwhile, see Dr. Greger’s informative video on Why is meat a risk factor for diabetes?
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

The New High ORAC Synbiotic

September 18, 2017

Dear Friends
HO Front Low Rez
We are very excited to present to you our High ORAC Synbiotic.  It’s back with an enhanced formula and a new look—a beautiful new label.

What’s new?

A higher probiotics count:  We’ve increased the CFUs (Colony Forming Units) to 25 billion per capsule.

More berries and extracts: We have added Quercetin, Resveratrol, and Strawberry.

Higher ORAC value:  The berry mixture provides 3000 ORAC (Oxygen Radical Absorbent Capacity)!

Let’s look at the new proprietary blend per capsule:

  • L. acidophilus & B. longum– 250mg
  • Grape Seed Extract, Wild Blueberry, Quercetin, Resveratrol, Wild Bliberry, Cranberry, Tart Cherry, Prune, Raspberry Seed, Strawberry & Inulin- 250mg.

Please notice that underneather the High ORAC Synbiotic name on the label it say:  “Post Antibiotic Care”.  (See Food Science and the References below for the scientific  conversation on this topic.)

Food Science:

The problem with antibiotics is that along with killing off the bad bacteria, antibiotics also kill the good gut bacteria — the protective bacteria such as Lactobaccilus and Bifidobacteria.  For many years researchers have warned us that antibiotics destroy the protective layer of good bacteria on our gut membrane, resulting in chronic inflammation (Barbut,f. & Petit, J.C., 2001; Bergogne-Berezin, E., 2000).

Both the Bifidobacteria longum and the Lactobacillus acidophilus strains are used in the High ORAC Synbiotic Formula to re-colonize and protect the GI membrane after antibiotic therapy. Bifidobacteria longum and Lactobacillus acidophilus colonize the GI tract membrane, thereby blocking out the pathogens; and also kill pathogenic microorganisms by producing antimicrobial peptides (bacterocins) against them (Hickson et al., 2007; Syngai et al., 2016).

The large offering of berry polyphenols, organic acids, and other phytochemicals offer a powerful antimicrobial and anti-inflammatory support (Grace et al., 2014; Nohynek et al., 2006) . Along with the inulin (a soluble fiber derived from organic chicory root), berries are also a great prebiotic for these good lactic acid bacteria (Puupponen-Pimia et al., 2005; Vendrame et al., 2011). (See the links to the references below for scientific support.)

References:

  • Barbut, F., & Petit, J. C. (2001). Epidemiology of Clostridium difficile‐associated infections. Clinical Microbiology and Infection, 7(8), 405-410.
  • Bergogne-Berezin, E. (2000). Treatment and prevention of antibiotic associated diarrhea. International journal of antimicrobial agents, 16(4), 521-526.
  • Cardona, F., Andrés-Lacueva, C., Tulipani, S., Tinahones, F. J., & Queipo-Ortuño, M. I. (2013). Benefits of polyphenols on gut microbiota and implications in human health. The Journal of nutritional biochemistry, 24(8), 1415-1422. http://www.sciencedirect.com/science/article/pii/S0955286313000946
  • Cremonini FI, Di Caro SI, Nista EC, Bartolozzi F, Capelli GI, Gasbarrini G, Gasbarrini AN. (2002). Meta‐analysis: the effect of probiotic administration on antibiotic‐associated diarrhoea. Alimentary pharmacology & therapeutics, 16(8), 1461-1467.
  • Figueroa‐González, I., Quijano, G., Ramírez, G., & Cruz‐Guerrero, A. (2011). Probiotics and prebiotics—perspectives and challenges. Journal of the Science of Food and Agriculture, 91(8), 1341-1348.
  • Grace, M.H., Esposito D., Dunlap K.L., & Lila M.A. (2014). Comparative analysis of phenolic content and profile, antioxidant capacity, and anti-inflammatory bioactivity in wild Alaskan and commercial Vaccinium berries. J Agric Food Chem, 62(18), 4007-17. doi: 10.1021/jf403810y.
  • Hardy, H., Harris, J., Lyon, E., Beal, J., & Foey, A. D. (2013). Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology. Nutrients, 5(6), 1869-1912.
  • Haslam, E., Lilley, T. H., Warminski, E., Liao, H., Cai, Y., Martin, R., … & Luck, G. (1992). Polyphenol complexation: a study in molecular recognition. ACS Publications.
  • Hattori, M., Kusumoto, I. T., Namba, T., Ishigami, T., & Hara, Y. (1990). Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans. Chemical and Pharmaceutical Bulletin, 38(3), 717-720.
  • Joseph, S.V., Edirisinghe, I., & Burton-Freeman, B.M. (2014). Berries: anti-inflammatory effects in humans. J Agric Food Chem, 7; 62(18), 3886-903. DOI:10.1021/jf4044056
  • Kemperman, R.A., Bolca, S., Roger, L.C., Vaughan, E.E. (2010). Novel approaches for analysing gut microbes and dietary polyphenols: challenges and opportunities
    Microbiology, 156 (11), pp. 3224-3231
  • Ng, S. C., Hart, A. L., Kamm, M. A., Stagg, A. J., & Knight, S. C. (2009). Mechanisms of action of probiotics: recent advances. Inflammatory bowel diseases, 15(2), 300-310.
  • Nohynek, L. J., Alakomi, H. L., Kähkönen, M. P., Heinonen, M., Helander, I. M., Oksman-Caldentey, K. M., & Puupponen-Pimiä, R. H. (2006). Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens. Nutrition and cancer, 54(1), 18-32.
  • Puupponen-Pimiä, R., Nohynek, L., Hartman-Schmidlin, S., Kähkönen, M. Heinonen, M., Mata-Riihinen, K. et al.(2005). Berry phenolics selectively inhibit the growth of intestinal pathogens.  J. Appl Microbiol, 98, pp. 991-1000
  • Sirk, T. W., Friedman, M., & Brown, E. F. (2011). Molecular binding of black tea theaflavins to biological membranes: relationship to bioactivities. Journal of agricultural and food chemistry, 59(8), 3780-3787.
  • Sirk, T. W., Brown, E. F., Friedman, M., & Sum, A. K. (2009). Molecular binding of catechins to biomembranes: relationship to biological activity. Journal of agricultural and food chemistry, 57(15), 6720-6728.
  • Stapleton, P. D., Shah, S., Ehlert, K., Hara, Y., & Taylor, P. W. (2007). The β-lactam-resistance modifier (−)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Microbiology, 153(7), 2093-2103.
  • Syngai, G. G., Gopi, R., Bharali, R., Dey, S., Lakshmanan, G. A., & Ahmed, G. (2016). Probiotics-the versatile functional food ingredients. Journal of Food Science and Technology, 53(2), 921-933. doi:  10.1007/s13197-015-2011-0
  • Vendrame, S., & Klimis-Zacas, D. (2015). Anti-inflammatory effect of anthocyanins via modulation of nuclear factor-κB and mitogen-activated protein kinase signaling cascades. Nutr Rev, 73(6), 348-58. DOI:10.1093/nutrit/nuu066.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Bacteria in an average human body number ten times more than human cells, for a total of about 1000 more genes than are present in the human genome.  An ever-growing number of studies have demonstrated that changes in the composition of our microbiomes correlate with numerous disease states, raising the possibility that manipulation of these communities could be used to treat disease.   Check out NIH’s the Human Microbiome Projects 2017 website.
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends
Phyto Power High Rez
Stull’s (2016) review, Blueberries’ Impact on Insulin Resistance and Glucose Intolerance, highlighted a multitude of in vivo and in vitro studies that demonstrated another of blueberries important attributes — the anti-diabetic effects of blueberries and berry extracts in insulin-resistant rodent, human, and cell culture models.

The scientific evidence in support of the anti-diabetic health benefits of blueberries and blueberry extract is encouraging. Epidemiological studies reported that consumption of foods rich in anthocyanins, especially from blueberries, were associated with a lower risk of type 2 diabetes (T2DM) and of peripheral insulin resistance.

Prediabetes is a condition in which blood glucose levels are higher than normal, but not high enough to be classified as T2DM.  Although the prediabetes stage is when corrective actions need to be implemented to prevent the possible development of T2DM, many studies find blueberries to have an anti-diabetic effect. See the references below.

Dinstel et al. (2013) found the blueberries in Alaska to have the highest anthocyanins content. See Green Facts below. Our Phyto Power utilizes Alaskan blueberries’ potent levels of plant phenols.

Phyto Power is comprised of several species of wildcrafted blueberries, Rose hip, and Dandelion, including their leaves, stems, roots, and flowers. Growing wild and strong in remote areas of Alaska, these berries and plants are handpicked at the peak of their phytonutrient potential. For centuries, indigenous tribes of Alaskan Natives have used these power-filled berries and plants for their daily nourishment as well as ceremonial and medicinal purposes

Learn how to use Phyto Power in our research and description tabs.

References:

  • Dinstel R.R., Cascio J., & Koukel S. (2013). The antioxidant level of Alaska’s wild berries: high, higher and highest. Int J Circumpolar Health, 72. DOI: 10.3402/ijch.v72i0.21188
  • Haffner, S.M. (1996). The insulin resistance syndrome revisited. Diabetes Care,19:275-277. doi: 10.2337/diacare.19.3.275.
  • Jennings, A., Welch, A. A., Spector, T., Macgregor, A., & Cassidy, A. (2014). Intakes of anthocyanins and flavones are associated with biomarkers of insulin resistance and inflammation in women. The Journal of nutrition, 144(2), 202-208.
  • Muraki, I., Imamura, F., Manson, J. E., Hu, F. B., Willett, W. C., van Dam, R. M., & Sun, Q. (2013). Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies. Bmj, 347, f5001.
  • Stull, A. J. (2016). Blueberries’ Impact on Insulin Resistance and Glucose Intolerance. Antioxidants, 5(4), 44. doi:  10.3390/antiox5040044
  • Wedick N.M., Pan A., Cassidy A., Rimm E.B., Sampson L., Rosner B., Willett W., Hu F.B., Sun Q., van Dam R.M. (2012). Dietary flavonoid intakes and risk of type 2 diabetes in US men and women.  Am. J. Clin. Nutr, 95:925–933. doi: 10.3945/ajcn.111.028894.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3Dinstel et al. (2013) found the antioxidant levels of Alaska’s wild berries to be extremely high, ranging from 3 to 5 times higher in ORAC values than cultivated berries from 48 other states. For example, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. When the berries were dehydrated, per gram the ORAC values increased.*
 

©2005 – 2017 BioImmersion Inc. All Rights Reserved

Dear Friends

Boron is one of the most important minerals in our diet.  How are your boron levels?

The average American’s boron levels are 1 mg/day; and, many studies have shown that the benefits to be derived from boron intake don’t occur until levels of 3 mg/day and above are achieved (Price et al., 2012).
FB Photo 2 8

BioImmersion’s Fructo Borate Complex is a new form of boron supplementation that duplicates the exact nature of the molecular structure of dietary boron found in fruits and vegetables— that is, boron in the food chain is always found bound to carbohydrate (US Patent #5,902,049).

Fructo Borate Complex contains 240 mg of Fructo Borate along with 260 mg of calcium ascorbate to provides 6 mg of elemental boron.  There is 500 mg per vegetarian capsule with 60 capsules per bottle.  There are no excipients of any kind.

Boron is found to be a missing mineral in our daily nutrition as industrialized farming has depleted boron from our soil. Fructo Borate Complex is a complex of calcium, natural fructose, and boron; exactly as it is found in fresh and dried fruits, vegetables, herbs and wine (Miljkovic et al., 2009; Price et al., 2012).  This form of boron is not only safe but also bioavailable compared with most commercial forms of boron (Scorei et al., 2011).

(See the references to the above concluding bullet points in the 2015 paper by Lara Pizzorno entitled, Nothing Boring About Boron)

What are possible benefits from adequate boron intake?

  • Is essential for the growth and maintenance of bone.
  • Greatly improves wound healing.
  • Beneficially impacts the body’s use of estrogen, testosterone, and vitamin D.
  • Boosts magnesium absorption.
  • Reduces levels of inflammatory biomakers, such as hs-CRP and TNF-alpha.
  • Raises levels of antioxidant enzymes, such as SOD, catalase and glutathione peroxidase.
  • Protects against pesticide-induced oxidative stress and heavy-metal toxicity.
  • Improves brain electical activity, cognitive performance, and short-term memory in elders.
  • Influences the formation and activity of key biomolecules, such as SAM-e and NAD.
  • Has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers and multiple and non-Hodgkin’s lymphoma.
  • May help ameliorate the adverse effects of traditional chemotherapeutic agents.

References:

  • Miljkovic et al. (2009). Calcium Fructoborate:  plant-based dietary boron for human nutrition. J Diet Suppl;6:211-226.
  • Pizzorno, L. (2015). Nothing Boring About Boron. Integr Med (Encinitas); 14(4): 35-48.
  • Price et al. (2012). Essential Nutrients of Bone Health and a Review of their Availability in the Average North American Diet. Orthop J;6:143-149.
  • Scorei et al. (2011). A Double-blind, Placebo-Controlled Pilot Study to Evaluate the Effect of Calcium Fructoborate on Systemic Inflammation and Dyslipidemia Markers for Middle-Ased People with Primary Osteoarthritis. Biol Trace Elem Res;144:253-263.
  • Scorei et al. (2011). Calcium Fructoborate—potential anti-inflammatory agent. Biol Trace Elem. Res; doi:10.1007/s12011-011-8972-6.

Sincerely yours,

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

Globe_Home 3We’ve been talking, in our last two emails, about the deficiency of certain minerals in our diet, largely in part because they have become missing in our soil due to faulty farming methods.  If they aren’t in the soil, they won’t be in plants coming from these farms.

The following link is a fabulous and totally inspiring TED talk given by farmer Gabe Brown presenting us with an absolute solution on how we can feed the world if we start farming with nature as he has impressively demonstrated in North Dakota on his massive farm.  The Febuary 2016 talk is called: Regeneration of our Lands: A Producer’s Perspective.

 

©2005 – 2017 BioImmersion Inc. All Rights Reserved